Patents by Inventor Mark Exley

Mark Exley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11389771
    Abstract: Asymmetric composite membranes and methods for their preparation are disclosed. The membranes comprise a cross-linked poly(vinyl alcohol) polymer coated on a film of cross-linked sulfonated poly(ether ether ketone) adhered to a sheet of hydrophilicitized microporous polyolefin. The microporous polyolefin is typically microporous poly(ethylene). The membranes have improved selectivity with the regard to the rejection of solutes in reverse osmosis and ultrafiltration applications.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: July 19, 2022
    Assignee: HYDROXSYS HOLDINGS LIMITED
    Inventors: Lenka Benacek Craft, Mark Exley, Ashveen Vikash Nand, Dylan Townshend Gifford
  • Patent number: 11291215
    Abstract: Durable asymmetric composite membranes consisting essentially of a film of cross-linked sulfonated poly(ether ether ketone) adhered to a sheet of hydrophilicitized microporous poly(ethylene) are disclosed. The membranes have application in the recovery of water from feed streams where the ability to clean in situ is desirable, for example in dairy processing. Methods of preparing cross-linked sulfonated poly(ether ether ketone) suitable for use as the rejection layer and hydrophilicitized sheets of microporous poly(ethylene) suitable for use as the support layer of such membranes are also disclosed.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: April 5, 2022
    Assignee: HYDROXSYS HOLDINGS LIMITED
    Inventors: Daryl Joseph Briggs, Lenka Benacek Craft, Ashveen Vikash Nand, Mark Exley
  • Patent number: 10335742
    Abstract: Durable asymmetric composite membranes consisting of a film of cross-linked poly(ether ether ketone) adhered to a sheet of hydrophilic microporous poly(ethylene) are disclosed. The membranes are suitable for use in the recovery or removal of water from feed streams where repeated clean-in-place protocols are required such as in the processing of dairy products.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: July 2, 2019
    Assignee: HYDROXSYS HOLDINGS LIMITED
    Inventor: Mark Exley
  • Publication number: 20180015424
    Abstract: Durable asymmetric composite membranes consisting of a film of cross-linked poly(ether ether ketone) adhered to a sheet of hydrophilic microporous poly(ethylene) are disclosed. The membranes are suitable for use in the recovery or removal of water from feed streams where repeated clean-in-place protocols are required such as in the processing of dairy products.
    Type: Application
    Filed: December 28, 2015
    Publication date: January 18, 2018
    Inventor: Mark Exley
  • Patent number: 7856454
    Abstract: A data model that allows for relationships between entities, also referred to as parties, to be modeled as attributes of an entity and for customization of the data model in a manner that facilitates upgrading of the data model. The data model defines a party class that includes a party identifier and a list of relationships of that party with other parties. The relationships may include represented-by relationships, customer-of relationships, contact-of relationships, or employee-of relationships. The party class can be sub-classed (i.e., be a base class for a derived class) depending on the type of party that is being model.
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: December 21, 2010
    Assignee: Siebel Systems, Inc.
    Inventors: Maria Theresa Barnes Leon, Richard Mark Exley, Adam Sherman Christensen, Caroline Muralitharan, Lin Foong Lee, Silvia Eva Tittel, Nardo B. Catahan, Jr.
  • Patent number: 7716675
    Abstract: A method and system for providing an integration environment in which integration processes can be developed independent of integration servers and applications. The integration environment provides an application service interface for each application that is independent of the integration servers. An integration process that is developed to use the application service interface is compatible with any integration server that supports the applications that the integration process accesses. The integration environment provides a common service interface for each type of application. The common service interface is independent of the application that is providing the service and is also independent of the integration server. Thus, an integration process developed to use the common service interface is compatible with any application of the appropriate type and any integration server.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: May 11, 2010
    Assignee: Siebel Systems, Inc.
    Inventors: Richard Mark Exley, Chaochin Wang
  • Patent number: 7711680
    Abstract: Enterprise management information in a first format for use by a first computerized system is transformed into an intermediate format to readily make the stored enterprise management information available for use in a second computerized system that utilizes a second format. The transformation includes a plurality of common data type elements that are adapted to be shared across a plurality of data objects in the intermediate format.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: May 4, 2010
    Assignee: Siebel Systems, Inc.
    Inventors: Maria Theresa Barnes-Leon, Nardo B. Catahan, Jr., Richard Mark Exley
  • Patent number: 7694314
    Abstract: A method and system for providing an integration environment in which integration processes can be developed independent of integration servers and applications. The integration environment provides an application service interface for each application that is independent of the integration servers. An integration process that is developed to use the application service interface is compatible with any integration server that supports the applications that the integration process accesses. The integration environment provides a common service interface for each type of application. The common service interface is independent of the application that is providing the service and is also independent of the integration server. Thus, an integration process developed to use the common service interface is compatible with any application of the appropriate type and any integration server.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: April 6, 2010
    Assignee: Siebel Systems, Inc.
    Inventors: Richard Mark Exley, Maria Theresa Barnes Leon, Hitesh Dholakia, Manoj Kumar Das
  • Patent number: 7287041
    Abstract: Enterprise management information in a first format for use by a first computerized system is transformed into an intermediate format to readily make the stored enterprise management information available for use in a second computerized system that utilizes a second format. The intermediate format includes a plurality of custom data type elements that are adapted for capturing unique customer information that are relevant to the customer's business systems.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: October 23, 2007
    Assignee: Siebel Systems, Inc.
    Inventors: Maria Theresa Barnes-Leon, Nardo B. Catahan, Jr., Richard Mark Exley
  • Publication number: 20070160600
    Abstract: The invention provides compounds and methods for the ex vivo or in vivo expansion of NK T cells, CD1d-reactive T cells, and J?Q+ T cells, and the modulation of their activities. These compounds and methods have diagnostic and therapeutic applications.
    Type: Application
    Filed: October 2, 2006
    Publication date: July 12, 2007
    Applicants: Beth Israel Deaconess Medical Center, Dana-Farber Cancer Institute
    Inventors: Mark Exley, Samuel Wilson, Steven Balk
  • Publication number: 20060286095
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 21, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcolm Gefter
  • Publication number: 20060286097
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 21, 2006
    Inventors: Philiip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcolm Gefter
  • Publication number: 20060286098
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 21, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcolm Gefter
  • Publication number: 20060286094
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 21, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcoml Gefter
  • Publication number: 20060286096
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 21, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Malcolm Gefter, Stephen Powers
  • Publication number: 20060286099
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 21, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcolm Gefter
  • Publication number: 20060280735
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 14, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcolm Gefter
  • Publication number: 20060280736
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 14, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcolm Gefter
  • Publication number: 20060239997
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: June 19, 2006
    Publication date: October 26, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcolm Gefter
  • Publication number: 20060058220
    Abstract: Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are, disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.
    Type: Application
    Filed: February 23, 2005
    Publication date: March 16, 2006
    Inventors: Philip Swain, Victoria Schad, Julia Greenstein, Mark Exley, Barbara Fox, Stephen Powers, Malcolm Gefter