Patents by Inventor Mark E. DARIS

Mark E. DARIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEIC ACID ENCODING LILRB1-BASED CHIMERIC ANTIGEN RECEPTOR
    Publication number: 20230029341
    Abstract: Provided are polynucleotides comprising nucleic acid sequences encoding chimeric antigen receptors having the hinge, transmembrane region, and/or intracellular domain of LILRB1, or functional fragments or variants thereof. Also provided herein are vectors and immune cells comprising said polynucleotides.
    Type: Application
    Filed: December 11, 2020
    Publication date: January 26, 2023
    Inventors: Carl Alexander Kamb, Agnes E. Hamburger, Breanna Diandreth, Mark E. Daris, Kiran Deshmukh
  • LILRB1-BASED CHIMERIC ANTIGEN RECEPTOR
    Publication number: 20220289818
    Abstract: Provided are chimeric antigen receptors having the hinge, transmembrane region, and/or intracellular domain of LILRB1, or functional fragments or variants thereof. Also provided herein are cells comprising the LILRB1 based receptors, and methods of making and using same.
    Type: Application
    Filed: May 12, 2022
    Publication date: September 15, 2022
    Inventors: Carl Alexander Kamb, Agnes E. Hamburger, Breanna Diandreth, Mark E. Daris, Kiran Deshmukh
  • LILRB1-BASED CHIMERIC ANTIGEN RECEPTOR
    Publication number: 20220162287
    Abstract: Provided are chimeric antigen receptors having the hinge, transmembrane region, and/or intracellular domain of LILRB1, or functional fragments or variants thereof. Also provided herein are cells comprising the LILRB1 based receptors, and methods of making and using same.
    Type: Application
    Filed: January 31, 2022
    Publication date: May 26, 2022
    Inventors: Carl Alexander KAMB, Agnes E. HAMBURGER, Breanna DIANDRETH, Mark E. DARIS, Kiran DESHMUKH
  • LILRB1-BASED CHIMERIC ANTIGEN RECEPTOR
    Publication number: 20220153807
    Abstract: Provided are chimeric antigen receptors having the hinge, transmembrane region, and/or intracellular domain of LILRB1, or functional fragments or variants thereof. Also provided herein are cells comprising the LILRB1 based receptors, and methods of making and using same.
    Type: Application
    Filed: January 31, 2022
    Publication date: May 19, 2022
    Inventors: Carl Alexander KAMB, Agnes E. HAMBURGER, Breanna DIANDRETH, Mark E. DARIS, Kiran DESHMUKH
  • LILRB1-based chimeric antigen receptor
    Patent number: 11254726
    Abstract: Provided are chimeric antigen receptors having the hinge, transmembrane region, and/or intracellular domain of LILRB1, or functional fragments or variants thereof. Also provided herein are cells comprising the LILRB1 based receptors, and methods of making and using same.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: February 22, 2022
    Assignee: A2 Biotherapeutics, Inc.
    Inventors: Carl Alexander Kamb, Agnes E. Hamburger, Breanna Diandreth, Mark E. Daris, Kiran Deshmukh
  • LILRB1-BASED CHIMERIC ANTIGEN RECEPTOR
    Publication number: 20210230247
    Abstract: Provided are chimeric antigen receptors having the hinge, transmembrane region, and/or intracellular domain of LILRB1, or functional fragments or variants thereof. Also provided herein are cells comprising the LILRB1 based receptors, and methods of making and using same.
    Type: Application
    Filed: April 14, 2021
    Publication date: July 29, 2021
    Inventors: Carl Alexander KAMB, Agnes E. HAMBURGER, Breanna DIANDRETH, Mark E. DARIS, Kiran DESHMUKH