Abstract: The present disclosure relates to a vessel/tissue protection device having a polymer coated reinforcing layer. The polymer can comprise a biocompatible polymer that will not promote tissue in-growth or attachment, such as segmented polyurethane, polycarbonate urethane, polyether urethane, polyacrylonitrile, etc. The reinforcing layer can comprise any suitable woven, non-woven, knitted, or braided reinforcing polymer, fabric, or foil that is biocompatible and capable of holding a suture, staple, or other attachment device.