Patents by Inventor Mark Emptage
Mark Emptage has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190169585Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.Type: ApplicationFiled: February 14, 2019Publication date: June 6, 2019Inventors: Benjamin Bower, Mark Emptage, William D. Hitz, Megan Yee Hsi, Thijs Kaper, Bradley R. Kelemen, Steven Kim, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Keith Dumont Wing
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Patent number: 10273465Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.Type: GrantFiled: July 27, 2015Date of Patent: April 30, 2019Assignee: DANISCO US INC.Inventors: Benjamin Bower, Megan Yee Hsi, Thijs Kaper, Bradley R. Kelemen, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Steven Kim, William D. Hitz, Mark Emptage, Keith Dumont Wing
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Publication number: 20160177279Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.Type: ApplicationFiled: July 27, 2015Publication date: June 23, 2016Applicant: DANISCO US INC.Inventors: Benjamin BOWER, Megan Yee HSI, Thijs KAPER, Bradley R. KELEMEN, Suzanne E. LANTZ, Edmund A. LARENAS, Colin MITCHINSON, Steven KIM, William D. HITZ, Mark EMPTAGE, Keith Dumont WING
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Publication number: 20130177947Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.Type: ApplicationFiled: September 22, 2010Publication date: July 11, 2013Applicant: DANISCO US INC.Inventors: Benjamin Bower, Megan Yee Hsi, Thijs Kaper, Bradley R. Keleman, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Steven Kim, William D. Hitz, Mark Emptage, Keith Dumont Wing
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Patent number: 8465961Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.Type: GrantFiled: July 3, 2012Date of Patent: June 18, 2013Assignees: E I du Pont de Nemours and CompanyInventors: Perry G Caimi, Mark Emptage, Xu Li, Paul V Viitanen, Yat-Chen Chou, Mary Ann Franden, Min Zhang
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Publication number: 20120276607Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.Type: ApplicationFiled: July 3, 2012Publication date: November 1, 2012Applicant: E. I. DU PONT DE NEMOURS AND COMPANY & ALLIANCE FOR SUSTAINABLE ENERGY LLCInventors: PERRY G. CAIMI, MARK EMPTAGE, XU LI, PAUL V. VIITANEN, YAT-CHEN CHOU, MARY ANN FRANDEN, MIN ZHANG
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Patent number: 8247208Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.Type: GrantFiled: December 18, 2009Date of Patent: August 21, 2012Assignees: E I du Pont de Nemours and CompanyInventors: Perry G. Caimi, Mark Emptage, Xu Li, Paul V. Viitanen, Yat-Chen Chou, Mary Ann Franden, Min Zhang
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Publication number: 20110014670Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.Type: ApplicationFiled: December 18, 2009Publication date: January 20, 2011Applicant: E.I. DU PONT DE NEMOURS AND COMPANY & ALLIANCE FOR SUSTAINABLE ENERGY LLCInventors: PERRY G. CAIMI, Mark Emptage, Xu Li, Paul V. Viitanen, Yat-Chen Chou, Mary Ann Franden, Min Zhang
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Patent number: 7741084Abstract: Production of ethanol using a strain of xylose-utilizing Zymomonas with a genetic modification of the glucose-fructose oxidoreductase gene was found to be improved due to greatly reduced production of xylitol, a detrimental by-product of xylose metabolism synthesized during fermentation.Type: GrantFiled: September 27, 2007Date of Patent: June 22, 2010Assignees: E. I. du Pont de Nemours and Company, Alliance for Sustainable Energy LLCInventors: Paul V. Viitanen, Carol M. McCutchen, Mark Emptage, Perry G. Caimi, Min Zhang, Yat-Chen Chou
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Patent number: 7629156Abstract: Xylose-utilizing Z. mobilis strains were found to have improved ethanol production when grown in medium containing mixed sugars including xylose if sorbitol or mannitol was included in the medium. The effect was seen in concentrations of mixed sugars where no growth lag period occurs, as well as in higher sugars concentrations.Type: GrantFiled: September 27, 2007Date of Patent: December 8, 2009Assignees: E.I. du Pont de Nemours and Company, Alliance For Sustainable Energy, LLCInventors: Paul V. Viitanen, Carol M. Mc Cutchen, Xu Li, Mark Emptage, Perry G. Caimi, Min Zhang, Yat-Chen Chou, Mary Ann Franden
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Publication number: 20090253192Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).Type: ApplicationFiled: February 16, 2009Publication date: October 8, 2009Applicant: E. I. DU PONT DE NEMOURS AND COMPANYInventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend
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Patent number: 7504250Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).Type: GrantFiled: January 16, 2006Date of Patent: March 17, 2009Assignee: E. I. du Pont de Nemours and CompanyInventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Whited
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Patent number: 7452710Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).Type: GrantFiled: February 13, 2006Date of Patent: November 18, 2008Assignee: E.I. du Pont de Nemours and CompanyInventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Whited
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Publication number: 20080187973Abstract: Production of ethanol using a strain of xylose-utilizing Zymomonas with a genetic modification of the glucose-fructose oxidoreductase gene was found to be improved due to greatly reduced production of xylitol, a detrimental by-product of xylose metabolism synthesized during fermentation.Type: ApplicationFiled: September 27, 2007Publication date: August 7, 2008Inventors: PAUL V. VIITANEN, Carol M. McCutchen, Mark Emptage, Perry G. Caimi, Min Zhang, Yat-Chen Chou
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Publication number: 20080081358Abstract: Xylose-utilizing Z. mobilis strains were found to have improved ethanol production when grown in medium containing mixed sugars including xylose if sorbitol or mannitol was included in the medium. The effect was seen in concentrations of mixed sugars where no growth lag period occurs, as well as in higher sugars concentrations.Type: ApplicationFiled: September 27, 2007Publication date: April 3, 2008Inventors: PAUL VIITANEN, Carol Mc Cutchen, Xu Li, Mark Emptage, Perry Caimi, Min Zhang, Yat-Chen Chou, Mary Franden
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Publication number: 20060148053Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).Type: ApplicationFiled: January 16, 2006Publication date: July 6, 2006Inventors: Mark Emptage, Sharon Haynie, Lisa Laffend, Jeff Pucci, Gregory Whited
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Patent number: 7067300Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).Type: GrantFiled: October 21, 2002Date of Patent: June 27, 2006Assignee: E. I. du Pont de Nemours and CompanyInventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Marshall Whited
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Publication number: 20060121588Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).Type: ApplicationFiled: February 13, 2006Publication date: June 8, 2006Inventors: Mark Emptage, Sharon Haynie, Lisa Laffend, Jeff Pucci, Gregory Whited
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Publication number: 20030157674Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).Type: ApplicationFiled: October 21, 2002Publication date: August 21, 2003Inventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Marshall Whited
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Patent number: 6514733Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).Type: GrantFiled: August 18, 2000Date of Patent: February 4, 2003Assignee: E. I. du Pont de Nemours and CompanyInventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Whited