Patents by Inventor Mark E. Davis

Mark E. Davis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11285212
    Abstract: Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a nitroboronic boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing the nitroboronic acid to an environment external to the nanoparticle. Targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: March 29, 2022
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Han Han
  • Publication number: 20220062875
    Abstract: This disclosure describes enantiomerically enriched chiral molecular sieves and methods of making and using the same. In some embodiments, the molecular sieves are silicates or germanosilicates of STW topology.
    Type: Application
    Filed: November 10, 2021
    Publication date: March 3, 2022
    Inventors: Mark E. Davis, Stephen Kramer Brand, Joel E. Schmidt, Michael W. Deem
  • Patent number: 11213809
    Abstract: The present disclosure is directed to novel germanosilicate compositions and methods of producing and using the same. In particular, this disclosure describes new germanosilicates of CIT-14 topology. The disclosure also describes methods of preparing and using these new germanosilicate compositions as well as the compositions themselves.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: January 4, 2022
    Assignees: California Institute of Technology, Chevron U.S.A., Inc.
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang, Dan Xie
  • Patent number: 11213807
    Abstract: The present disclosure is directed to novel germanosilicate compositions and methods of producing the same. In particular, this disclosure describes new silica-rich compositions of the germanosilicate designated CIT-13, with and without added metal oxides. The disclosure also describes methods of preparing and using these new germanosilicate compositions as well as the compositions themselves.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: January 4, 2022
    Assignee: California Institute of Technology
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang
  • Patent number: 11213808
    Abstract: The present disclosure is directed to novel germanosilicate compositions and methods of producing and using the same. Included among the new materials are the new germanosilicates of CIT-5 topology having Si:Ge ratios either in a range of from 3.8 to 5.4 or from 30 to 200, with and without added metal oxides. The disclosure also describes methods of preparing and using these new germanosilicate compositions as well as the compositions themselves.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: January 4, 2022
    Assignee: California Institute of Technology
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang
  • Patent number: 11207665
    Abstract: The present disclosure is directed to novel phyllosilicate compositions designated CIT-13P and methods of producing and using the same.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: December 28, 2021
    Assignee: California Institute of Technology
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang
  • Patent number: 11203013
    Abstract: This disclosure describes enantiomerically enriched chiral molecular sieves and methods of making and using the same. In some embodiments, the molecular sieves are silicates or germanosilicates of STW topology.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: December 21, 2021
    Assignees: California Institute of Technology, William Marsh Rice University
    Inventors: Mark E. Davis, Stephen Kramer Brand, Joel E. Schmidt, Michael W. Deem
  • Publication number: 20210346874
    Abstract: The present disclosure is directed to methods of producing zincoaluminosilicate structures with AEI, CHA, and GME topologies using organic structure directing agents (OSDAs), and the compositions and structures resulting from these methods.
    Type: Application
    Filed: July 16, 2021
    Publication date: November 11, 2021
    Inventors: Michiel J. Dusselier, Mark E. Davis
  • Patent number: 11167276
    Abstract: The present disclosure is directed to methods of producing zincoaluminosilicate structures with AEI, CHA, and GME topologies using organic structure directing agents (OSDAs), and the compositions and structures resulting from these methods.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: November 9, 2021
    Assignee: California Institute of Technology
    Inventors: Michiel J. Dusselier, Mark E. Davis
  • Patent number: 11167275
    Abstract: The present disclosure is directed to producing zeolite structures with GME topologies using organic structure directing agents (OSDAs) comprising a piperidinium cation, and the compositions and structures resulting from these methods. In some embodiments, the crystalline products have a molar ratio of a molar ratio of Si:Al that is greater than 3.5.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: November 9, 2021
    Assignee: California Institute of Technology
    Inventors: Michiel J. Dusselier, Mark E. Davis
  • Publication number: 20210283258
    Abstract: Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a nitroboronic boronic acid and a linkage cleavable under reducing conditions, configured to present the polymer containing the nitroboronic acid to an environment external to the nanoparticle. Targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems.
