Patents by Inventor Mark DYSINGER

Mark DYSINGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of quantitating unbound C5 in a sample
    Patent number: 11965884
    Abstract: A method of quantitating free (unbound) human C5 complement protein (C5) from a sample comprising: binding biotinylated anti-C5 capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: April 23, 2024
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Mark Dysinger, Mark Ma, Bruce A. Andrien
  • Method of quantitating unbound C5a in a sample
    Patent number: 11828683
    Abstract: A method of quantitating free (unbound) human C5a complement protein (C5a) from a sample comprising: binding biotinylated anti-C5a capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5a; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument; wherein human C5 is first removed from the sample.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: November 28, 2023
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Mark Dysinger, Mark Ma
  • A METHOD OF QUANTITATING UNBOUND C5 IN A SAMPLE
    Publication number: 20190250157
    Abstract: A method of quantitating free (unbound) human C5 complement protein (C5) from a sample comprising: binding biotinylated anti-C5 capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument.
    Type: Application
    Filed: October 19, 2017
    Publication date: August 15, 2019
    Inventors: Mark DYSINGER, Mark MA, Bruce A. ANDRIEN
  • A METHOD OF QUANTITATING UNBOUND C5A IN A SAMPLE
    Publication number: 20190242893
    Abstract: A method of quantitating free (unbound) human C5a complement protein (C5a) from a sample comprising: binding biotinylated anti-C5a capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5a; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument; wherein human C5 is first removed from the sample.
    Type: Application
    Filed: October 19, 2017
    Publication date: August 8, 2019
    Inventors: Mark DYSINGER, Mark MA