Patents by Inventor Mark Fife

Mark Fife has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Avian Cells for Improved Virus Production
    Publication number: 20190203170
    Abstract: The present Invention provides as avian cell in which the expression or activity of one or more of the following genes, or a homologue thereof: Chicken IFITM1 (SEQ ID No. 1); Chicken IFITM2 (SEQ ID No. 2) and Chicken IFITM3 (SEQ ID No. 3) is reduced. The invention also provides methods for passaging viruses in avian cells, embryos and/or avian cell lines which have reduced expression of one or more IFITM genes and methods which involve investigating the sequence of one or more of the following genes, or a homologue thereof: Chicken IFITM1 (SEQ ID No. 1); Chicken IFITM2 (SEQ ID No. 2) and Chicken IFITM3 (SEQ ID No. 3).
    Type: Application
    Filed: December 21, 2018
    Publication date: July 4, 2019
    Inventors: Mark Fife, Mark Gibson
  • Chicken cells for improved virus production
    Patent number: 10202578
    Abstract: The present Invention provides as avian cell in which the expression or activity of one or more of the following genes, or a homologue thereof: Chicken IFITM 1 (SEQ ID No. 1); Chicken IFITM2 (SEQ ID No. 2) and Chicken IFITM3 (SEQ ID No. 3) is reduced. The invention also provides methods for passaging viruses in avian cells, embryos and/or avian cell lines which have reduced expression of one or more IFITM genes and methods which involve investigating the sequence of one or more of the following genes, or a homologue thereof: Chicken IFITM1 (SEQ ID No. 1); Chicken IFITM2 (SEQ ID No. 2) and Chicken IFITM3 (SEQ ID No. 3).
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: February 12, 2019
    Assignee: THE PIRBRIGHT INSTITUTE
    Inventors: Mark Fife, Mark Gibson
  • AVIAN CELLS FOR IMPROVED VIRUS PRODUCTION
    Publication number: 20160108359
    Abstract: The present Invention provides as avian cell in which the expression or activity of one or more of the following genes, or a homologue thereof: Chicken IFITM 1 (SEQ ID No. 1); Chicken IFITM2 (SEQ ID No. 2) and Chicken IFITM3 (SEQ ID No. 3) is reduced. The invention also provides methods for passaging viruses in avian cells, embryos and/or avian cell lines which have reduced expression of one or more IFITM genes and methods which involve investigating the sequence of one or more of the following genes, or a homologue thereof: Chicken IFITM1 (SEQ ID No. 1); Chicken IFITM2 (SEQ ID No. 2) and Chicken IFITM3 (SEQ ID No. 3).
    Type: Application
    Filed: June 3, 2014
    Publication date: April 21, 2016
    Inventors: Mark Fife, Mark Gibson
  • RESISTANCE TO BACTERIAL INFECTION
    Publication number: 20140189898
    Abstract: The present invention provides a method of identifying an animal having a genotype associated with resistance to bacterial infection comprising the steps of: (a) providing a sample from said animal; (b) determining the alleles at one or more markers of the SAL1 locus to identify the genotype of the marker, wherein said SAL1 locus lies between 54.0 MB to 54.8 MB of chicken Chromosome 5 or an equivalent thereof; and (c) determining whether the genotype is a genotype associated with resistance to bacterial infection.
    Type: Application
    Filed: March 6, 2014
    Publication date: July 3, 2014
    Applicant: The Pirbright Institute
    Inventors: Mark Fife, Peter Kaiser, Nigel Salmon
  • RESISTANCE TO BACTERIAL INFECTION
    Publication number: 20120102583
    Abstract: The present invention provides a method of identifying an animal having a genotype associated with resistance to bacterial infection comprising the steps of: (a) providing a sample from said mammal; (b) determining the alleles at one or more markers of the SAL1 locus to identify the genotype of the marker, wherein said SAL1 locus lies between 54.0 MB to 54.8 MB of chicken Chromosome 5 or an equivalent thereof; and (c) determining whether the genotype is a genotype associated with resistance to bacterial infection.
    Type: Application
    Filed: April 28, 2010
    Publication date: April 26, 2012
    Applicant: INSTITUTE FOR ANIMAL HEALTH
    Inventors: Mark Fife, Peter Kaiser, Nigel Salmon