Patents by Inventor Mark E. Smulson

Mark E. Smulson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting a predisposition to cancer by detecting a deletion polymorphism in the gene for human poly (ADP-ribose) polymerase
    Patent number: 5449605
    Abstract: The invention relates to a method for detecting the presence of a DNA deletion polymorphism associated with susceptibility for cancer in a human using allele specific amplification primers. Disclosed herein are methods for analyzing human DNA using a hybridization probe which will identify a restriction fragment length polymorphism within the 13q33.fwdarw.qter locus, methods for selectively amplifying DNA within this locus, methods of identifying and producing or purifying the peptide encoded by the human poly (ADP-ribose) polymerase processed pseudogene, and methods of regulating the expression of said processed pseudogene.
    Type: Grant
    Filed: April 6, 1993
    Date of Patent: September 12, 1995
    Assignee: Georgetown University
    Inventors: Mark E. Smulson, Deborah Lyn, Barry Cherney
  • Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
    Patent number: 5272057
    Abstract: The invention relates to a method for detecting the presence of a DNA polymorphism associated with predisposition for certain cancers in a human. This method involves analyzing the human chromosome 13 using a hybridization probe which will hybridize to the gene for human poly (ADP-ribose) polymerase wherein the probe is capable of identifying the DNA polymorphism.
    Type: Grant
    Filed: October 14, 1988
    Date of Patent: December 21, 1993
    Assignee: Georgetown University
    Inventors: Mark E. Smulson, Kishor Bhatia, Konrad Huppi