Patents by Inventor Mark D. Kafka

Mark D. Kafka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors
    Patent number: 7897615
    Abstract: The present invention provides previous methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.
    Type: Grant
    Filed: October 2, 2007
    Date of Patent: March 1, 2011
    Assignee: Chugai Sciyaku Kabushiki Kaisha
    Inventors: Mark D. Kafka, Mark E. Wilson, Anna Russell, Gary D. Lopaschuk, Jason R. Dyck
  • Cyanoamide Compounds Useful as Malonyl-COA Decarboxylase Inhibitors
    Publication number: 20080161358
    Abstract: The present invention provides previous methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.
    Type: Application
    Filed: October 2, 2007
    Publication date: July 3, 2008
    Inventors: Mark D. Kafka, Mark E. Wilson, Anna Russell, Gary D. Lopaschuk, Jason R. Dyck
  • Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors
    Patent number: 7285562
    Abstract: The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway.
    Type: Grant
    Filed: July 28, 2004
    Date of Patent: October 23, 2007
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Mark D. Kafka, Mark E. Wilson, Anna Russell, Gary D. Lopaschuk, Jason R. Dyck