Abstract: A system and method for dosing SO2 into wine barrels is achieved with a device including a compressed gas cylinder containing compressed liquefied SO2 under its own vapor pressure, a dosing wand fluidly connected to the cylinder via a hose that is adapted and configured to allow a flow of gaseous SO2 from the source to the dosing wand. The dosing wand includes a hollow needle dispensing nozzle and a SO2 batch flow controller in fluid communication between the hose and the hollow needle. The hollow needle dispensing nozzle is adapted and configured to pierce through a bung opening of a wine barrel and has at least one aperture at a terminal end thereof to allow gaseous SO2 to be dispensed into an interior of the wine barrel.

Abstract: An aircraft component including a first section adapted to be attached at an exterior surface of an aircraft to close an access opening through the exterior surface; and a second section extending outward from the first section and forming heat transfer surfaces to transfer heat from the first section to air passing by the exterior surface and second section during flight of the aircraft. The first and second sections are integrally formed as a one-piece member.

Abstract: The present invention provides cytochrome 2C9 proteins which have been modified to introduce a proline residue at positions 220 or 222 of the wild type sequence which can be crystallised to provide high resolution structures. The structures may be used for homology modelling of other cytochrome P450 structures such as 2C8, 2C18 and 2C19, and for analysis of the interaction of ligands with P450.