Patents by Inventor Mark Gandelman
Mark Gandelman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10899687Abstract: The present invention provides a halo-de-carboxylation process for the preparation of organic chlorides, organic bromides and mixtures thereof, from their corresponding carboxylic acids, using a chlorinating agent selected from trichloroisocyanuric acid (TCCA), dichloroisocyanuric acid (DCCA), or combination thereof, and a brominating agent.Type: GrantFiled: October 6, 2016Date of Patent: January 26, 2021Assignee: Technion Research & Development Foundation LimitedInventors: Mark Gandelman, Gennady Nisnevich, Kseniya Kulbitski, Alexander Artaryan
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Patent number: 10399917Abstract: The present invention provides a process for the preparation of organic bromides, by a radical bromodecarboxylation of carboxylic acids with a bromoisocyanurate.Type: GrantFiled: October 6, 2016Date of Patent: September 3, 2019Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Mark Gandelman, Gennady Nisnevich, Kseniya Kulbitski, Alexander Artaryan
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Publication number: 20180282247Abstract: The present invention provides a halo-de-carboxylation process for the preparation of organic chlorides, organic bromides and mixtures thereof, from their corresponding carboxylic acids, using a chlorinating agent selected from trichloroisocyanuric acid (TCCA), dichloroisocyanuric acid (DCCA), or combination thereof, and a brominating agent.Type: ApplicationFiled: October 6, 2016Publication date: October 4, 2018Applicant: Technion Research & Development Foundation LimitedInventors: Mark GANDELMAN, Gennady NISNEVICH, Kseniya KULBITSKI, Alexander ARTARYAN
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Publication number: 20180273450Abstract: The present invention provides a process for the preparation of organic bromides, by a radical bromodecarboxylation of carboxylic acids with a bromoisocyanurate.Type: ApplicationFiled: October 6, 2016Publication date: September 27, 2018Applicant: Technion Research & Development Foundation LimitedInventors: Mark GANDELMAN, Gennady NISNEVICH, Kseniya KULBITSKI, Alexander ARTARYAN
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Patent number: 9637462Abstract: The present invention provides new stable crystalline N-iodoamides-1-iodo-3,5,5-trimethylhydantoin (1-ITMH) and 3-iodo-4,4-dimethyl-2-oxazolidinone (IDMO). The present invention further provides a process for the preparation of organic iodides using N-iodoamides of this invention and recovery of the amide co-products from waste water.Type: GrantFiled: November 5, 2014Date of Patent: May 2, 2017Assignee: Technion Research & Development Foundation LimitedInventors: Gennady Nisnevich, Kseniya Kulbitski, Mark Gandelman, Alexander Artaryan
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Publication number: 20160272598Abstract: The present invention provides new stable crystalline N-iodoamides -1-iodo-3,5,5-trimethylhydantoin (1-ITMH) and 3-iodo-4,4-dimethyl-2-oxazolidinone (IDMO). The present invention further provides a process for the preparation of organic iodides using N-iodoamides of this invention and recovery of the amide co-products from waste water.Type: ApplicationFiled: November 5, 2014Publication date: September 22, 2016Inventors: Gennady NISNEVICH, Kseniya KULBITSKI, Mark GANDELMAN
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Patent number: 8822516Abstract: This invention is directed to a process for the preparation of high yield alkyl or aryl iodide from its corresponding carboxylic acid using N-iodo amides.Type: GrantFiled: June 9, 2011Date of Patent: September 2, 2014Assignee: Technion Research & Development Foundation LimitedInventors: Gennady Nisnevich, Mark Gandelman, Kseniya Kulbitski
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Patent number: 8481746Abstract: A novel process of preparing tridentate ligands containing a diarylphosphine electron donating group are disclosed. Use of this process for preparing a combinatorial library of such tridentate ligands and of organometallic complexes containing same is also disclosed. Further disclosed are novel diarylphosphine-containing compounds that can serve as tridentate ligands (e.g., pincer ligands), combinatorial libraries of such tridentate ligands, organometallic complexes containing these ligands (e.g., pincer complexes), and combinatorial libraries of such complexes. Methods utilizing these libraries for screening for candidate organometallic catalysts are also disclosed.Type: GrantFiled: May 14, 2009Date of Patent: July 9, 2013Assignee: Technion Research & Development Foundation LimitedInventors: Mark Gandelman, Elaine Melissa Schuster
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Publication number: 20130165658Abstract: This invention is directed to a process for the preparation of high yield alkyl or aryl iodide from its corresponding carboxylic acid using N-iodo amides.Type: ApplicationFiled: June 9, 2011Publication date: June 27, 2013Inventors: Gennady Nisnevich, Mark Gandelman, Kseniya Kulbitski
