Abstract: Described herein are fatty acid-bifunctional degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment of conditions, diseases, and disorders mediated by various target proteins.

Abstract: Methods and systems for generating a model to be used for evaluating credit and loan applications are provided. The method includes: training a first model by using all features included in a universe of candidate features; measuring a first metric that relates to an accuracy of the first model and a second metric that relates to a disparity of the first model; constructing a graph based on pairwise correlations of the features; clustering the features into feature sets; estimating a respective disparity contribution associated with each feature set; selecting feature sets to be included in a second model; training, the second model; measuring the first metric and the second metric with respect to the second model; and determining whether the second model satisfies a predetermined accuracy level and a predetermined disparity reduction with respect to the first model.

Abstract: A method for performing sequential multi-model race estimation is provided. The method includes acquiring a dataset of identification information of individuals; executing a first model within a multi-model system for estimating a race for each of the individuals included in the dataset; subsequent to executing the first model, executing a second model within the multi-model system for estimating a race for individuals included in the dataset that were unable to be estimated via the first model; and subsequent to executing the second model, executing a third model within the multi-model system for estimating a race for individuals included in the dataset that were unable to be estimated via the first model and the second model, in which the third model estimates a race for individuals with insufficient data fields.

Abstract: Some examples provide a fire-rated elevator door frame assembly with a flush transom. The transom includes a transom assembly. A fire-rated partition sits behind the transom on the hoistway side of the elevator doors. Architectural cladding can be applied to the front of the transom and to the front of the elevator doors giving the appearance that the flush transom extends high above the elevator doors.

Abstract: An apparatus for first value device verification, the apparatus comprising at least a processor and a memory communicatively connected to the at least a processor. The memory contains instructions configuring the at least a processor to receive a first value request from a user on a user device, acquire a device identifier of the user device as a function of the first value request, obtain a device authentication code corresponding to the device identifier, confirm that the user owns the user device as a function of the device authentication code, and calculate a first value once the user device is confirmed to belong to the user.

Abstract: A fire-rated sliding elevator glass door is provided. The door includes a face panel, a liner, a fire-rated glass panel, and a retainer that retains the glass panel in the door frame. The elevator door is configured to pass a 90-minute fire rating test. The elevator door can be implemented as a single-speed side open elevator door, a single-speed center open elevator door, a two-speed side opening sliding elevator door, or a two-speed center opening sliding elevator door. A method of constructing the fire-rated elevator door is provided.

Abstract: A fire-rated sliding elevator glass door is provided. The door includes a face panel, a liner, a fire-rated glass panel, and a retainer that retains the glass panel in the door frame. The elevator door is configured to pass a 90-minute fire rating test. The elevator door can be implemented as a single-speed side open elevator door, a single-speed center open elevator door, a two-speed side opening sliding elevator door, or a two-speed center opening sliding elevator door. A method of constructing the fire-rated elevator door is provided.

Abstract: Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula I

Abstract: The present application is directed to a spray booth comprising a first enclosure for applying spray material and a second enclosure for drying spray material. An exhaust system is in fluid connection with the first and second enclosures. A fire suppression system is in fluid connection with at least one component chosen from the first enclosure, the second enclosure and the exhaust system. A processor is in data communication with at least one component chosen from the spray enclosure, the drying enclosure, the exhaust system and the fire suppression system.

Abstract: A method and apparatus is provided to simplify sandblasting processes while increasing applied coverage areas in sandblasting operations. The method and apparatus provide a manifold assembly having a plurality of nozzles and that is rigidly attached to an air supply. The manifold is supplied with abrasive material via a plurality of angularly attached sand supply hoses which are coupled to an abrasive material supply. The manifold assembly is pressurized with the supply of air. An article is sandblasted by drawing sand through the hoses and out of the plurality of nozzles using the pressurized air through the manifold assembly.

Abstract: There is provided an ultrasonic welding apparatus that includes a magnetic source and a ferromagnetic device to apply pressure to at least one component being joined during the ultrasonic welding process. The magnetic source is positioned proximate the ultrasonic transducer, and when the component to be ultrasonically welded is adjacent the ultrasonic transducer, the ferromagnetic device is positioned opposite the component from the magnetic source and the ultrasonic transducer to apply pressure. A magnetic source comprising an electromagnet provides an adjustable pressure to the component. The ferromagnetic device defines a generally spherical surface so that it advantageously remains in position relative to the magnetic source if the component is moved relative to the ferromagnetic device. In addition, the ferromagnetic device may comprise a magnet to increase the magnetic force between the magnetic source and ferromagnetic device, which increases the pressure applied to the component.

Abstract: A method and apparatus is provided to simplify sandblasting processes while increasing applied coverage areas in sandblasting operations. The method and apparatus provide a manifold assembly having a plurality of nozzles and that is rigidly attached to an air supply. The manifold is supplied with abrasive material via a plurality of angularly attached sand supply hoses which are coupled to an abrasive material supply. The manifold assembly is pressurized with the supply of air. An article is sandblasted by drawing sand through the hoses and out of the plurality of nozzles using the pressurized air through the manifold assembly.