    Type: Application
    Filed: May 20, 2021
    Publication date: September 16, 2021
    Inventors: Mark E. Davis, Han Han
  • Publication number: 20210261739
    Abstract: The present disclosure is directed to nanoparticle delivery systems for delivering biological agents, pharmaceutical compositions of comprising these nanoparticles, and methods of using these compositions. Certain embodiments of the present disclosure provide nanoparticles comprising polymers comprising alternating charged and uncharged segments comprising one or more of the following structural units of Formula (I) Formula (III): wherein A is an uncharged segment comprising polyalkylene glycol; and B is a cationically charged segment comprising at least one polyhydroxy linkage.
    Type: Application
    Filed: May 5, 2021
    Publication date: August 26, 2021
    Inventors: Mark E. Davis, Dorothy Pan
  • Publication number: 20210220483
    Abstract: The present application discloses nanoparticles carrying therapeutic agents, including chemotherapeutic agents, and targeting ligands suitable for delivering these therapeutic agents through the blood brain barrier and methods of using these patients on those patients in need of such treatment.
    Type: Application
    Filed: March 29, 2021
    Publication date: July 22, 2021
    Inventors: Mark E. Davis, Emily A. Wyatt
  • Patent number: 11041050
    Abstract: The present disclosure is directed to nanoparticle delivery systems for delivering biological agents, pharmaceutical compositions of comprising these nanoparticles, and methods of using these compositions. Certain embodiments of the present disclosure provide nanoparticles comprising polymers comprising alternating charged and uncharged segments comprising one or more of the following structural units of Formula (I) Formula (III): wherein A is an uncharged segment comprising polyalkylene glycol; and B is a cationically charged segment comprising at least one polyhydroxy linkage.
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: June 22, 2021
    Assignee: California Institute of Technology
    Inventors: Mark E. Davis, Dorothy Pan
  • Publication number: 20210154648
    Abstract: The present disclosure is directed to novel germanosilicate compositions and methods of producing the same. In particular, this disclosure describes new silica-rich compositions of the germanosilicate designated CIT-13, with and without added metal oxides. The disclosure also describes methods of preparing and using these new germanosilicate compositions as well as the compositions themselves.
    Type: Application
    Filed: January 13, 2021
    Publication date: May 27, 2021
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang
  • Publication number: 20210154649
    Abstract: The present disclosure is directed to novel phyllosilicate compositions designated CIT-13P and methods of producing and using the same.
    Type: Application
    Filed: January 13, 2021
    Publication date: May 27, 2021
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang
  • Publication number: 20210154308
    Abstract: Described herein is a cyclodextrin containing polymer conjugate.
    Type: Application
    Filed: June 25, 2020
    Publication date: May 27, 2021
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-jou Lim, Thomas Schluep
  • Publication number: 20210129120
    Abstract: The present disclosure is directed to novel germanosilicate compositions and methods of producing and using the same. In particular, this disclosure describes new germanosilicates of CIT-14 topology. The disclosure also describes methods of preparing and using these new germanosilicate compositions as well as the compositions themselves.
    Type: Application
    Filed: January 13, 2021
    Publication date: May 6, 2021
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang, Dan Xie
  • Publication number: 20210128516
    Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
    Type: Application
    Filed: January 8, 2021
    Publication date: May 6, 2021
    Inventors: Jianjun Cheng, Mark E. Davis, Kay T. Khin
  • Publication number: 20210129119
    Abstract: The present disclosure is directed to novel germanosilicate compositions and methods of producing and using the same. Included among the new materials are the new germanosilicates of CIT-5 topology having Si:Ge ratios either in a range of from 3.8 to 5.4 or from 30 to 200, with and without added metal oxides. The disclosure also describes methods of preparing and using these new germanosilicate compositions as well as the compositions themselves.
    Type: Application
    Filed: January 13, 2021
    Publication date: May 6, 2021
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang