Patents by Inventor Mark DeNichilo

Mark DeNichilo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosing renal disorders
    Patent number: 8110367
    Abstract: The present invention relates to methods for diagnosing the presence and progress of pathologies characterized by an accumulation of the extracellular matrix components by measuring the level of Connective Tissue Growth Factor (CTGF) in a sample. The method of the present invention is directed to diagnosing kidney fibrosis and associated renal disorders, in particular, complications associated with diabetes, hyperglycemia, and hypertension.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: February 7, 2012
    Assignee: FibroGen, Inc.
    Inventors: Bruce L. Riser, Mark DeNichilo
  • Methods for diagnosing renal disorders
    Publication number: 20090017559
    Abstract: The present invention relates to methods for diagnosing the presence and progress of pathologies characterized by an accumulation of the extracellular matrix components by measuring the level of Connective Tissue Growth Factor (CTGF) in a sample. The method of the present invention is directed to diagnosing kidney fibrosis and associated renal disorders, in particular, complications associated with diabetes, hyperglycemia, and hypertension.
    Type: Application
    Filed: August 1, 2008
    Publication date: January 15, 2009
    Applicants: Henry Ford Health System, FibroGen, Inc.
    Inventors: Bruce L. Riser, Mark DeNichilo
  • Treatment of disorders associated with elevated blood glucose or blood pressure
    Publication number: 20050136502
    Abstract: The present invention relates to methods for treating or delaying the onset of pathologies associated with elevated blood glucose and/or elevated blood pressure. The methods are directed to modulating, regulating, or inhibiting the expression or activity of Connective Tissue Growth Factor (CTGF) or fragments thereof.
    Type: Application
    Filed: December 16, 2004
    Publication date: June 23, 2005
    Inventors: Bruce Riser, Mark DeNichilo
  • Methods for diagnosing renal disorders
    Publication number: 20040224360
    Abstract: The present invention relates to methods for diagnosing the presence and progress of pathologies characterized by an accumulation of the extracellular matrix components by measuring the level of Connective Tissue Growth Factor (CTGF) in a sample. The method of the present invention is directed to diagnosing kidney fibrosis and associated renal disorders, in particular, complications associated with diabetes, hyperglycemia, and hypertension.
    Type: Application
    Filed: October 16, 2003
    Publication date: November 11, 2004
    Inventors: Bruce L. Riser, Mark DeNichilo