Patents by Inventor Mark D. Titus

Mark D. Titus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8404253
    Abstract: The present invention is a culture of cells of Haemophilus parasuis exhibiting attenuated pathogenicity and capable of triggering a protective immune response when administered to pigs as a live vaccine. The present invention is also a method of preparing the cell culture, a method of preparing a vaccine from the cell culture, and a live vaccine based on the cell culture. The cell culture was modified from a pathogenic parent strain by MNNG mutagenesis and was selected by complete dependence on streptomycin for growth.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: March 26, 2013
    Inventors: Simone R. Oliveira, Randy R. Simonson, Jonathan D. Mahlberg, Mark D. Titus, Tracy A. Oleson
  • Publication number: 20100255035
    Abstract: The present invention is a culture of cells of Haemophilus parasuis exhibiting attenuated pathogenicity and capable of triggering a protective immune response when administered to pigs as a live vaccine. The present invention is also a method of preparing the cell culture, a method of preparing a vaccine from the cell culture, and a live vaccine based on the cell culture. The cell culture was modified from a pathogenic parent strain by MNNG mutagenesis and was selected by complete dependence on streptomycin for growth.
    Type: Application
    Filed: December 28, 2006
    Publication date: October 7, 2010
    Applicant: Newport Laboratories, Inc.
    Inventors: Simone R. Oliveira, Randy R. Simonson, Jonathan D. Mahlberg, Mark D. Titus, Tracy A. Oleson