Abstract: The present disclosure generally pertains to a device and system for preventing urinary backflow into the urinary tract of a patient. The device comprises a one-way valve which allows for unobstructed urine flow in the direction of the urine towards the urine collection container and away from the catheter. The device prevents backflow into the catheter in situations where the urine collection container is raised above the level of the bladder. The components on the exit side of the valve are coated with an antimicrobial substance to prevent bacterial contamination of the system. The exit volume also contains a silver coated high surface area element to serve as an antibacterial kill site. The inlet side of the device has a volume and access port for urine sampling, with a one-way valve element providing isolation from contamination from the urine collection system.