Patents by Inventor Mark Deem

Mark Deem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10945835
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having a first portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a valve support coupled to a second portion of the anchoring member, configured to support a prosthetic valve and having a cross-sectional shape. In some embodiments, the first portion of the anchoring member is mechanically isolated from the valve support such that the cross-sectional shape of the valve support remains sufficiently stable that the prosthetic valve remains competent when the anchoring member is deformed in the non-circular shape.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: March 16, 2021
    Assignee: TWELVE, INC.
    Inventors: John Morriss, Hanson Gifford, III, James I. Fann, Jean-Pierre Dueri, Matt McLean, Darin Gittings, Michael Luna, Mark Deem, Douglas Sutton, Jeffry J. Grainger
  • Patent number: 10898237
    Abstract: Pathology of the human spine can arise from excessive and/or uneven loading of regions within the spinal vertebrae and the intervertebral disc. Methods and apparatus are disclosed that enable displacement of soft tissue around the spine in a less invasive manner, thereby altering the mechanical load distribution within the spine to achieve a therapeutic effect.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: January 26, 2021
    Assignee: The Foundry, LLC
    Inventors: Vivek Shenoy, Hanson S. Gifford, III, Mark Deem
  • Patent number: 10874606
    Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: December 29, 2020
    Assignee: Mati Therapeutics Inc.
    Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
  • Patent number: 10850091
    Abstract: Methods and apparatus are provided for bilateral renal neuromodulation, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: December 1, 2020
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Denise Zarins, Hanson Gifford, III, Mark Deem, Douglas Sutton, Howard R. Levin, Mark Gelfand
  • Publication number: 20200368398
    Abstract: The devices, systems, and methods disclosed herein may be directed to a delivery system including a therapeutic member configured for endoluminal placement via the delivery system into the esophagus of the patient, wherein the therapeutic member comprises a treatment portion comprising a film for controlled release of a chemotherapeutic agent. The film may comprise a control region, a therapeutic region, and a substantially impermeable base region. The film is configured to release the chemotherapeutic agent in a direction away from the substantially impermeable base region. The delivery system is configured to enable a treatment provider to position the treatment portion of the therapeutic member proximate to a treatment site associated with the esophagus of the patient, and the therapeutic member is configured to administer a therapeutically effective dose to the treatment site for a sustained period following endoluminal placement of the therapeutic member.
    Type: Application
    Filed: January 8, 2019
    Publication date: November 26, 2020
    Inventors: Karun D. Naga, Stephen W. Boyd, Hanson S. Gifford, III, Mark Deem, John Morriss, Martin Mayse, Honglei Wang, Jingnan Luo, Daniel Boon Lim Seet, Koon Kiat Teu, Wei Li Lee
  • Publication number: 20200253583
    Abstract: An implantable ultrasonic vascular sensor for implantation at a fixed location within a vessel, comprising at least one ultrasound transducer, a transducer drive circuit, and means for wirelessly transmitting ultrasound data from the at least one ultrasound transducer.
    Type: Application
    Filed: May 31, 2018
    Publication date: August 13, 2020
    Inventors: Axel Brisken, Jessi Johnson, Douglas S. Sutton, Hanson S. Gifford, III, Mark Deem, Fiachra Sweeney
  • Patent number: 10702380
    Abstract: Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include a valve support having an upstream end and a downstream end extending around a longitudinal axis and having a cross-sectional shape. The valve support can have an outer surface and an inner surface, wherein the inner surface is configured to support a prosthetic valve. The device can also include an expandable retainer coupled to the upstream end of the valve support. The retainer can be configured to engage tissue on or near the annulus. In some embodiments, the valve support is mechanically isolated from the retainer such that the cross-sectional shape of the valve support remains sufficiently stable when the retainer is deformed in a non-circular shape by engagement with the tissue.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: July 7, 2020
    Assignee: Twelve, Inc.
    Inventors: John Morriss, Hanson Gifford, III, James L. Fann, Jean-Pierre Dueri, Darrin Gittings, Michael Luna, Mark Deem, Douglas Sutton
  • Patent number: 10695094
    Abstract: Pathology of the human knee can arise from excessive and/or uneven loading of regions within the joint. Methods and apparatus are disclosed that enable displacement of soft tissue around the knee, without displacing or severing bone thereby altering the mechanical load distribution within the joint in a less invasive manner than previous techniques.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: June 30, 2020
    Assignee: The Foundry, LLC
    Inventors: Vivek Shenoy, Hanson S. Gifford, III, Mark Deem
  • Publication number: 20200146664
    Abstract: A method of treating a patient's joint having opposing joint surfaces includes providing an elongate member having a proximal end, a distal end and an expandable member near the distal end. The expandable member is positioned in the joint between the joint surfaces and expanded so as to separate the joint surfaces away from one another into a distracted position. The joint is manipulated while in the distracted position so that the joint is distracted and in flexion. A diagnostic or therapeutic procedure is then performed on the joint while maintaining the joint in the flexed and distracted position.
