Patents by Inventor Mark D. Williams
Mark D. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8544686Abstract: A system for dispensing sprayable material such as paint and other liquefied products. The system includes a dispenser designed to accept a flexible, crushable, container filled with sprayable material and having a valve and spray tip at one end. The container is placed into a slot in the dispenser with the valve on the container secured in the housing of the dispenser. In operation, a plunger that runs lengthwise within the housing of the dispenser exerts force on the bottom of the container crushing it as it is emptied and forcing the sprayable material out through the valve and spray tip.Type: GrantFiled: July 7, 2010Date of Patent: October 1, 2013Assignee: Aervoe Industries, Inc.Inventor: Mark D. Williams
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Publication number: 20110171200Abstract: Provided herein are methods, oligonucleotides and peptide nucleic acids, compositions and kits for predicting a subject's response to treatment with activated protein C or protein C-like compound or susceptibility to major organ dysfunction or susceptibility to an inflammatory condition. The method generally comprises determining a genotype of said subject at one or more of polymorphic sites in the subject's protein C gene selected from one or more of the following: rs20069915 and one or more polymorphism sites in linkage disequilibrium thereto, selected from one or more of the following: rs2069910; rs2069916; rs2069924; rs2069931; rs1799808; rs2069920; and rs6714364 and may further involve comparing the determined genotype with known genotypes for the polymorphism that correspond with an improved response to treatment with activated protein C or protein C-like compound or correspond to susceptibility to major organ dysfunction or susceptibility to an inflammatory condition.Type: ApplicationFiled: January 15, 2009Publication date: July 14, 2011Inventors: Keith R. Walley, James A. Russell, Asim Sarosh Siddiqui, Anthony Gordon, Mark D. Williams, William L. Macias, Sandra Close Kirkwood
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Publication number: 20110091984Abstract: The present invention is directed to methods of evaluating whether an antigen or vaccine has degraded over time using liquid chromatography. The methods described herein also relate to using liquid chromatography to evaluate the relative potency of a given antigen or vaccine.Type: ApplicationFiled: May 21, 2009Publication date: April 21, 2011Inventors: Mark D. Williams, James Slightom, Frank Roerink
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Publication number: 20100209413Abstract: Methods, oligonucleotides arrays etc. for treating inflammatory conditions and of predicting subject outcome based on polymorphisms in SERPINE1 and/or PROC, alone or in combination, wherein the method of treatment includes administering to the subject an anti-inflammatory agent or an anti-coagulant agent, wherein said subject is determined to have an improved response genotype or combination.Type: ApplicationFiled: February 18, 2008Publication date: August 19, 2010Inventors: Keith R. Walley, James R. Russell, Asim Sarosh Siddiqui, Anthony Gordon, Mark D. Williams, William Louis Macias, Sandra Close Kirkwood
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Patent number: 7135796Abstract: An electrically conductive brush box is located against the upper surface of a base and has crimping tabs located against an oppositely disposed crimping surface. The base is formed of high temperature resistant plastic. A field case housing has a seat with a retention member adapted to retain the base against the seat. A screw is threaded into the field case housing such that the head presses against a surface of the base member to retain the base member in the seat. The screw member is located in non-contacting relationship with the electrically conductive brush box. A spacer member is adapted to space the portion of the crimping tab against the crimping surface away from the field case housing. The brush box includes a biasing member holder and the crimping tabs are located adjacent the holder.Type: GrantFiled: April 29, 2005Date of Patent: November 14, 2006Assignee: Black & Decker Inc.Inventors: Earl M Ortt, Robert J Marcinkowski, Michael J Agnes, Mark D Williams
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Patent number: 7010628Abstract: A device for converting joystick controller generated analog and digital signals into Universal Serial Bus (USB) format, or for converting imported pulse position modulated (PPM) encoded signals from an external radio control (RC) transmitter into USB format data. The device is used, in an embodiment, for controlling simulated RC model aircraft as displayed, for example on a personal computer screen through the use of computer software. In an embodiment, the device includes a pair of two-axis gimbals, an auxiliary channel control potentiometer, and various control key switches to generate analog and digital joystick type signals as a result of direct manipulation by a user. The device also includes microcontroller circuitry for importing PPM signals, such as PPM signals generated by a commercially available model aircraft RC transmitter, to a USB port signal for interface with a computer.Type: GrantFiled: November 17, 2004Date of Patent: March 7, 2006Assignee: Hobbico, Inc.Inventors: Neal E. Cloud, Mark D. Williams, Scott Kemp
