Abstract: Processes and devices provide parenteral delivery of therapeutic fluids, in particular high-viscosity therapeutic fluids (e.g., protein therapeutics), by a chemical reaction that generates a gas. A device may include a first actuation chamber containing a first reagent, a second reaction chamber containing a second reagent, and a third therapeutic fluid chamber containing the therapeutic fluid. In a loaded configuration, a plunger separates the first chamber from the second chamber. In a delivery configuration, the plunger allows the first reagent from the first chamber to communicate and react with the second reagent from the second chamber. The generated gas acts upon a plunger to deliver the therapeutic fluid from the third chamber.

Abstract: An automated package Pickup and Receiving Station (PRS) (100) with autonomous ground vehicles (AGV) (18) are presented, which may be used to pick up, deliver and securely store packages (28), parcels, mail, prepared food, groceries or other items that may be placed in a tray, which may include an integrated container. A portal (10) facilitates loading of items into, and removal of items from, the PRS (100). Within the PRS (100), items (28) may be transported from source to destination on standardized trays (25), via a two-dimensional gantry (32) and an end of arm tool (22). The gantry (32) may be oriented for movement through a central corridor (21) in the PRS (100), with end of arm tool (22) adapted for pushing trays towards, or pulling trays from, either side of the gantry (32). Items may be stored on a tray (25) in internal shelving (20), or placed directly into an AGV (18), on either side of the PRS (100).

Abstract: An automated package Pickup and Receiving Station (PRS) (100) with autonomous ground vehicles (AGV) (18) are presented, which may be used to pick up, deliver and securely store packages (28), parcels, mail, prepared food, groceries or other items that may be placed in a tray, which may include an integrated container. A portal (10) facilitates loading of items into, and removal of items from, the PRS (100). Within the PRS (100), items (28) may be transported from source to destination on standardized trays (25), via a two-dimensional gantry (32) and an end of arm tool (22). The gantry (32) may be oriented for movement through a central corridor (21) in the PRS (100), with end of arm tool (22) adapted for pushing trays towards, or pulling trays from, either side of the gantry (32). Items may be stored on a tray (25) in internal shelving (20), or placed directly into an AGV (18), on either side of the PRS (100).

Abstract: A system for parcel delivery may be provided using a package Pickup and Receiving Stations (PRS), sometimes also referred to as a Hub or Local Automated Hub. In some applications, it may be desirable to provide a number of PRSs located in areas having a high volume of local package delivery. Parcels directed to a recipient within an area serviced by the PRS may be delivered in bulk to the PRS by a parcel carrier. The PRS may then attend to final delivery to each parcel's recipient, preferably using an automated ground vehicle (AGV). Additionally or alternatively, consumers may tender packages to an AGV for, e.g., subsequent retrieval by a package carrier for further transport.

Abstract: A wheel end assembly having a steering knuckle, a hub, and a compression ring. The steering knuckle may have an opening that may extend around a spindle. The hub may be rotatably disposed on the spindle. The compression ring may be disposed on the hub and may be at least partially disposed in the opening.

Abstract: A system for parcel delivery may be provided using a package Pickup and Receiving Stations (PRS), sometimes also referred to as a Hub or Local Automated Hub. In some applications, it may be desirable to provide a number of PRSs located in areas having a high volume of local package delivery. Parcels directed to a recipient within an area serviced by the PRS may be delivered in bulk to the PRS by a parcel carrier. The PRS may then attend to final delivery to each parcel's recipient, preferably using an automated ground vehicle (AGV). Additionally or alternatively, consumers may tender packages to an AGV for, e.g., subsequent retrieval by a package carrier for further transport.

Abstract: An automated package Pickup and Receiving Station (PRS) (100) with autonomous ground vehicles (AGV) (18) are presented, which may be used to pick up, deliver and securely store packages (28), parcels, mail, prepared food, groceries or other items that may be placed in a tray, which may include an integrated container. A portal (10) facilitates loading of items into, and removal of items from, the PRS (100). Within the PRS (100), items (28) may be transported from source to destination on standardized trays (25), via a two-dimensional gantry (32) and an end of arm tool (22). The gantry (32) may be oriented for movement through a central corridor (21) in the PRS (100), with end of arm tool (22) adapted for pushing trays towards, or pulling trays from, either side of the gantry (32). Items may be stored on a tray (25) in internal shelving (20), or placed directly into an AGV (18), on either side of the PRS (100).

Abstract: A wheel end assembly having a steering knuckle, a hub, and a compression ring. The steering knuckle may have an opening that may extend around a spindle. The hub may be rotatably disposed on the spindle. The compression ring may be disposed on the hub and may be at least partially disposed in the opening.

Abstract: A method of capturing a screen includes monitoring screen changes on a first display system and inserting information into a queue, the information including a first type of information and a second type of information, reading the information from the queue and maintaining a dirty region describing areas of the screen which have been changed, wherein areas affected by the first type of information are added to the dirty region and areas affected by the second type of information are subtracted from the dirty region.

Abstract: In order to synchronise video and audio signals, a video test signal and an audio test signal are generated at the transmitting end of a transmission link, and transmitted over the link. The video test signal has first and second active picture periods of contrasting states. The audio test signal has first and second periods of contrasting states. As generated, the video and audio test signals have a predetermined timing relationship—for example, their changes of respective states may be coincident in time. At the receiving end of the link, the video and audio test signals as received are detected, and any difference of timing between the video and audio test signals is derived from their changes of respective states, measured and displayed, including an indication of whether the video signal arrived before the audio signal or vice-versa.

Abstract: A method of capturing a screen includes monitoring screen changes on a first display system and inserting information into a queue, the information including a first type of information and a second type of information, reading the information from the queue and maintaining a dirty region describing areas of the screen which have been changed, wherein areas affected by the first type of information are added to the dirty region and areas affected by the second type of information are subtracted from the dirty region.