Patents by Inventor Mark Efimovich Volpin

Mark Efimovich Volpin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Agent for suppressing tumor growth
    Patent number: 6004953
    Abstract: The invention relates to the field of biology and medicine, in particular to suppression of the growth of malignant tumors.The object of the present invention is to find more effective and less toxic drugs for suppression of tumor growth.The essence of the proposed invention is that in order to suppress tumor growth, a drug consisting of a biogenic reductant and a complex of cobalt or iron with substituted phthalocyanines (I) or naphthalocyanines (II) is used. ##STR1## where R.dbd.COONa, SO.sub.3 Na, CH.sub.2 C.sub.5 H.sub.5 N.sup..sym. Cl.sup.-, CH.sub.2 (NH.sub.2).sub.2 S.sup..sym. CCl.sup.-.Use of the proposed drug makes it possible to suppress effectively the growth of a wide range of malignant tumors, in particular to achieve the suppression of proliferation of cancer cells (in vitro), inhibition of the growth of tumors in mice (in vivo) and a substantial increase in their life-span, including that obtained in comparison with use of the prototype.
    Type: Grant
    Filed: May 27, 1997
    Date of Patent: December 21, 1999
    Assignees: Institut Elementoorganicheskikh Soedineny Rossiiskoi Akademii Nauk, Gosudarsvenny Nauchy Tsentr Rossiiskoi Federatsii "Niopik", Onkologichesky Nauchy Tsentr Rossiiskoi Akademii Nauk, Moskovsky Naucho-Issledovatelsky Onkologichesky Institut
    Inventors: Mark Efimovich Volpin, deceased, Georgy Nikolaevich Vorozhtsov, Nadezhda Jurievna Krainova, Ilya Yakovlevich Levitin, Jury Mikhailovich Luzhkov, Evgeny Antonovich Lukiyanets, Galina Konstantinovna Gerasimova, Olga Stepanovna Zhukova, Natalya Ivanovna Kazachkina, Oleg Leonidovich Kalia, Nikolaevna Novodarova Galina, deceased, Elena Mikhailovna Treschalina, Anatoly Borisovich Syrkin, Valery Ivanovich Chissov, Raisa Ivanovna Yakubovskaya
  • Process for producing synthetic diamonds
    Patent number: 4085196
    Abstract: A process for producing synthetic diamonds which comprises the synthesis of diamonds from a charge consisting of graphite or a carbonaceous material capable of being graphitized and a catalyst; as the latter use is made of a metalgraphite laminar compound of a transition metal, wherein said metal is interposed between the graphite layers and chemically bonded therewith.Said catalyst makes it possible to shorten the duration of the synthesis down to several seconds and carry-out the synthesis at a temperature of below 1,200.degree. C. The resulting diamond crystals are colorless and transparent.
    Type: Grant
    Filed: February 28, 1977
    Date of Patent: April 18, 1978
    Inventors: Vladimir Ivanovich Farafontov, Yaroslav Alexeevich Kalashnikov, Jury Nikolaevich Novikov, Mark Efimovich Volpin, Leonid Fedorovich Vereschagin, Vladislav Sergeevich Lysanov