Abstract: A system for insurance underwriting and post policy issuance action comprising obtaining personal, medical, and genetic information for an applicant and determining the applicant's eligibility for an insurance policy is provided. The applicant may additionally be provided with information regarding genetic testing for alpha-1 antitrypsin deficiency or with information regarding testing of circulating AAT levels. Furthermore, alpha-1 antitrypsin testing may be ordered for the applicant as part of the insurance underwriting process or for the insured following policy acceptance or issuance.

Abstract: A method of preventing and/or treating a plurality of diseases by determining if the patient is alpha-1 antitrypsin deficient by obtaining a biological sample from the patient and performing a genotyping assay on the biological sample to determine if the patient has a SERPINA1 alpha-1 antitrypsin deficient genotype or measuring the circulating level of alpha-1 antitrypsin in the sample. If the patient has a SERPINA1 alpha-1 antitrypsin deficient genotype or low levels of circulating alpha-1 antitrypsin, then alpha-1 antitrypsin is administered to the patient.

Abstract: An early warning system having a plurality of vehicles, a plurality of smart phones, a plurality of signals and a command center which are electronically in communication with one another. Each vehicle, smart phone and signal which is part of the system has at least one receiver, sensor, processor, controller, transmitter and software. As a first vehicle approaches a second vehicle, a signal or a pedestrian carrying a smart phone, the transmitter connected to the second vehicle, a signal or a pedestrian sends information about the second vehicle, signal or pedestrian to the first vehicle. The first vehicle's processor process that information pursuant to the software and determines whether a hazard condition exists. In the event that a hazard condition exists, a warning device alarms the driver as to the existence of the hazard thereby helping the driver to avoid an accident and preventing property and personal injury.