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Patent number: 6842804Abstract: A device for converting joystick controller generated analog and digital signals into Universal Serial Bus (USB) format, or for converting imported pulse position modulated (PPM) encoded signals from an external radio control (RC) transmitter into USB format data. The device is used, in an embodiment, for controlling simulated RC model aircraft as displayed, for example on a personal computer screen through the use of computer software. In an embodiment, the device includes a pair of two-axis gimbals, an auxiliary channel control potentiometer, and various control key switches to generate analog and digital joystick type signals as a result of direct manipulation by a user. The device also includes microcontroller circuitry for importing PPM signals, such as PPM signals generated by a commercially available model aircraft RC transmitter, to a USB port signal for interface with a computer.Type: GrantFiled: January 30, 2003Date of Patent: January 11, 2005Assignee: Hobbico, Inc.Inventors: Neal E. Cloud, Mark D. Williams, Scott Kemp
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Patent number: 6798109Abstract: An electrically conductive brush box is located against the upper surface of a base and has crimping tabs located against an oppositely disposed crimping surface. The base is formed of high temperature resistant plastic. A field case housing has a seat with a retention member adapted to retain the base against the seat. A screw is threaded into the field case housing such that the head presses against a surface of the base member to retain the base member in the seat. The screw member is located in non-contacting relationship with the electrically conductive brush box. A spacer member is adapted to space the portion of the crimping tab against the crimping surface away from the field case housing. The brush box includes a biasing member holder and the crimping tabs are located adjacent the holder.Type: GrantFiled: October 31, 2002Date of Patent: September 28, 2004Assignee: Black & Decker Inc.Inventors: Earl M. Ortt, Robert J. Marcinkowski, Michael J. Agnes, Mark D. Williams
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Publication number: 20040084990Abstract: An electrically conductive brush box is located against the upper surface of a base and has crimping tabs located against an oppositely disposed crimping surface. The base is formed of high temperature resistant plastic. A field case housing has a seat with a retention member adapted to retain the base against the seat. A screw is threaded into the field case housing such that the head presses against a surface of the base member to retain the base member in the seat. The screw member is located in non-contacting relationship with the electrically conductive brush box. A spacer member is adapted to space the portion of the crimping tab against the crimping surface away from the field case housing. The brush box includes a biasing member holder and the crimping tabs are located adjacent the holder.Type: ApplicationFiled: October 31, 2002Publication date: May 6, 2004Inventors: Earl M. Ortt, Robert J. Marcinkowski, Michael J. Agnes, Mark D. Williams
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Publication number: 20030229729Abstract: A device for converting joystick controller generated analog and digital signals into Universal Serial Bus (USB) format, or for converting imported pulse position modulated (PPM) encoded signals from an external radio control (RC) transmitter into USB format data. The device is used, in an embodiment, for controlling simulated RC model aircraft as displayed, for example on a personal computer screen through the use of computer software. In an embodiment, the device includes a pair of two-axis gimbals, an auxiliary channel control potentiometer, and various control key switches to generate analog and digital joystick type signals as a result of direct manipulation by a user. The device also includes microcontroller circuitry for importing PPM signals, such as PPM signals generated by a commercially available model aircraft RC transmitter, to a USB port signal for interface with a computer.Type: ApplicationFiled: January 30, 2003Publication date: December 11, 2003Applicant: Hobbico, Inc.Inventors: Neal E. Cloud, Mark D. Williams, Scott Kemp
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Patent number: 6600029Abstract: A novel pathway for the synthesis of polyhydroxyalkanoate is provided. A method of synthesizing a recombinant polyhydroxyalkanoate monomer synthase is also provided. These recombinant polyhydroxyalknoate synthases are derived from multifunctional fatty acid synthases or polyketide synthases and generate hydroxyacyl acids capable of polymerization by a polyhydroxyalknoate synthase.Type: GrantFiled: June 19, 1998Date of Patent: July 29, 2003Assignee: Regents of the University of MinnesotaInventors: David H. Sherman, Mark D. Williams, Yongquan Xue
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Patent number: 6517251Abstract: An overmolded motor bearing is provided for use with an electric motor. A conventional ball-bearing has a rubberized sleeve molded directly onto the bearing so that the bearing and insulating rubber sleeve form a unitary subassembly. The bearing sub-assembly is formed by inserting the conventional ball-bearing directly into the mold of an injection molding machine. Importantly, the rubberized material encapsulating the bearing extends around the outer bearing race and along the side faces of the bearing. In a preferred embodiment, separate nylon washers are installed on either side of the bearing when the bearing is inserted into the mold. The rubberized material is then injection molded around the outer bearing race to capture the nylon washers. The preferred embodiment thus prevents the bearing shields on the side faces of the bearing from being subjected to the injection molding pressures within the mold which can deform and thus damage the bearing shields.Type: GrantFiled: November 9, 2000Date of Patent: February 11, 2003Assignee: Black & Decker Inc.Inventor: Mark D. Williams
