Patents by Inventor Mark F. Maurer
Mark F. Maurer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240002466Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: March 10, 2023Publication date: January 4, 2024Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Dan Ardourel, Daniel William Demonte, Joseph L. Kuijper
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Patent number: 11834490Abstract: Provided herein are immunomodulatory proteins comprising variant CD112 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: July 27, 2017Date of Patent: December 5, 2023Assignee: ALPINE IMMUNE SCIENCES, INC.Inventors: Ryan Swanson, Michael Kornacker, Daniel William Demonte, Mark F. Maurer, Dan Ardourel, Joseph L. Kuijper
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Publication number: 20230381229Abstract: Provided herein are immunomodulatory proteins comprising variant CD155 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: October 14, 2022Publication date: November 30, 2023Applicant: ALPINE IMMUNE SCIENCES, INC.Inventors: Ryan SWANSON, Michael KORNACKER, Daniel William DEMONTE, Mark F. MAURER
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Patent number: 11732022Abstract: Provided herein are immunomodulatory proteins comprising variant PD-L2 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: March 13, 2018Date of Patent: August 22, 2023Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Dan Ardourel, Daniel William Demonte, Joseph L. Kuijper
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Publication number: 20230220039Abstract: Provided herein are immunomodulatory proteins comprising variant PD-L1 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: March 13, 2018Publication date: July 13, 2023Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUJIPER
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Patent number: 11639375Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: March 13, 2018Date of Patent: May 2, 2023Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Joseph L. Kuijper
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Patent number: 11471488Abstract: Provided herein are immunomodulatory proteins comprising variant CD155 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: July 27, 2017Date of Patent: October 18, 2022Assignee: ALPINE IMMUNE SCIENCES, INC.Inventors: Ryan Swanson, Michael Kornacker, Daniel William Demonte, Mark F. Maurer
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Publication number: 20220177587Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: September 19, 2019Publication date: June 9, 2022Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Mark F. MAURER, Stanford L. PENG, Jing YANG, Kristine M. SWIDEREK
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Patent number: 11230588Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: January 28, 2021Date of Patent: January 25, 2022Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Joseph L. Kuijper
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Publication number: 20210324072Abstract: The present invention provides antibodies, or antigen binding fragments thereof, that bind to human TIGIT (T cell immunoreceptor with Ig and ITIM domains), as well as uses of these antibodies or fragments in therapeutic applications, such as in the treatment of cancer or chronic viral infection. Such method of treatment include combination therapy with inhibitors of other immunomodulatory receptor interactions, such as the PD-1/PD-L1 interaction. The invention further provides polynucleotides encoding the heavy and/or light chain variable region of the antibodies, expression vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies, cells comprising the vectors, and methods of making the antibodies or fragments by expressing them from the cells.Type: ApplicationFiled: April 12, 2021Publication date: October 21, 2021Inventors: Mark F. Maurer, Tseng-hui Timothy CHEN, Brigitte DEVAUX, Mohan SRINIVASAN, Susan H. JULIEN, Paul O. SHEPPARD, Daniel F. ARDOUREL, Indrani CHAKRABORTY
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Patent number: 11117950Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: January 29, 2021Date of Patent: September 14, 2021Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Joseph L. Kuijper
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Patent number: 11117948Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: January 28, 2021Date of Patent: September 14, 2021Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Joseph L. Kuijper
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Patent number: 11117949Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: January 29, 2021Date of Patent: September 14, 2021Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Joseph L. Kuijper
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Patent number: 11096988Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: GrantFiled: January 28, 2021Date of Patent: August 24, 2021Assignee: Alpine Immune Sciences, Inc.Inventors: Ryan Swanson, Michael Kornacker, Mark F. Maurer, Joseph L. Kuijper
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Publication number: 20210253668Abstract: Provided herein are immunomodulatory proteins comprising variant CD112 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: July 27, 2017Publication date: August 19, 2021Applicant: ALPINE IMMUNE SCIENCES, INC.Inventors: Ryan SWANSON, Michael KORNACKER, Daniel William DEMONTE, Mark F. MAURER, Dan ARDOUREL, Joseph L. KUIJPER
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Publication number: 20210188942Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 29, 2021Publication date: June 24, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210171603Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 29, 2021Publication date: June 10, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210163571Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 28, 2021Publication date: June 3, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210155669Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 28, 2021Publication date: May 27, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER
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Publication number: 20210155668Abstract: Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.Type: ApplicationFiled: January 28, 2021Publication date: May 27, 2021Applicant: Alpine Immune Sciences, Inc.Inventors: Ryan SWANSON, Michael KORNACKER, Mark F. MAURER, Dan ARDOUREL, Daniel William DEMONTE, Joseph L. KUIJPER