Patents by Inventor Mark Denison

Mark Denison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Live attenuated coronavirus vaccines
    Patent number: 7452542
    Abstract: The present invention is directed live, attenuated coronavirus vaccines. The vaccine comprises a viral genome encoding a p59 protein having at mutation at a specific tyrosine residue, and may include other attenuating mutations. Such viruses show reduced growth and pathogenicity in vivo.
    Type: Grant
    Filed: May 23, 2005
    Date of Patent: November 18, 2008
    Assignee: Vanderbilt University
    Inventor: Mark Denison
  • Live Attenuated Nidovirus Vaccines
    Publication number: 20070286872
    Abstract: The present invention is directed live, attenuated Nidovirus vaccines, and in a particular embodiment, to coronavirus vaccines. The vaccine comprises a viral genome encoding a replicase polyprotein having at least one proteinase cleavage site that exhibits reduced or no cleavage. Such viruses show reduced.
    Type: Application
    Filed: April 22, 2004
    Publication date: December 13, 2007
    Applicant: Vanderbilt University
    Inventor: Mark Denison
  • Live attenuated Coronavirus vaccines
    Publication number: 20060039926
    Abstract: The present invention is directed live, attenuated coronavirus vaccines. The vaccine comprises a viral genome encoding a p59 protein having at mutation at a specific tyrosine residue, and may include other attenuating mutations. Such viruses show reduced growth and pathogenicity in vivo.
    Type: Application
    Filed: May 23, 2005
    Publication date: February 23, 2006
    Inventor: Mark Denison
  • Method of forming relief image having line width less than 0.35 microns utilizing copolymer binder having phenolic and nonaromatic cyclic alcohol units
    Patent number: 5368993
    Abstract: The present invention relates to photoresists particularly suitable for deep U.V. exposure and having the capability of forming highly resolved features. The invention is characterized by use of a resist resin binder that comprises a nonaromatic cyclic alcohol-phenol copolymer that has a relatively low molecular weight and narrow distribution of molecular weight and cyclic alcohol concentration.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: November 29, 1994
    Assignee: Shipley Company Inc.
    Inventors: James W. Thackeray, Mark Denison, George W. Orsula
  • Photoresist compositions with copolymer binder having phenolic and nonaromatic cyclic alcohol units where the distribution of the cyclic alcohol concentration is less than 8 mole percent
    Patent number: 5340696
    Abstract: The present invention relates to photoresists particularly suitable for deep U.V. exposure and having the capability of forming highly resolved features. The invention is characterized by use of a resist resin binder that comprises a nonaromatic cyclic alcohol-phenol copolymer that has a relatively low molecular weight and narrow distribution of molecular weight and cyclic alcohol concentration.
    Type: Grant
    Filed: January 29, 1993
    Date of Patent: August 23, 1994
    Assignee: Shipley Company Inc.
    Inventors: James W. Thackeray, Mark Denison, George W. Orsula