    Type: Application
    Filed: November 12, 2019
    Publication date: May 14, 2020
    Inventors: David Boudreault, Vivek Shenoy, Hanson S. Gifford, Mark Deem, Michael Hendricksen, Doug Sutton
  • Patent number: 10603490
    Abstract: GI tract treatment and monitoring devices configured for temporary implantation in the GI tract and non-invasive removal via natural body processes are disclosed. Methods of implantation, treatment and monitoring with disclosed devices are also disclosed. Devices include bio-active fixation that allows removal from the body by natural processes after a time that may be engineered in the fixation elements. In some embodiments, devices are configured to be implanted on GI tract tissue and transmurally migrate into the GI tract to be passed from the body. In other embodiments, devices are configured for placement within the GI tract via a delivery tube such as an NJ/NG tube. Embodiments include stimulation devices for treating conditions such as ileus and sensors for monitoring GI leaks and/or biological or chemical markers for various GI tract conditions.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: March 31, 2020
    Assignee: The Foundry LLC
    Inventors: Hanson S. Gifford, III, Mark Deem
  • Patent number: 10588614
    Abstract: A knotless suture anchoring system includes an outer anchor having a central channel and a distal tip adapted to penetrate tissue. An inner anchor is positionable in the central channel of the outer anchor and a locking feature on one or both of the inner and outer anchors retains the inner anchor within the central channel. A continuous length of suture is coupled with the inner and outer suture anchors and has a free end. At least one of the inner and the outer anchors also has a cinching mechanism that allows the suture to be tensioned by passage of the suture through the cinching mechanism in a first direction while movement of the suture through the cinching mechanism in a second direction opposite the first direction is constrained.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: March 17, 2020
    Assignee: The Foundry, LLC
    Inventors: Darin C. Gittings, Mark Deem, Michael Hendricksen, Vivek Shenoy, Hanson S. Gifford, III, Stephen Boyd
  • Publication number: 20200000715
    Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.
    Type: Application
    Filed: August 19, 2019
    Publication date: January 2, 2020
    Applicant: Mati Therapeutics Inc.
    Inventors: Eugene de Juan, JR., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
  • Patent number: 10517725
    Abstract: Systems for mitral valve repair are disclosed where one or more mitral valve interventional devices may be advanced intravascularly into the heart of a patient and deployed upon or along the mitral valve to stabilize the valve leaflets. The interventional device may also facilitate the placement or anchoring of a prosthetic mitral valve implant. The interventional device may generally comprise a distal set of arms pivotably and/or rotating coupled to a proximal set of arms which are also pivotably and/or rotating coupled. The distal set of arms may be advanced past the catheter opening to a subannular position (e.g., below the mitral valve) and reconfigured from a low-profile delivery configuration to a deployed securement configuration. The proximal arm members may then be deployed such that the distal and proximal arm members may grip the leaflets between the two sets of arms to stabilize the leaflets.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: December 31, 2019
    Assignee: Twelve, Inc.
    Inventors: Hanson S. Gifford, III, James I. Fann, John Morriss, Mark Deem, Jeffry J. Grainger
  • Publication number: 20190374222
    Abstract: A method for impacting a suture anchor into bone comprises providing an implantable suture anchor and providing an impactor device for impacting the suture anchor into the bone. The suture anchor is coupled to a distal portion of the impactor device. Positioning the suture anchor engages the anchor with the bone at an implantation site, and powering the impactor device impacts the suture anchor thereby implanting the suture anchor into the bone. The frequency of impaction is less than 20 KHz. The impactor device is then decoupled from the suture anchor, and the impactor device may be removed from the implantation site.
    Type: Application
    Filed: August 19, 2019
    Publication date: December 12, 2019
    Inventors: Darin C. Gittings, Mark Deem, Hanson S. Gifford, Doug Sutton, Vivek Shenoy
  • Patent number: 10470754
    Abstract: A method of treating a patient's joint having opposing joint surfaces includes providing an elongate member having a proximal end, a distal end and an expandable member near the distal end. The expandable member is positioned in the joint between the joint surfaces and expanded so as to separate the joint surfaces away from one another into a distracted position. The joint is manipulated while in the distracted position so that the joint is distracted and in flexion. A diagnostic or therapeutic procedure is then performed on the joint while maintaining the joint in the flexed and distracted position.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: November 12, 2019
    Assignee: Pivot Medical, Inc.
    Inventors: David Boudreault, Vivek Shenoy, Hanson S. Gifford, Mark Deem, Michael Hendricksen, Doug Sutton
  • Patent number: 10441356
    Abstract: Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. In some embodiments, thermally-induced renal neuromodulation is achieved via delivery of a pulsed thermal therapy.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: October 15, 2019
    Assignee: MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.
    Inventors: Denise Zarins, Andrew Wu, Hanson Gifford, III, Mark Deem, Mark Gelfand, Howard R. Levin
  • Patent number: 10420606
    Abstract: Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: September 24, 2019
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Denise Zarins, Hanson Gifford, III, Mark Deem, Nicolas Zadno, Benjamin J. Clark, Andrew Wu, Kenneth J. Michlitsch
  • Publication number: 20190282816
    Abstract: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for extravascular delivery of pulsed electric fields to achieve such neuromodulation.
    Type: Application
    Filed: March 28, 2019
    Publication date: September 19, 2019
    Inventors: Mark Deem, Denise Zarins, Douglas Sutton, Hanson Gifford, III, Howard R. Levin, Mark Gelfand, Benjamin J. Clark
  • Patent number: 10383817
    Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: August 20, 2019
    Assignee: Mati Therapeutics Inc.
    Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S Gifford, Mark Deem
  • Patent number: 10383624
    Abstract: A method for impacting a suture anchor into bone comprises providing an implantable suture anchor and providing an impactor device for impacting the suture anchor into the bone. The suture anchor is coupled to a distal portion of the impactor device. Positioning the suture anchor engages the anchor with the bone at an implantation site, and powering the impactor device impacts the suture anchor thereby implanting the suture anchor into the bone. The frequency of impaction is less than 20 KHz. The impactor device is then decoupled from the suture anchor, and the impactor device may be removed from the implantation site.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: August 20, 2019
    Assignee: The Foundry, LLC
    Inventors: Darin C. Gittings, Mark Deem, Hanson S. Gifford, Doug Sutton, Vivek Shenoy