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Patent number: 8318960Abstract: A novel process of preparing tridentate ligands containing one or more of a diarylphosphine and/or dialkylphosphine electron donating groups are disclosed. Use of this process for preparing a combinatorial library of such tridentate ligands and of organometallic complexes containing same is also disclosed. Further disclosed are novel diarylphosphine-containing and dialkylphosphine-containing compounds that can serve as tridentate ligands (e.g., pincer ligands), combinatorial libraries of such tridentate ligands, organometallic complexes containing these ligands (e.g., pincer complexes), and combinatorial libraries of such complexes. Methods utilizing these libraries for screening for candidate organometallic catalysts are also disclosed. Novel precursor molecules useful for preparing the tridentate ligands and processes of preparing same are also disclosed.Type: GrantFiled: May 13, 2010Date of Patent: November 27, 2012Assignee: Technion Research & Development Foundation Ltd.Inventors: Mark Gandelman, Elaine Melissa Schuster, Gennady Nisnevich
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Publication number: 20100292084Abstract: A novel process of preparing tridentate ligands containing one or more of a diarylphosphine and/or dialkylphosphine electron donating groups are disclosed. Use of this process for preparing a combinatorial library of such tridentate ligands and of organometallic complexes containing same is also disclosed. Further disclosed are novel diarylphosphine-containing and dialkylphosphine-containing compounds that can serve as tridentate ligands (e.g., pincer ligands), combinatorial libraries of such tridentate ligands, organometallic complexes containing these ligands (e.g., pincer complexes), and combinatorial libraries of such complexes. Methods utilizing these libraries for screening for candidate organometallic catalysts are also disclosed. Novel precursor molecules useful for preparing the tridentate ligands and processes of preparing same are also disclosed.Type: ApplicationFiled: May 13, 2010Publication date: November 18, 2010Applicant: Technion Research & Development Foundation Ltd.Inventors: Mark GANDELMAN, Elaine Melissa Schuster, Gennady Nisnevich
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Publication number: 20100292100Abstract: A novel process of preparing tridentate ligands containing a diarylphosphine electron donating group are disclosed. Use of this process for preparing a combinatorial library of such tridentate ligands and of organometallic complexes containing same is also disclosed. Further disclosed are novel diarylphosphine-containing compounds that can serve as tridentate ligands (e.g., pincer ligands), combinatorial libraries of such tridentate ligands, organometallic complexes containing these ligands (e.g., pincer complexes), and combinatorial libraries of such complexes. Methods utilizing these libraries for screening for candidate organometallic catalysts are also disclosed.Type: ApplicationFiled: May 14, 2009Publication date: November 18, 2010Applicant: Technion Research & Development Foundation Ltd.Inventors: Mark GANDELMAN, Elaine Melissa SCHUSTER
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Patent number: 6844442Abstract: The present invention provides a process for preparing a metal carbene complex of formula (I): wherein M is a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium; L denotes neutral donor ligands ligated to said metal, such groups being the same or different; X is an anionic ligand; R1 and R2 are each independently selected from the group consisting of hydrogen, substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted C2-C20 alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted vinyl, a is 2 or 3 and b is 1 or 2, such process comprising reacting a sulfur ylide of the formula Ar2S?CR1R2 or its precursor with an appropriate metal complex comprising a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium, said metal complex being alsoType: GrantFiled: April 15, 2002Date of Patent: January 18, 2005Assignee: Yeda Research and Development Company, Ltd.Inventors: David Milstein, Mark Gandelman, Nissan Ashkenazi, Boris Rybtchinski
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Publication number: 20040176626Abstract: The present invention provides a process for preparing a metal carbene complex of formula (I): wherein M is a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium; L denotes neutral donor ligands ligated to said metal, such groups being the same or different; X is an anionic ligand; R1 and R2 are each independently selected from the group consisting of hydrogen, substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted C2-C20 alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted vinyl, a is 2 or 3 and b is 1 or 2, such process comprising reacting a sulfur ylide of the formula Ar2S═CR1R2 or its precursor with an appropriate metal complex comprising a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium, said metal complex beingType: ApplicationFiled: April 28, 2004Publication date: September 9, 2004Inventors: David Milstein, Mark Gandelman, Nissan Ashkenazi, Boris Rybtchinski