Abstract: An embodiment includes an inertial torque device (ITD) for calibrating a viscometer. The ITD comprises a body, a coupling for connecting the body to a viscometer measurement interface, a rotatable inertial load device coupled to the body, an electric motor coupled to the rotatable inertial load device and coupled to the body, and a controller configured to calibrate the viscometer by controlling the electric motor to rotate the rotatable inertial load device at a predetermined acceleration to apply a predetermined torque to the coupling connected to the viscometer.

Abstract: An embodiment includes an inertial torque device (ITD) for calibrating a viscometer. The ITD comprises a body, a coupling for connecting the body to a viscometer measurement interface, a rotatable inertial load device coupled to the body, an electric motor coupled to the rotatable inertial load device and coupled to the body, and a controller configured to calibrate the viscometer by controlling the electric motor to rotate the rotatable inertial load device at a predetermined acceleration to apply a predetermined torque to the coupling connected to the viscometer.

Abstract: The present invention provides compositions and methods of for improving the Health-Related Quality of Life of a subject suffering from rheumatoid arthritis, comprising administering to the subject an effective amount of sarilumab.

Abstract: The present invention provides compositions and methods of treating and improving the symptoms of rheumatoid arthritis using an antibody that specifically binds human interleukin-6 receptor (hIL-6R).

Abstract: An improved system and method of performing capacitance measurements that provides a fast digital response and a reduced output error. The capacitance measurement system includes a circuit configuration that has a variable capacitor and at least one reference capacitor connected to one another at a common node, which in turn is connected to the input of an analog-to-digital converter. The circuit configuration further includes an array of switches coupled between the variable and reference capacitors and the supply voltage, a reference voltage, and ground, respectively. The switched variable and reference capacitors are employed in conjunction with the A-to-D converter to perform, at the common node, a plurality of direct voltage measurements for use in generating an expression defining the capacitance of the variable capacitor.

Abstract: An improved system and method of performing capacitance measurements that provides a fast digital response and a reduced output error. The capacitance measurement system includes a circuit configuration that has a variable capacitor and at least one reference capacitor connected to one another at a common node, which in turn is connected to the input of an analog-to-digital converter.

Abstract: Compositions and methods are provided for prognostic classification of autoimmune disease patients into subtypes, which subtypes are informative of the patient's need for therapy and responsiveness to a therapy of interest. The patterns of circulating blood levels of serum autoantibodies and/or cytokines provides for a signature pattern that can identify patients likely to benefit from therapeutic intervention as well as discriminate patients that have a high probability of responsiveness to a therapy from those that have a low probability of responsiveness. Additionally, serum autoantibody and/or cytokine signature patterns can be utilized to monitor responses to therapy. Assessment of this signature pattern of autoantibodies and/or cytokines in a patient thus allows improved methods of care. In one embodiment of the invention, the autoimmune disease is rheumatoid arthritis.