Patents by Inventor Mark E. O'MALLEY

Mark E. O'MALLEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOSOMAL RECESSIVE CONGENITAL ICHTHYOSIS
    Publication number: 20230338444
    Abstract: The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding a transglutaminase (TGM) polypeptide (e.g., a Transglutaminase-1 (TGM1) polypeptide); viruses comprising the recombinant nucleic acids; compositions comprising the recombinant nucleic acids and/or viruses; methods of their use; and articles of manufacture or kits thereof.
    Type: Application
    Filed: June 15, 2023
    Publication date: October 26, 2023
    Applicant: Krystal Biotech, Inc.
    Inventors: Suma KRISHNAN, Pooja AGARWAL, John C. FREEDMAN, Mark E. O'MALLEY, Lauren K. REGULA
  • Compositions and methods for the treatment of autosomal recessive congenital ichthyosis
    Patent number: 11717547
    Abstract: The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding a transglutaminase (TGM) polypeptide (e.g., a Transglutaminase-1 (TGM1) polypeptide); viruses comprising the recombinant nucleic acids; compositions comprising the recombinant nucleic acids and/or viruses; methods of their use; and articles of manufacture or kits thereof.
    Type: Grant
    Filed: January 3, 2020
    Date of Patent: August 8, 2023
    Assignee: Krystal Biotech, Inc.
    Inventors: Suma Krishnan, Pooja Agarwal, John C. Freedman, Mark E. O'Malley, Lauren K. Regula
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOSOMAL RECESSIVE CONGENITAL ICHTHYOSIS
    Publication number: 20200197456
    Abstract: The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding a transglutaminase (TGM) polypeptide (e.g., a Transglutaminase-1 (TGM1) polypeptide); viruses comprising the recombinant nucleic acids; compositions comprising the recombinant nucleic acids and/or viruses; methods of their use; and articles of manufacture or kits thereof.
    Type: Application
    Filed: January 3, 2020
    Publication date: June 25, 2020
    Applicant: Krystal Biotech, Inc.
    Inventors: Suma KRISHNAN, Pooja AGARWAL, John C. FREEDMAN, Mark E. O'MALLEY, Lauren K. REGULA
  • Compositions and methods for the treatment of autosomal recessive congenital ichthyosis
    Patent number: 10525090
    Abstract: The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding a transglutaminase (TGM) polypeptide (e.g., a Transglutaminase-1 (TGM1) polypeptide); viruses comprising the recombinant nucleic acids; compositions comprising the recombinant nucleic acids and/or viruses; methods of their use; and articles of manufacture or kits thereof.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: January 7, 2020
    Assignee: Krystal Biotech, Inc.
    Inventors: Suma Krishnan, Pooja Agarwal, John C. Freedman, Mark E. O'Malley, Lauren K. Regula
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOSOMAL RECESSIVE CONGENITAL ICHTHYOSIS
    Publication number: 20190314430
    Abstract: The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding a transglutaminase (TGM) polypeptide (e.g., a Transglutaminase-1 (TGM1) polypeptide); viruses comprising the recombinant nucleic acids; compositions comprising the recombinant nucleic acids and/or viruses; methods of their use; and articles of manufacture or kits thereof.
    Type: Application
    Filed: April 11, 2019
    Publication date: October 17, 2019
    Applicant: Krystal Biotech, Inc.
    Inventors: Suma KRISHNAN, Pooja AGARWAL, John C. FREEDMAN, Mark E. O'MALLEY, Lauren K. REGULA