Patents by Inventor Mark D. Does

Mark D. Does has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12189004
    Abstract: Accurate measurement of gradient waveform errors can often improve image quality in sequences with time varying readout and excitation waveforms. Self-encoding or offset-slice method sequences are commonly used to measure gradient waveforms. However, the self-encoding method requires a long scan time, while the offset-slice method is often low precision, requiring the thickness of the excited slice to be small compared to the maximal k-space encoded by the test waveform. This disclosure describes a novel hybrid of those methods, referred to as variable-prephasing (VP). Like the offset-slice method, VP uses the change in signal phase from offset-slices to calculate the gradient waveform. Similar to the self-encoding method, repeated acquisitions with a variable amplitude self-encoding gradient mitigates the signal loss due to phase wrapping, which, in-turn, allows thicker slices and greater SNR.
    Type: Grant
    Filed: February 3, 2023
    Date of Patent: January 7, 2025
    Assignee: Vanderbilt University
    Inventors: Kevin Harkins, Mark D. Does
  • Patent number: 12082916
    Abstract: An implantable bioresorbable radio frequency (RF) coil for high-resolution and high-specificity post-surgical evaluating or monitoring with magnetic resonance imaging (MRI) is disclosed. The coil includes a bioresorbable conductor configured to be resorbed within a patient while the coil is implanted in the patient. In one embodiment, the target application of this coil is the evaluation or monitoring (via MRI) of peripheral nerve regeneration following surgical repair.
    Type: Grant
    Filed: March 1, 2021
    Date of Patent: September 10, 2024
    Assignees: Vanderbilt University, Northwestern University
    Inventors: Mark D. Does, John A. Rogers
  • Publication number: 20230251340
    Abstract: Accurate measurement of gradient waveform errors can often improve image quality in sequences with time varying readout and excitation waveforms. Self-encoding or offset-slice method sequences are commonly used to measure gradient waveforms. However, the self-encoding method requires a long scan time, while the offset-slice method is often low precision, requiring the thickness of the excited slice to be small compared to the maximal k-space encoded by the test waveform. This disclosure describes a novel hybrid of those methods, referred to as variable-prephasing (VP). Like the offset-slice method, VP uses the change in signal phase from offset-slices to calculate the gradient waveform. Similar to the self-encoding method, repeated acquisitions with a variable amplitude self-encoding gradient mitigates the signal loss due to phase wrapping, which, in-turn, allows thicker slices and greater SNR.
    Type: Application
    Filed: February 3, 2023
    Publication date: August 10, 2023
    Inventors: Kevin Harkins, Mark D. Does
  • Publication number: 20230103510
    Abstract: An implantable bioresorbable radio frequency (RF) coil for high-resolution and high-specificity post-surgical evaluating or monitoring with magnetic resonance imaging (MRI) is disclosed. The coil includes a bioresorbable conductor configured to be resorbed within a patient while the coil is implanted in the patient. In one embodiment, the target application of this coil is the evaluation or monitoring (via MRI) of peripheral nerve regeneration following surgical repair.
    Type: Application
    Filed: March 1, 2021
    Publication date: April 6, 2023
    Inventors: Mark D. Does, John A. Rogers