Patents by Inventor Mark Gomelsky

Mark Gomelsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240390249
    Abstract: Materials and methods are provided for preventing and dispersing biofilms. Methods and compositions are described for preventing and treating dental caries. Materials and methods are provided for producing antibiofilm agents from natural products, including maple (Acer sp.). Compositions are provided for inhibiting Sortase A activity in Bacillota.
    Type: Application
    Filed: July 30, 2024
    Publication date: November 28, 2024
    Applicant: University of Wyoming
    Inventors: Mark Gomelsky, Ahmed Elbakush, Alex M. Fulano
  • Patent number: 12048309
    Abstract: Methods and compositions for inhibiting or dispersing biofilms produced by Listeria monocytogenes on plant matter are described. Embodiments include using formulations comprising active chemical constituents and aqueous extracts or sap from certain trees. Methods of using and producing aqueous formulations derived from hickory and maple wood are provided. Formulations and methods are provided for preventing and dispersing exopolysaccharide-rich listerial biofilms.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: July 30, 2024
    Assignee: University of Wyoming
    Inventors: Mark Gomelsky, Ahmed Elbakush
  • Publication number: 20230049275
    Abstract: Methods and compositions for inhibiting or dispersing biofilms produced by Listeria monocytogenes on plant matter are described. Embodiments include using formulations comprising active chemical constituents and aqueous extracts or sap from certain trees. Methods of using and producing aqueous formulations derived from hickory and maple wood are provided. Formulations and methods are provided for preventing and dispersing exopolysaccharide-rich listerial biofilms.
    Type: Application
    Filed: August 1, 2022
    Publication date: February 16, 2023
    Applicant: University of Wyoming
    Inventors: Mark Gomelsky, Ahmed Elbakush
  • Patent number: 11525117
    Abstract: The present disclosure relates to microbial stem cell technology that enables a growing microbial culture to stably maintain two or more distinct cell types in a ratio that can be genetically programmed and/or dynamically controlled during cultivation. It is contemplated that embodiments described herein can be utilized to increase product yield in microbial fermentations and advanced engineering of biomaterials using genetically engineered microbial cells, among others.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: December 13, 2022
    Assignee: University of Wyoming
    Inventors: Grant Bowman, Nikolai Mushnikov, Mark Gomelsky
  • Patent number: 11291209
    Abstract: Compositions and uses involving L. monocytogenes PssZ, as well as homologs, variants, and fragments thereof, are described.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: April 5, 2022
    Assignee: University of Wyoming
    Inventors: Mark Gomelsky, Kurt Miller, Volkan Köseo{hacek over (g)}lu
  • Publication number: 20190387746
    Abstract: Compositions and uses involving L. monocytogenes PssZ, as well as homologs, variants, and fragments thereof, are described.
    Type: Application
    Filed: August 15, 2019
    Publication date: December 26, 2019
    Applicant: University of Wyoming
    Inventors: Mark Gomelsky, Kurt Miller, Volkan Köseoglu
  • Patent number: 10383338
    Abstract: Compositions and uses involving L. monocytogenes PssZ, as well as homologs, variants, and fragments thereof, are described.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: August 20, 2019
    Assignee: University of Wyoming
    Inventors: Mark Gomelsky, Kurt Miller, Volkan Köseo{hacek over (g)}lu
  • Patent number: 10041057
    Abstract: Methods and constructs are provided for controlling processes in live animals, plants or microbes via genetically engineered near-infrared light-activated or light-inactivated proteins including chimeras including the photosensory modules of bacteriohytochromes and output modules that possess enzymatic activity and/or ability to bind to DNA, RNA, protein, or small molecules. DNA encoding these proteins are introduced as genes into live animals, plants or microbes, where their activities can be turned on by near-infrared light, controlled by the intensity of light, and turned off by near-infrared light of a different wavelength than the activating light. These proteins can regulate diverse cellular processes with high spatial and temporal precision, in a nontoxic manner, often using external light sources.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: August 7, 2018
    Assignee: University of Wyoming
    Inventors: Mark Gomelsky, Min-Hyung Ryu
  • Publication number: 20170332643
    Abstract: Compositions and uses involving L. monocytogenes PssZ, as well as homologs, variants, and fragments thereof, are described.
