Abstract: A process and/or a bioreactor control system for controlling a bioreactor. The bioreactor control system includes a bioreactor, a sensor, an electronic card, and a bioreactor controller. The sensor is proximate to the bioreactor and configured to generate a signal indicative of an operating condition of the bioreactor. The signal is then transmitted to the electronic card. Receiving the signal, the electronic card processes the signal to generate a converted signal. The converted signal is then transmitted to the bioreactor controller. The bioreactor controller, in turn, processes the converted signal and generates a control signal to modify the operating condition of the bioreactor.

Abstract: A process and/or a bioreactor control system for controlling a bioreactor. The bioreactor control system includes a bioreactor, a sensor, an electronic card, and a bioreactor controller. The sensor is proximate to the bioreactor and configured to generate a signal indicative of an operating condition of the bioreactor. The signal is then transmitted to the electronic card. Receiving the signal, the electronic card processes the signal to generate a converted signal. The converted signal is then transmitted to the bioreactor controller. The bioreactor controller, in turn, processes the converted signal and generates a control signal to modify the operating condition of the bioreactor.

Abstract: A method for enhancing mixing and aeration of a liquid reaction medium in a toroidal bioreactor vessel includes dispensing a liquid reaction medium into an interior of a toroidal bioreactor vessel, the interior being bounded by an inner surface, a textured surface being arranged on at least a portion of the inner surface, the textured surface having a plurality of upstanding protuberances. The toroidal bioreactor vessel is rotated in an orbital motion such that there is a resonant frequency traveling wave of the fluid orbiting in one direction in the interior of the toroidal bioreactor vessel when a particular orbital speed is imparted to the toroidal bioreactor vessel.

Abstract: A cylindrical or annular polymeric bioreactor is disclosed which provides enhanced mixing and aeration of the growth medium while simultaneously offering reduced mechanical shear force.

Abstract: The present set of embodiments relate to an environmental condition monitoring and control system employing a software based virtual transmitter for a bioreactor or mixer. The system includes a probe for measuring a condition in a bioreactor that can generate a signal. Measured conditions may include pH, DO, temperature, and pressure. The signal can travel to an electronic card capable of converting the signal from analog to digital and the card can then send the converted signal to a digital controller. The condition monitoring and control system eliminates hardware redundancies and increases versatility by then displaying the converted signal in a software-based virtual transmitter on a non-dedicated human machine interface.

Abstract: A bioreactor monitoring and/or control system utilizing only non-dedicated user input and information display devices, a digital controller and software, said system comprising: i) at least one diagnostic probe for measuring operating conditions in a bioreactor; ii) signal conditioning and communication electronics which supply operating current and/or voltage to said probe and which convert the diagnostic signal into a format accessible by iii) a digital controller which directly receives the format converted signal and transmits it to iv) software which enables the display device to show the converted signal, and also to instruct the controller to implement changes in the operating conditions in the reactor, and v) a software-based virtual transmitter which substantially replicates the keyboard, display, menu-tree and response of a physical sensor transmitter.

Abstract: A cylindrical or annular polymeric bioreactor is disclosed which provides enhanced mixing and aeration of the growth medium while simultaneously offering reduced mechanical shear force.

Abstract: A data management system for a biological process, comprising: a. a single-use component, b. a tag assembly, including a non-volatile memory storage component, that is associated with the single-use component, c. the memory storage component including a unique identification and a memory, and at least one data element that describes a key performance, calibration or control parameter of the single-use component d. a memory reader useable to obtain the identification from the memory storage component.

Abstract: A data management system for a biological process, comprising: a. a single-use component, b. a tag assembly, including a non-volatile memory storage component, that is associated with the single-use component, c. the memory storage component including a unique identification and a memory, and at least one data element that describes a key performance, calibration or control parameter of the single-use component d.

Abstract: A laser tissue treatment device capable of being handheld, the device comprising a semiconductor diode or diode array laser which emits energy and a device for surface cooling of tissue such that the energy is directed through said cooling device in contact with tissue. The diode laser operates at wavelengths between about 630 nm and 980 nm, and delivers a predetermined amount of energy in a predetermined period of time and having a predetermined spot size. The device utilizes one or more microlenses or microlens arrays to collimate the diode laser energy. Optionally, the device utilizes a deflecting optic for deflecting the diode laser energy through the cooling device which is in contact with tissue in which the deflecting optic is visually transparent such that the operator can see the tissue treatment area. A cooling device such as a sapphire plate or other active or passive cooling means is used to cool the tissue.

Abstract: An efficient, fundamental transverse mode selected, diode pumped, solid state laser is disclosed. The laser consists of a slab of laser gain material such as Nd:YLF. Cavity forming optics are positioned around the slab of laser gain material. A laser diode bar, collimated by a micro-lens is used for side pumping a constrained gain region in the slab of laser gain material, with the dimensions transverse to the direction of beam propagation of the constrained gain region being smaller in at least one axis than the transverse dimensions of the fundamental transverse mode volume in the laser gain material. The cavity forming optics and the side pumping of the constrained gain region act in conjunction such that the fundamental transverse mode is automatically selected in the solid state laser.