Patents by Inventor Mark G. McDougall

Mark G. McDougall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxy X rhodamine analogs
    Patent number: 10215751
    Abstract: The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: February 26, 2019
    Assignee: Promega Corporation
    Inventors: Thomas A. Kirkland, Mark G. McDougall, Stephen J. Dwight
  • Carboxy X rhodamine analogs
    Patent number: 10139400
    Abstract: The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: November 27, 2018
    Assignee: Promega Corporation
    Inventors: Thomas A. Kirkland, Mark G. McDougall, Stephen J. Dwight
  • pH sensors
    Patent number: 9702824
    Abstract: Provided herein are fluorescent sensor agents, and methods of use and manufacture thereof. In particular, sensor agents are provided that exhibit a detectable change in fluorescence (e.g., fluorescence intensity) upon alteration of the pH of the surrounding environment (e.g., upon moving from one pH environment to another).
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: July 11, 2017
    Assignee: PROMEGA CORPORATION
    Inventors: Mei Cong, Cesear Corona, Mark G. McDougall, Chad Zimprich
  • CARBOXY X RHODAMINE ANALOGS
    Publication number: 20160320372
    Abstract: The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions.
    Type: Application
    Filed: July 7, 2016
    Publication date: November 3, 2016
    Inventors: Thomas A. Kirkland, Mark G. McDougall, Stephen J. Dwight
  • CARBOXY X RHODAMINE ANALOGS
    Publication number: 20150260725
    Abstract: The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions.
    Type: Application
    Filed: May 28, 2015
    Publication date: September 17, 2015
    Inventors: Thomas A. Kirkland, Mark G. McDougall, Stephen J. Dwight
  • Carboxy X rhodamine analogs
    Patent number: 9056885
    Abstract: The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: June 16, 2015
    Assignee: PROMEGA CORPORATION
    Inventors: Thomas A. Kirkland, Mark G. McDougall, Stephen J. Dwight
  • pH SENSORS
    Publication number: 20150044776
    Abstract: Provided herein are fluorescent sensor agents, and methods of use and manufacture thereof. In particular, sensor agents are provided that exhibit a detectable change in fluorescence (e.g., fluorescence intensity) upon alteration of the pH of the surrounding environment (e.g., upon moving from one pH environment to another).
    Type: Application
    Filed: March 8, 2013
    Publication date: February 12, 2015
    Applicant: PROMEGA CORPORATION
    Inventors: Mei Cong, Cesear Corona, Mark G. McDougall, Chad Zimprich
  • O.sup.6 -substituted guanine compositions and methods for depleting O.sup.6
    Patent number: 5691307
    Abstract: Novel O.sup.6 -substituted guanine compounds and pharmaceutical compositions thereof are useful for effectively reducing O.sup.6 -alkylguanine-DNA alkyltransferase (AGT). The novel compounds are useful for treating tumors and when used with anti-neoplastic alkylating agents enhance the chemotherapeutic treatment of tumor cells in a host.
    Type: Grant
    Filed: June 7, 1994
    Date of Patent: November 25, 1997
    Assignees: The United States of America as represented by the Department of Health and Human Services, The Penn State Research Foundation, Arch Development Corporation
    Inventors: Robert C. Moschel, M. Eileen Dolan, Anthony E. Pegg, Mark G. McDougall, Mi-Young Chae