Abstract: A confectionary item dispenser include a dispenser housing having a dispenser housing opening, a reservoir within the dispenser housing having a reservoir chute aligned with the dispenser housing opening, and a dispenser shield disposed within the dispenser housing and movable so that a dispenser shield opening can align with the dispenser housing opening and the reservoir chute at a dispensing position to dispense a confectionary item. An indeterminate outcome actuation mechanism with an actuation mechanism input device causes the dispenser shield to move between the dispensing position and a non-dispensing position when the actuation mechanism input device is displaced such that the dispenser shield may be disposed in one of the dispensing position and the non-dispensing position when the actuation mechanism input device is displaced so that a confectionary item may or may not be dispensed each time.

Abstract: A confectionary item dispenser include a dispenser housing having a dispenser housing opening, a reservoir within the dispenser housing having a reservoir chute aligned with the dispenser housing opening, and a dispenser shield disposed within the dispenser housing and movable so that a dispenser shield opening can align with the dispenser housing opening and the reservoir chute at a dispensing position to dispense a confectionary item. An indeterminate outcome actuation mechanism with an actuation mechanism input device causes the dispenser shield to move between the dispensing position and a non-dispensing position when the actuation mechanism input device is displaced such that the dispenser shield may be disposed in one of the dispensing position and the non-dispensing position when the actuation mechanism input device is displaced so that a confectionary item may or may not be dispensed each time.

Abstract: A candy dispenser include a dispenser housing having a dispenser housing opening, a candy reservoir within the dispenser housing having a candy reservoir chute aligned with the dispenser housing opening, and a dispenser shield disposed within the dispenser housing and movable so that a dispenser shield opening can align with the dispenser housing opening and the candy reservoir chute at a dispensing position to dispense a candy piece. An indeterminate outcome actuation mechanism with an actuation mechanism input device causes the dispenser shield to move between the dispensing position and at least one non-dispensing position when the actuation mechanism input device is displaced such that the dispenser shield may be disposed in any one of the dispensing position and the non-dispensing positions when the actuation mechanism input device is displaced so that a candy piece may or may not be dispensed each time.

Abstract: A candy dispenser include a dispenser housing having a dispenser housing opening, a candy reservoir within the dispenser housing having a candy reservoir chute aligned with the dispenser housing opening, and a dispenser shield disposed within the dispenser housing and movable so that a dispenser shield opening can align with the dispenser housing opening and the candy reservoir chute at a dispensing position to dispense a candy piece. An indeterminate outcome actuation mechanism with an actuation mechanism input device causes the dispenser shield to move between the dispensing position and at least one non-dispensing position when the actuation mechanism input device is displaced such that the dispenser shield may be disposed in any one of the dispensing position and the non-dispensing positions when the actuation mechanism input device is displaced so that a candy piece may or may not be dispensed each time.

Abstract: Skin equivalents and processes for preparing them are described. The living skin equivalent comprises a layer of cultured keratinocyte cells, a layer of high purity, non-porous collagen and a dermal layer of cultured fibroblast cells in a porous, cross-linked collagen sponge. Processes are described for producing the skin equivalent with descriptions on how to obtain and treat skin precursor materials to yield suitable fibroblasts and keratinocytes.The collagen layers, the physical forms thereof, and treatments thereof are also described. Preferably, the non-porous, highly-purified collagen is selected from Type 1, Type 3, or mixtures of Type 1 and Type 3 collagen. The collagen is purified ideally by treatment with pepsin, to remove antigenic substances.The collagen sponge used can be any suitable form of collagen sponge which will support fibroblast growth.The keratinocytes used in the invention are preferably prepared by the "drop" method spotted evenly on culture media and incubated to coalescence.

Abstract: A composite living skin equivalent is described comprising an epidermal layer of cultured keratinocyte cells, a layer of non-porous collagen, and a dermal layer of cultured fibroblast cells in a porous cross-linked collagen sponge matrix. Preferably the non-porous collagen is Type 1, Type 3 or mixtures of Types 1 and 3 bovine collagen, which has been pepsin treated. A process for preparing the skin equivalent is described, as well as a test kit for in vitro testing of the skin equivalent. The skin equivalent has use for skin grafting as well as in vitro testing of the effects of various substances on skin.

Abstract: A composite living skin equivalent is described comprising an epidermal layer of cultured keratinocyte cells, a layer of non-porous collagen, and a dermal layer of cultured fibroblast cells in a porous cross-linked collagen sponge matrix. Preferably the non-porous collagen is Type 1, Type 3 or mixtures of Types 1 and 3 bovine collagen, which has been pepsin treated. A process for preparing the skin equivalent is described, as well as a test kit for in vitro testing of the skin equivalent. The skin equivalent has use for skin grafting as well as in vitro testing of the effects of various substances on skin.The questions raised in reexamination request No. 90/003,418, filed Apr. 25, 1994, have been considered and the results thereof are reflected in this reissue patent which constitutes the reexamination certificate required by 35 U.S.C. 307 as provided in 37 CFR 1.570(e).