Patents by Inventor Mark Ellisman

Mark Ellisman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11965840
    Abstract: An epoxy resin-based embedding media doped with a non-conductive dopant to a predetermined w/w % such that the media is non-charging at 1.8 keV. A preferred dopant is polyethylene glycol at a molecular weight of at least 3350, and having a predetermined w/w % is at least 2% and up to 20%, most preferably from 2% to 10%. Another preferred dopant is polyethylene glycol at a molecular weight of 7000-8000 and a predetermined w/w % of up to ˜40% and more preferably of up to ˜30%.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: April 23, 2024
    Assignee: The Regents of the University of California
    Inventors: Thomas Deerinck, Mark Ellisman, Steven Peltier
  • Publication number: 20230375536
    Abstract: Methods and compositions provide for transfer of a detectable label, such as a photosensitizer, directly from a polypeptide of interest to an acceptor target molecule located in close proximity to the polypeptide of interest, facilitating detection of the target molecule. A multifunctional conjugation reagent is configured to provide such transfer.
    Type: Application
    Filed: May 15, 2023
    Publication date: November 23, 2023
    Inventors: Guillaume Castillon, Stephen Adams, Mark Ellisman, Daniela Boassa
  • Publication number: 20210333177
    Abstract: An epoxy resin-based embedding media doped with a non-conductive dopant to a predetermined w/w % such that the media is non-charging at 1.8 keV. A preferred dopant is polyethylene glycol at a molecular weight of at least 3350, and having a predetermined w/w % is at least 2% and up to 20%, most preferably from 2% to 10%. Another preferred dopant is polyethylene glycol at a molecular weight of 7000-8000 and a predetermined w/w % of up to ˜40% and more preferably of up to ˜30%.
    Type: Application
    Filed: April 23, 2021
    Publication date: October 28, 2021
    Inventors: Thomas Deerinck, Mark Ellisman, Steven Peltier
  • Publication number: 20060169901
    Abstract: A preferred method for transmission electron microscopy includes a step of generating a microscopy signal. The microscopy signal is then detected with an active pixel detector that includes a plurality of pixels. Each of the pixels includes at least one photodiode. Each pixel integrates an incident signal over a collection time period. Using a massibel parallel on chip analog to digital conversion, very fast read out times can be achieved, e.g., many frames per second. In a preferred embodiment, the read out time permits there to be a single electron event recorded per pixel, indicating either a single electron or the lack thereof. This permits simple accumulation of the pixel counts for each pixel in read-out and storage electronics.
    Type: Application
    Filed: December 6, 2005
    Publication date: August 3, 2006
    Inventors: Xuong Nguyen-Huu, Mark Ellisman, Stuart Kleinfelder