Patents by Inventor MARK DAYEL

MARK DAYEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220137075
    Abstract: Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 ?L) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.
    Type: Application
    Filed: September 9, 2021
    Publication date: May 5, 2022
    Inventors: Mark Dayel, Samartha Anekal, Paul Patel, Ian Gibbons, Elizabeth A. Holmes
  • Patent number: 11320355
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: May 3, 2022
    Assignee: Labrador Diagnostics LLC
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Patent number: 11119110
    Abstract: Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 ?L) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: September 14, 2021
    Assignee: Labrador Diagnotics LLC
    Inventors: Mark Dayel, Samartha Anekal, Paul Patel, Ian Gibbons, Elizabeth A. Holmes
  • Publication number: 20210140866
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Application
    Filed: September 22, 2020
    Publication date: May 13, 2021
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Patent number: 10788409
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: September 29, 2020
    Assignee: Labrador Diagnostics LLC
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Publication number: 20190226967
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Application
    Filed: January 28, 2019
    Publication date: July 25, 2019
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Publication number: 20190170630
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Application
    Filed: June 6, 2018
    Publication date: June 6, 2019
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Patent number: 10222310
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: March 5, 2019
    Assignee: Theranos IP Company, LLC
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Patent number: 10018549
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: July 10, 2018
    Assignee: Theranos IP Company, LLC
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Patent number: 10012638
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: July 3, 2018
    Assignee: Theranos IP Company, LLC
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Publication number: 20170023594
    Abstract: Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 ?L) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.
    Type: Application
    Filed: May 27, 2016
    Publication date: January 26, 2017
    Inventors: Mark Dayel, Samartha Anekal, Paul Patel, Ian Gibbons, Elizabeth A. Holmes
  • Publication number: 20160341650
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Application
    Filed: April 19, 2016
    Publication date: November 24, 2016
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Patent number: 9500639
    Abstract: Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 ?L) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: November 22, 2016
    Assignee: Theranos, Inc.
    Inventors: Mark Dayel, Samartha Anekal, Paul Patel, Ian Gibbons, Elizabeth Holmes
  • Patent number: 9347867
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: May 24, 2016
    Assignee: Theranos, Inc.
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Publication number: 20150301018
    Abstract: Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 ?L) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.
    Type: Application
    Filed: January 16, 2015
    Publication date: October 22, 2015
    Inventors: Mark Dayel, Samartha Anekal, Paul Patel, Ian Gibbons, Elizabeth A. Holmes
  • Publication number: 20150233893
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Application
    Filed: February 20, 2015
    Publication date: August 20, 2015
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Publication number: 20150198515
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Application
    Filed: January 16, 2015
    Publication date: July 16, 2015
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Patent number: 8984932
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: March 24, 2015
    Assignee: Theranos, Inc.
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Publication number: 20140315240
    Abstract: Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.
    Type: Application
    Filed: June 30, 2014
    Publication date: October 23, 2014
    Inventors: Mark Dayel, Samartha Anekal, Elizabeth A. Holmes
  • Publication number: 20140087403
    Abstract: Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 ?L) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.
    Type: Application
    Filed: July 17, 2013
    Publication date: March 27, 2014
    Applicant: THERANOS, INC.
    Inventors: Mark Dayel, Samartha Anekal, Paul Patel, Ian Gibbons, Elizabeth Holmes