Patents by Inventor Mark Dolman

Mark Dolman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Boronic Acid Salts
    Publication number: 20100113393
    Abstract: Salts of a peptide boronic acid drug, for example of Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH)2. The counter-ion to the boronate may be an alkali metal or derived from a strongly basic organic nitrogen-containing compound.
    Type: Application
    Filed: June 9, 2009
    Publication date: May 6, 2010
    Inventors: David Jonathan Madge, Mark Dolman, John Joseph Deadman, Anthony James Kennedy, Sophie Marie Combe-Marzelle, Sanjay Kumar Kakkar
  • Multivalent metal salts of boronic acids
    Publication number: 20100035827
    Abstract: Salts of a pharmaceutically acceptable divalent metal and an organoboronic acid drug. Examples of such metals are calcium, magnesium and zinc. The organoboronic acid drug may be a boropeptide protease inhibitor. The salts may be formulated in oral dosage form.
    Type: Application
    Filed: February 26, 2009
    Publication date: February 11, 2010
    Inventors: John Joseph Deadman, David Jonathan Madge, Mark Dolman, Sanjay Kumar Kakkar, Anthony James Kennedy, Sophie Marie Combe-Marzelle, Suresh Babubhai Chahwala, Oliver Vimpany Arnold Boucher
  • Boronic Acid Salts Useful in Parenteral Formulations
    Publication number: 20080287370
    Abstract: Salts of a peptide boronic acid drug, for example of Cbz-(R)-Phe-(S)—Pro-(R)-Mpg-B(OH)2. The counter-ion to the boronate may be an alkali metal or derived from a strongly basic organic nitrogen-containing compound.
    Type: Application
    Filed: April 24, 2008
    Publication date: November 20, 2008
    Inventors: David Jonathan MADGE, Mark Dolman, Sophie Marie Combe-Marzelle, John Joseph Deadman, Anthony James Kennedy, Sanjay Kumar Kakkar
  • Boronic acid salts
    Publication number: 20080234228
    Abstract: Salts of a peptide boronic add drug, for example of Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH)2. The counter-ion to the boronate may be an alkali metal or derived from a strongly basic organic nitrogen-containing compound.
    Type: Application
    Filed: October 31, 2007
    Publication date: September 25, 2008
    Inventors: David Jonathan Madge, Mark Dolman, John Joseph Deadman, Anthony James Kennedy, Sophie Marie Combe-Marzelle, Sanjay Kumar Kakkar
  • Boronic acid salts useful in parenteral formulations
    Patent number: 7371729
    Abstract: Salts of a peptide boronic acid drug, for example of Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH)2. The counter-ion to the boronate may be an alkali metal or derived from a strongly basic organic nitrogen-containing compound.
    Type: Grant
    Filed: September 9, 2003
    Date of Patent: May 13, 2008
    Assignee: Trigen Limited
    Inventors: David Jonathan Madge, Mark Dolman, Sophie Marie Combe-Marzelle, John Joseph Deadman, Anthony James Kennedy, Sanjay Kumar Kakkar
  • Multivalent metal salts of boronic acids
    Publication number: 20060229257
    Abstract: Salts of a pharmaceutically acceptable divalent metal and an organoboronic acid drug. Examples of such metals are calcium, magnesium and zinc. The organoboronic acid drug may be a boropeptide protease inhibitor. The salts may be formulated in oral dosage form.
    Type: Application
    Filed: May 22, 2006
    Publication date: October 12, 2006
    Inventors: John Deadman, David Madge, Mark Dolman, Sanjay Kakkar, Anthony Kennedy, Sophie Combe-Marzelle, Suresh Chahwala, Oliver Vimpany Boucher
  • Multivalent metal salts of boronic acids
    Patent number: 7112572
    Abstract: Salts of a pharmaceutically acceptable divalent metal and an organoboronic acid drug. Examples of such metals are calcium, magnesium and zinc. The organoboronic acid drug may be a boropeptide protease inhibitor. The salts may be formulated in oral dosage form.
    Type: Grant
    Filed: September 9, 2003
    Date of Patent: September 26, 2006
    Assignee: Trigen Limited
    Inventors: John Joseph Deadman, David Jonathan Madge, Mark Dolman, Sanjay Kumar Kakkar, Anthony James Kennedy, Sophie Marie Combe-Marzelle, Suresh Babubhai Chahwala, Oliver Vimpany Arnold Boucher
  • Boronic acid salts
    Publication number: 20050288253
    Abstract: Salts of a peptide boronic acid drug, for example of Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH)2. The counter-ion to the boronate may be an alkali metal or derived from a strongly basic organic nitrogen-containing compound.
    Type: Application
    Filed: September 9, 2003
    Publication date: December 29, 2005
    Inventors: David Madge, Mark Dolman, John Deadman, Anthony Kennedy, Sophie Combe-Marzelle, Sanjay Kakkar
  • Peptide boronic acids useful in making salts thereof
    Publication number: 20050176651
    Abstract: Tripeptide boronic acids of (R,S,R) configuration, for example Cbz-(R)-Phe-(S)-Pro-(R)-Mpg-B(OH)2, and their use to make base addition salts of such acids. The salts are formulated into anti-thrombotic pharmaceutical formulations.
    Type: Application
    Filed: September 8, 2004
    Publication date: August 11, 2005
    Inventors: David Madge, Mark Dolman, Armin Walter, Dieter Krimmer, John Deadman, Alfred Olbrich, Andrea Weiland-Waibel
  • Multivalent metal salts of boronic acids
    Publication number: 20040147453
    Abstract: Salts of a pharmaceutically acceptable divalent metal and an organoboronic acid drug. Examples of such metals are calcium, magnesium and zinc. The organoboronic acid drug may be a boropeptide protease inhibitor. The salts may be formulated in oral dosage form.
    Type: Application
    Filed: September 9, 2003
    Publication date: July 29, 2004
    Applicant: Trigen Limited
    Inventors: John Joseph Deadman, David Jonathan Madge, Mark Dolman, Sanjay Kumar Kakkar, Anthony James Kennedy, Sophie Marie Combe-Marzelle, Suresh Babubhai Chahwala, Oliver Vimpany Arnold Boucher
  • Boronic acid salts useful in parenteral formulations
    Publication number: 20040138175
    Abstract: Salts of a peptide boronic acid drug, for example of Cbz—(R)—Phe—(S)—Pro—(R)—Mpg—B(OH)2. The counter-ion to the boronate may be an alkali metal or derived from a strongly basic organic nitrogen-containing compound.
    Type: Application
    Filed: September 9, 2003
    Publication date: July 15, 2004
    Applicant: Trigen Limited
    Inventors: David Jonathan Madge, Mark Dolman, Sophie Marie Combe-Marzelle, John Joseph Deadman, Anthony James Kennedy, Sanjay Kumar Kakkar