Patents by Inventor Mark Durst

Mark Durst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200057955
    Abstract: A system for modeling the evolution of a system over time using an advection-based process is provided. The system continuously evolves a probability density function (“PDF”) for a characteristic of a characteristic of the state of the system and its time-varying parameters. The PDF is evolved based on advection by solving an advection partial differential equation that is based on a system model of the system. The system model has time-varying parameters for modeling the characteristic of the state of the system. The system uses the continuously evolving PDF to make predictions out the characteristic of the state of the system.
    Type: Application
    Filed: March 8, 2019
    Publication date: February 20, 2020
    Inventors: David Balaban, Todd W. Kelley, John Scott Skellenger, Mark Durst, Michael Tupikov, Nicolas Sean Frisby, Dominic Joseph Steinitz
  • Publication number: 20070212678
    Abstract: A mechanistic model was developed to extract meaningful thermodynamic and kinetic parameters from an irreversibly denatured process. As a result, methods and computer apparatus have been created that can be used to mathematically determine parameters that are predictive of aggregation kinetics of biologically active materials. Those parameters can then be used to predict stability or aggregation kinetics as a function of time and temperature.
    Type: Application
    Filed: April 22, 2005
    Publication date: September 13, 2007
    Applicant: AMGEN INC.
    Inventors: Richard Remmele Jr, David Balaban, Jian Zhang, Alexander Shoshitaishvili, Mark Durst