Abstract: A process for the preparation of a shaped MOF, the process comprising: providing a first reactant comprising at least one metal in ionic form and a second reactant comprising at least one organic ligand capable of associating with said metal in ionic form, and optionally a solvent; allowing the first and second reactants to react to form a MOF; and forming a shaped body directly from the mixture of step b) using an extruder or continuous kneader; wherein the initial ratio of the at least one metal in ionic form to the at least one organic ligand is controlled such that shaped bodies having a minimum defined crush strength are formed without the use of an external binder or lubricant.

Abstract: The present invention relates to a process for preparing a magnesium formate based metal-organic framework. The process comprises (a) combining magnesium or magnesium oxide with formic acid; (b) heating the reaction mixture of step (a) at a temperature of between 70° C. and 200° C.; (c) combining formic acid with the reaction mixture of step (b); and (d) heating the reaction mixture of step (c) at a temperature of between 70° C. and 200° C. Steps (c) and (d) may be heated up to 5 times.

Abstract: A process for the preparation of a shaped MOF, the process comprising: providing a first reactant comprising at least one metal in ionic form and a second reactant comprising at least one organic ligand capable of associating with said metal in ionic form, and optionally a solvent; allowing the first and second reactants to react to form a MOF; and forming a shaped body directly from the mixture of step b) using an extruder or continuous kneader; wherein the initial ratio of the at least one metal in ionic form to the at least one organic ligand is controlled such that shaped bodies having a minimum defined crush strength are formed without the use of an external binder or lubricant.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.

Abstract: A process for gathering data from a plurality of users at remote terminals connected to a central database that restricts the data entered into the central database by providing users with predefined responses to scripted prompts and screening the new data entered into the central database for erroneous responses by comparing the data with existing data through a series of rules. In an alternate embodiment, the present invention includes a process for gathering and analyzing information that includes maintaining a central database, accessing the central database from a remote terminal through an interface, entering information into the central database through the interface, validating the entered information against a set of rules and analyzing the validated information to generate performance indicators for the equipment placed into service. The interface preferably restricts the information entering the central database to a controlled group of responses to a series of scripted prompts.

Abstract: A method and apparatus for fabricating a MEMS apparatus having a device layer with an optical surface that is supported by a pedestal on a planar support layer that is suspended for movement with respect to a base support by hinge elements disposed in a different plane from the planar support layer. The surface area of the optical surface is maximized with respect to the base support to optimize the fill factor of the optical surface and afford a high passband. The height of the pedestal is selected to position the device layer sufficiently above the base support to afford an unobstructed predetermined angular rotation about each axis. The hinges may be made of thin-film material, fabricated by way of surface micromachining techniques. The hinges are disposed underneath the device layer enabling the optical surface to be maximized so that the entire surface becomes usable (e.g., for optical beam manipulation).

Abstract: Effects of diffraction of a spectral beam from an edge of the micromirrors are reduced in order to optimize the passband in a wavelength selective switch. The effects of diffraction on the pass band may be reduced by appropriate modification of the edges of the micromirrors, by modification of the input and/or output ports to allow for attenuation by rotation of the micromirror about the switching axis, by using rotation of the micromirror about both the attenuation axis and the switching axis to achieve the desired level of attenuation, by inserting an aperture at a focal plane or external to the device to reduce the magnitude of the micromirror edge diffraction transmitted to any or all output ports, or by appropriate filtering of angular frequencies with a diffraction grating used to separate a multi-channel optical signal into constituent spectral beams.

Abstract: A wavelength selective switch architecture for ROADMs for switching the spectral channels of a multi-channel, multi-wavelength optical signal between input and output ports employs a biaxial MEMS port mirror array for optimal coupling efficiency and ITU grid alignment, an anamorphic beam expander for expanding input optical signals to create an elongated beam profile, a diffraction grating for spatially separating the spectral channels, an anamorphic focusing lens system, an array of biaxial elongated channel MEMS micromirrors, a built-in Optical Channel Monitor, and an electronic feedback control system. The bi-axial channel micromirrors are rotatable about one axis to switch spectral channels between ports, and are rotatable about an orthogonal axis to vary the coupling of the spectral channel to an output port and control attenuation of the spectral signal for complete blocking or for a predetermined power level.