Patents by Inventor Mark Emptage

Mark Emptage has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190169585
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Application
    Filed: February 14, 2019
    Publication date: June 6, 2019
    Inventors: Benjamin Bower, Mark Emptage, William D. Hitz, Megan Yee Hsi, Thijs Kaper, Bradley R. Kelemen, Steven Kim, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Keith Dumont Wing
  • Patent number: 10273465
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: April 30, 2019
    Assignee: DANISCO US INC.
    Inventors: Benjamin Bower, Megan Yee Hsi, Thijs Kaper, Bradley R. Kelemen, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Steven Kim, William D. Hitz, Mark Emptage, Keith Dumont Wing
  • Publication number: 20160177279
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Application
    Filed: July 27, 2015
    Publication date: June 23, 2016
    Applicant: DANISCO US INC.
    Inventors: Benjamin BOWER, Megan Yee HSI, Thijs KAPER, Bradley R. KELEMEN, Suzanne E. LANTZ, Edmund A. LARENAS, Colin MITCHINSON, Steven KIM, William D. HITZ, Mark EMPTAGE, Keith Dumont WING
  • Publication number: 20130177947
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Application
    Filed: September 22, 2010
    Publication date: July 11, 2013
    Applicant: DANISCO US INC.
    Inventors: Benjamin Bower, Megan Yee Hsi, Thijs Kaper, Bradley R. Keleman, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Steven Kim, William D. Hitz, Mark Emptage, Keith Dumont Wing
  • Patent number: 8465961
    Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: June 18, 2013
    Assignees: E I du Pont de Nemours and Company
    Inventors: Perry G Caimi, Mark Emptage, Xu Li, Paul V Viitanen, Yat-Chen Chou, Mary Ann Franden, Min Zhang
  • Publication number: 20120276607
    Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.
    Type: Application
    Filed: July 3, 2012
    Publication date: November 1, 2012
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY & ALLIANCE FOR SUSTAINABLE ENERGY LLC
    Inventors: PERRY G. CAIMI, MARK EMPTAGE, XU LI, PAUL V. VIITANEN, YAT-CHEN CHOU, MARY ANN FRANDEN, MIN ZHANG
  • Patent number: 8247208
    Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: August 21, 2012
    Assignees: E I du Pont de Nemours and Company
    Inventors: Perry G. Caimi, Mark Emptage, Xu Li, Paul V. Viitanen, Yat-Chen Chou, Mary Ann Franden, Min Zhang
  • Publication number: 20110014670
    Abstract: Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.
    Type: Application
    Filed: December 18, 2009
    Publication date: January 20, 2011
    Applicant: E.I. DU PONT DE NEMOURS AND COMPANY & ALLIANCE FOR SUSTAINABLE ENERGY LLC
    Inventors: PERRY G. CAIMI, Mark Emptage, Xu Li, Paul V. Viitanen, Yat-Chen Chou, Mary Ann Franden, Min Zhang
  • Patent number: 7741084
    Abstract: Production of ethanol using a strain of xylose-utilizing Zymomonas with a genetic modification of the glucose-fructose oxidoreductase gene was found to be improved due to greatly reduced production of xylitol, a detrimental by-product of xylose metabolism synthesized during fermentation.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: June 22, 2010
    Assignees: E. I. du Pont de Nemours and Company, Alliance for Sustainable Energy LLC
    Inventors: Paul V. Viitanen, Carol M. McCutchen, Mark Emptage, Perry G. Caimi, Min Zhang, Yat-Chen Chou
  • Patent number: 7629156
    Abstract: Xylose-utilizing Z. mobilis strains were found to have improved ethanol production when grown in medium containing mixed sugars including xylose if sorbitol or mannitol was included in the medium. The effect was seen in concentrations of mixed sugars where no growth lag period occurs, as well as in higher sugars concentrations.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: December 8, 2009
    Assignees: E.I. du Pont de Nemours and Company, Alliance For Sustainable Energy, LLC
    Inventors: Paul V. Viitanen, Carol M. Mc Cutchen, Xu Li, Mark Emptage, Perry G. Caimi, Min Zhang, Yat-Chen Chou, Mary Ann Franden
  • Publication number: 20090253192
    Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).
    Type: Application
    Filed: February 16, 2009
    Publication date: October 8, 2009
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend
  • Patent number: 7504250
    Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).
    Type: Grant
    Filed: January 16, 2006
    Date of Patent: March 17, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Whited
  • Patent number: 7452710
    Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: November 18, 2008
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Whited
  • Publication number: 20080187973
    Abstract: Production of ethanol using a strain of xylose-utilizing Zymomonas with a genetic modification of the glucose-fructose oxidoreductase gene was found to be improved due to greatly reduced production of xylitol, a detrimental by-product of xylose metabolism synthesized during fermentation.
    Type: Application
    Filed: September 27, 2007
    Publication date: August 7, 2008
    Inventors: PAUL V. VIITANEN, Carol M. McCutchen, Mark Emptage, Perry G. Caimi, Min Zhang, Yat-Chen Chou
  • Publication number: 20080081358
    Abstract: Xylose-utilizing Z. mobilis strains were found to have improved ethanol production when grown in medium containing mixed sugars including xylose if sorbitol or mannitol was included in the medium. The effect was seen in concentrations of mixed sugars where no growth lag period occurs, as well as in higher sugars concentrations.
    Type: Application
    Filed: September 27, 2007
    Publication date: April 3, 2008
    Inventors: PAUL VIITANEN, Carol Mc Cutchen, Xu Li, Mark Emptage, Perry Caimi, Min Zhang, Yat-Chen Chou, Mary Franden
  • Publication number: 20060148053
    Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).
    Type: Application
    Filed: January 16, 2006
    Publication date: July 6, 2006
    Inventors: Mark Emptage, Sharon Haynie, Lisa Laffend, Jeff Pucci, Gregory Whited
  • Patent number: 7067300
    Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: June 27, 2006
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Marshall Whited
  • Publication number: 20060121588
    Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).
    Type: Application
    Filed: February 13, 2006
    Publication date: June 8, 2006
    Inventors: Mark Emptage, Sharon Haynie, Lisa Laffend, Jeff Pucci, Gregory Whited
  • Publication number: 20030157674
    Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).
    Type: Application
    Filed: October 21, 2002
    Publication date: August 21, 2003
    Inventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Marshall Whited
  • Patent number: 6514733
    Abstract: The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present invention, an improved process for the conversion of glucose to 1,3-propanediol is achieved by the use of an E. coli transformed with the Klebsiella pneumoniae dha regulon genes dhaR, orfY, dhaT, orfX, orfW, dhaB1, dhaB2, dhaB3, and orfZ, all these genes arranged in the same genetic organization as found in wild type Klebsiella pneumoniae. In another aspect of the present invention, an improved process for the production of 1,3-propanediol from glucose using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, and a dehydratase reactivation factor compared to an identical process using a recombinant E. coli containing genes encoding a G3PDH, a G3P phosphatase, a dehydratase, a dehydratase reactivation factor and a 1,3-propanediol oxidoreductase (dhaT).
    Type: Grant
    Filed: August 18, 2000
    Date of Patent: February 4, 2003
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark Emptage, Sharon L. Haynie, Lisa A. Laffend, Jeff P. Pucci, Gregory Whited