Abstract: The present disclosure provides a method of treating asthma in a subject at risk of asthma exacerbation, and a method of as-needed treatment or prevention of bronchoconstriction in a subject, and/or prevention of exacerbation in a subject with asthma, comprising administering as needed to the subject a composition comprising therapeutically effective amounts of albuterol and budesonide, wherein the composition is administered via a metered dose inhaler, wherein the method reduces risk of severe asthma exacerbation by at least about 15% as compared to administration of a composition comprising a same dose of albuterol alone, as measured by time-to-first severe asthma exacerbation.

Abstract: Improved molecular breeding methods include a method in which an association data set is developed by associating the phenotypes of a broad population of individuals with the individual genotypes. The association data set is used in conjunction with a growth model in order to select breeding pairs likely to generate offspring with one or more desirable traits.

Abstract: Improved molecular breeding methods include a method in which an association data set is developed by associating the phenotypes of a broad population of individuals with the individual genotypes. The association data set is used in conjunction with a growth model in order to select breeding pairs likely to generate offspring with one or more desirable traits.

Abstract: Systems and methods that integrate breeding and agronomy by employing genotype (G) by environment (E) by management (M) practice to improve synchronized breeding for crop yield gain are provided. Methods to perform G×E×M through machine learning, simulation, crop models, quantitative models and other prediction techniques are provided.

Abstract: Methods to improve drought tolerance and increasing yield by the application limited transpiration trait in maize plants are provided. Expression of the limited transpiration trait in maize under increasing vapor pressure deficit conditions provide positive impact on overall crop yield, depending on environmental conditions.

Abstract: A distributed system processing a publisher's streaming data. The distributed system comprises multiple workers and publisher data stores, each publisher data store dedicated to a worker and a publisher. A sampling ratio (the fraction of data items for storage in the publisher's data store) is selected by a publisher data store's worker based on historical information. At least two workers select different sampling ratios. Data items representing an interaction between an entity and the publisher are received. Each data item is assigned to a worker for processing. A hash function is applied to the data item's identifier, resulting in a key value falling within the hash function's range. The scope of the publisher's data store is equal to the hash function's range multiplied by the sampling ratio of the publisher's data store. A data item with a key value within the scope of the publisher's data store is stored therein.

Abstract: Embodiments are directed to generating and managing an advertising campaign based on a third-party sales listing. In particular, an identifier associated with a sales listing posted over a third-party service from a user of the third-party service is received. Sales listing data for the sales listing is retrieved from the third-party service using the identifier associated with the sales listing. Thereafter, an advertising campaign is automatically generated based at least in part on the retrieved sales listing data. In one aspect, generation of the advertising campaign includes generating an advertising creative using the retrieved sales listing data. Subsequently, bidding on an advertising opportunity in an auction is performed according to the generated advertising campaign. Responsive to winning the auction, an advertisement based on the advertising creative is provided to a content provider associated with the advertising opportunity.

Abstract: The original contoured thumb and finger pick for players of stringed instruments introduced an incredible innovation for guitar players and others. Improvements based on this unique concept have transformed a useful tool into an extremely comfortable and natural strumming aid. The pick saddle totally follows the thumb and finger contours for greater comfort and the band is secured to the pick with a low profile post.

Abstract: A distributed system processing a publisher's streaming data. The distributed system comprises multiple workers and publisher data stores, each publisher data store dedicated to a worker and a publisher. A sampling ratio (the fraction of data items for storage in the publisher's data store) is selected by a publisher data store's worker based on historical information. At least two workers select different sampling ratios. Data items representing an interaction between an entity and the publisher are received. Each data item is assigned to a worker for processing. A hash function is applied to the data item's identifier, resulting in a key value falling within the hash function's range. The scope of the publisher's data store is equal to the hash function's range multiplied by the sampling ratio of the publisher's data store. A data item with a key value within the scope of the publisher's data store is stored therein.

Abstract: A novel maize variety designated X03H001 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X03H001 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03H001 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X03H001, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03H001. This invention further relates to methods for producing maize varieties derived from maize variety X03H001.