    Type: Application
    Filed: October 29, 2015
    Publication date: November 23, 2017
    Applicant: University of Wyoming
    Inventors: Mark Gomelsky, Kurt Miller, Volkan Köseo?lu
  • Publication number: 20170081652
    Abstract: Methods and constructs are provided for controlling processes in live animals, plants or microbes via genetically engineered near-infrared light-activated or light-inactivated proteins including chimeras including the photosensory modules of bacteriohytochromes and output modules that possess enzymatic activity and/or ability to bind to DNA, RNA, protein, or small molecules. DNA encoding these proteins are introduced as genes into live animals, plants or microbes, where their activities can be turned on by near-infrared light, controlled by the intensity of light, and turned off by near-infrared light of a different wavelength than the activating light. These proteins can regulate diverse cellular processes with high spatial and temporal precision, in a nontoxic manner, often using external light sources.
    Type: Application
    Filed: January 19, 2016
    Publication date: March 23, 2017
    Inventors: Mark Gomelsky, Min-Hyung Ryu
  • Publication number: 20150013024
    Abstract: Methods and constructs are provided for controlling processes in live animals, plants or microbes via genetically engineered near-infrared light-activated or light-inactivated proteins including chimeras including the photosensory modules of bacteriohytochromes and output modules that possess enzymatic activity and/or ability to bind to DNA, RNA, protein, or small molecules. DNA encoding these proteins are introduced as genes into live animals, plants or microbes, where their activities can be turned on by near-infrared light, controlled by the intensity of light, and turned off by near-infrared light of a different wavelength than the activating light. These proteins can regulate diverse cellular processes with high spatial and temporal precision, in a nontoxic manner, often using external light sources.
    Type: Application
    Filed: July 9, 2014
    Publication date: January 8, 2015
    Applicant: UNIVERSITY OF WYOMING
    Inventors: Mark Gomelsky, Min-Hyung Ryu
  • Patent number: 8835399
    Abstract: Methods and constructs are provided for controlling processes in live animals, plants or microbes via genetically engineered near-infrared light-activated or light-inactivated proteins including chimeras including the photosensory modules of bacteriophytochromes and output modules that possess enzymatic activity and/or ability to bind to DMA, RNA, protein, or small molecules. DNA encoding these proteins are introduced as genes into live animals, plants or microbes, where their activities can be turned on by near-infrared light, controlled by the intensity of light, and turned off by near-infrared light of a different wavelength than the activating light. These proteins can regulate diverse cellular processes with high spatial and temporal precision, in a nontoxic manner, often using external light sources.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: September 16, 2014
    Assignee: University of Wyoming
    Inventors: Mark Gomelsky, Min-Hyung Ryu
  • Publication number: 20130030041
    Abstract: Methods and constructs are provided for controlling processes in live animals, plants or microbes via genetically engineered near-infrared light-activated or light-inactivated proteins including chimeras including the photosensory modules of bacteriohytochromes and output modules that possess enzymatic activity and/or ability to bind to DMA, RNA, protein, or small molecules. DNA encoding these proteins are introduced as genes into live animals, plants or microbes, where their activities can be turned on by near-infrared light, controlled by the intensity of light, and turned off by near-infrared light of a different wavelength than the activating light. These proteins can regulate diverse cellular processes with high spatial and temporal precision, in a nontoxic manner, often using external light sources.
    Type: Application
    Filed: July 27, 2012
    Publication date: January 31, 2013
    Applicant: UNIVERSITY OF WYOMING
    Inventors: Mark Gomelsky, Min-Hyung Ryu