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Patent number: 6438501Abstract: The present invention is an improved automated flow through electrode liquid monitoring system. The automated system has a sample inlet to a sample pump, a sample outlet from the sample pump to at least one flow through electrode with a waste port. At least one computer controls the sample pump and records data from the at least one flow through electrode for a liquid sample. The improvement relies upon (a) at least one source of a calibration sample connected to (b) an injection valve connected to said sample outlet and connected to said source, said injection valve further connected to said at least one flow through electrode, wherein said injection valve is controlled by said computer to select between said liquid sample or said calibration sample. Advantages include improved accuracy because of more frequent calibrations, no additional labor for calibration, no need to remove the flow through electrode(s), and minimal interruption of sampling.Type: GrantFiled: December 28, 1998Date of Patent: August 20, 2002Assignee: Battele Memorial InstituteInventors: James E. Szecsody, Mark D. Williams, Vince R. Vermeul
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Publication number: 20020000128Abstract: A method for monitoring a structure (10) for the formation of cracks (18) includes first pretreating a surface (14) of the structure by applying a first coating (30) to the structure which bonds uniformly to the surface of the structure and creates a uniform surface coat. A second coating (40) is applied over the first coating and contains microcapsules (44). The microcapsules rupture in response to cracking of the structure to release a dye or pigment which changes the color of the second coating about the crack. Cracked portions which form in the structure may then be identified by observing color changes (48) in the second coating resulting from eruption of the microcapsules.Type: ApplicationFiled: October 15, 1999Publication date: January 3, 2002Inventor: MARK D. WILLIAMS
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Patent number: 6286875Abstract: A system and method for electrically isolating conduit connections in a gas line system for residential, commercial or industrial applications. Gas line conduit of standard configuration is cut to length and upset at one end to create an annular flange of increased diameter, which then is machined to a desired configuration having annular ridges and flat and tapered surfaces. The other end of the conduit is machined in a standard thread configuration. The flanged portion of the conduit is then placed in an injection molding machine and receives a non-conductive elastomeric, molded seal thereover which includes a tubular pilot portion. A coupling nut slipped over the conduit may then join the conduit to conventional gas line valves, meters or the like in a completely electrically insulated connection.Type: GrantFiled: March 29, 2000Date of Patent: September 11, 2001Assignee: Schuler Manufacturing CompanyInventors: Larry R. Snodgrass, Mark D. Williams
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Patent number: 6168932Abstract: A soluble form of DTctGMCSF is produced with high yield in insect cells, preferably using the baculovirus expression vector system (BEVS).Type: GrantFiled: July 13, 1998Date of Patent: January 2, 2001Assignee: Parker Hughes InstituteInventors: Fatih M. Uckun, Mark D. Williams, Alexander Rostovstev
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Patent number: 5594185Abstract: The present invention comprises a self-contained, modular unit and method of using the same for evaluating the mobility, dissipation and degradation of chemicals and their degradates through a soil matrix. The self-contained, modular unit comprises at least a soil matrix vessel for containing the soil matrix and a leachate collection vessel communicating with the soil matrix vessel for collecting and storing the leachate from the soil matrix vessel. The leachate collection vessel is designed and connected to the soil matrix vessel in such a manner that the collected leachate is observable and removable at ground level, thus eliminating the necessity of digging a trench to view or retrieve the leachate as prior art units required. The preferred embodiment of the self-contained modular unit further comprises a runoff collection vessel which communicates with the soil matrix vessel and collects the runoff from the soil matrix vessel.Type: GrantFiled: June 7, 1995Date of Patent: January 14, 1997Assignee: Analytical Bio Chemistry Laboratories, Inc.Inventors: Martin W. Winberry, Ranga R. Velagaleti, Mark D. Williams, Donna Daly, Len R. Swain, Jerome B. Weber
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Patent number: 5399742Abstract: Disclosed is a process for the manufacture of dialkyl cyclohexanedicarboxylates by the low pressure, catalytic hydrogenation of the corresponding dialkyl benzenedicarboxylate wherein the formation/accumulation of carbon monoxide is suppressed to maintain the activity of the precious metal catalyst.Type: GrantFiled: April 11, 1994Date of Patent: March 21, 1995Assignee: Eastman Chemical CompanyInventors: Brent A. Tennant, Mark D. Williams, Bruce L. Gustafson