Abstract: A distributed system processing a publisher's streaming data. The distributed system comprises multiple workers and publisher data stores, each publisher data store dedicated to a worker and a publisher. A sampling ratio (the fraction of data items for storage in the publisher's data store) is selected by a publisher data store's worker based on historical information. At least two workers select different sampling ratios. Data items representing an interaction between an entity and the publisher are received. Each data item is assigned to a worker for processing. A hash function is applied to the data item's identifier, resulting in a key value falling within the hash function's range. The scope of the publisher's data store is equal to the hash function's range multiplied by the sampling ratio of the publisher's data store. A data item with a key value within the scope of the publisher's data store is stored therein.

Abstract: Methods to improve drought tolerance and increasing yield by the application limited transpiration trait in maize plants are provided. Expression of the limited transpiration trait in maize under increasing vapor pressure deficit conditions provide positive impact on overall crop yield, depending on environmental conditions.

Abstract: A novel maize variety designated X00H315 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X00H315 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00H315 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00H315, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00H315. This invention further relates to methods for producing maize varieties derived from maize variety X00H315.

Abstract: Embodiments are directed to generating and managing an advertising campaign based on a third-party listing. In particular, an identifier associated with a listing posted over a third-party service from a user of the third-party service is received. Listing data for the listing is retrieved from the third-party service using the identifier associated with the listing. Thereafter, an advertising campaign is automatically generated based at least in part on the retrieved listing data. In one aspect, generation of the advertising campaign includes generating an advertising creative using the retrieved listing data. Subsequently, an advertising opportunity is selected according to the generated advertising campaign. Following the selection, an advertisement based on the advertising creative is provided to a content provider associated with the advertising opportunity.

Abstract: A novel maize variety designated PH25AG and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH25AG with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH25AG through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH25AG or a locus conversion of PH25AG with another maize variety.

Abstract: A novel maize variety designated X00H315 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X00H315 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00H315 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00H315, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00H315. This invention further relates to methods for producing maize varieties derived from maize variety X00H315.

Abstract: Improved molecular breeding methods include a method in which an association data set is developed by associating the phenotypes of a broad population of individuals with the individual genotypes. The association data set is used in conjunction with a growth model in order to select breeding pairs likely to generate offspring with one or more desirable traits.

Abstract: An improved system for monitoring vibration of an electric machine is disclosed. According to one embodiment, sensors are positioned in a plane orthogonal to the motor shaft and each sensor detects vibration along at least one axis of the motor. The sensors are oriented such that the polarity of each sensor is reversed. The pairs of sensors may be used to isolate specific vibrations within the motor. According to another embodiment, a sensor may be mounted directly to the motor shaft. The sensor on the motor shaft directly detects vibrations along the motor shaft. Optionally, a second sensor may be mounted to a fixed location within the motor housing, and the combination of the sensor on the motor shaft and the sensor at a fixed location may be used to isolate specific vibrations within the motor. A motor controller may adjust operation of the motor to reduce the isolated vibration.

Abstract: An excavation apparatus is disclosed. The excavation apparatus includes a chassis having a length that extends from a front end to a rear end of the chassis. The chassis also has a width oriented perpendicular to the length. A boom is pivotally attached to the rear end of the chassis. A cutting component mounted to the boom. A shroud structure at least partially covers the cutting component. A source of vacuum is in fluid communication with an interior of the shroud structure for drawing air containing dust from the interior of the shroud structure. A filter filters the air drawn from the interior of the shroud structure by the source of vacuum. A dust barrier projects downwardly from the shroud structure and extends along at least a portion of a perimeter of the shroud structure.

Abstract: Disclosed herein are methods and compositions for the treatment of diseases of the CNS with nucleic acid nanoparticles. Compositions are also disclosed herein that utilize nucleic acid nanoparticles to treat conditions such as Parkinson's Disease. Furthermore, methods of intranasally administering the compacted nucleic acid nanoparticles for therapeutic purposes in the brain are disclosed.