Patents by Inventor Mark DARIS

Mark DARIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERING CHARGE PAIR MUTATIONS FOR PAIRING OF HETERO-IgG MOLECULES
    Publication number: 20220389119
    Abstract: The present invention relates to heterodimers comprising antibody CH3 domains and mutations useful for the facilitation of the formation of heterodimers. Methods of optimizing purification of the heterodimers at certain pHs in also disclosed.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 8, 2022
    Inventors: Bram ESTES, Fernando GARCES, Zhulun WANG, Mark DARIS
  • Promoter and Regulatory Elements for Improved Expression of Heterologous Genes in Host Cells
    Publication number: 20170253889
    Abstract: Disclosed are a recombinant expression vector and a host cell that contains the vector.
    Type: Application
    Filed: October 14, 2015
    Publication date: September 7, 2017
    Applicant: AMGEN INC.
    Inventors: Mark DARIS, Jennitte LeAnn STEVENS, Chi-Ming Kevin LI, Huanying GE