Abstract: The present invention relates to derivatives of known active pharmaceutical compounds. These derivatives are differentiated from the parent active compound by virtue of being redox derivatives of the active compound. This means that one or more of the functional groups in the active compound has been converted to another group in one or more reactions which may be considered to represent a change of oxidation state. We refer to these compounds generally as redox derivatives. The derivatives of the invention may be related to the original parent active pharmaceutical compound by only a single step transformation, or may be related via several synthetic steps including one or more changes of oxidation state.

Abstract: A concealable handgun holster is disclosed with a handgun encasement supported within clothing of a wearer by one or more attachment clips, the attachment clips being hidden “in plain sight” by decorative features that deceive an observer into thinking the clips are decorations rather than part of a holster. In preferred embodiments, the holster is a hybrid holster with a handgun encasement formed by a leather sheet attached to a rigid plastic cover, preferably made of Kydex®. The clips can be plastic or metal, preferably steel, and can be attached to the encasement by rivets, screws, or any other suitable fastening means known in the art. Decoration of the attachment clips can be by shaping of the clips, perforation of the clips with decorative shapes, engraving on the clips, printing on the clips, and/or attachment of decorative items to the clips.

Abstract: The present invention relates to derivatives of known active pharmaceutical compounds. These derivatives are differentiated from the parent active compound by virtue of being redox derivatives of the active compound. This means that one or more of the functional groups in the active compound has been converted to another group in one or more reactions which may be considered to represent a change of oxidation state. We refer to these compounds generally as redox derivatives. The derivatives of the invention may be related to the original parent active pharmaceutical compound by only a single step transformation, or may be related via several synthetic steps including one or more changes of oxidation state. In certain cases, the functional group obtained after two or more transformations may be in the same oxidation state as the parent active compound (and we include these compounds in our definition of redox derivatives).

Abstract: A concealable handgun holster is disclosed with a handgun encasement supported within clothing of a wearer by one or more attachment clips, the attachment clips being hidden “in plain sight” by decorative features that deceive an observer into thinking the clips are decorations rather than part of a holster. In preferred embodiments, the holster is a hybrid holster with a handgun encasement formed by a leather sheet attached to a rigid plastic cover, preferably made of Kydex®. The clips can be plastic or metal, preferably steel, and can be attached to the encasement by rivets, screws, or any other suitable fastening means known in the art. Decoration of the attachment clips can be by shaping of the clips, perforation of the clips with decorative shapes, engraving on the clips, printing on the clips, and/or attachment of decorative items to the clips.

Abstract: A concealable hybrid holster is disclosed that includes metal attachment clips for enhanced strength and flexibility, thereby providing increased attachment durability during long term use. The holster includes a leather sheet to which is attached a rigid plastic encasement, preferably made of Kydex®, thereby forming a compartment suitable for carrying a concealed handgun. The metal clips are preferably made of steel, more preferably of spring steel, and can be attached to the leather sheet of the hybrid holster by rivets, screws, or any other suitable fastening means. Due to the inherent strength of steel, the steel attachment clips are thinner and/or smaller than prior art attachment clips made from plastic, and so provide better concealment of the holster as compared to the prior art.