Abstract: Compounds of the general formula (I) as described and defined herein, methods for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds and pharmaceutical compositions for the treatment or prevention of diseases, in particular cancer or conditions with dysregulated immune functions, or other conditions associated with aberrant AhR signalling, as a sole agent or in combination with other active ingredients.

Abstract: An eyewear system including an eyewear frame and an application module. The eyewear frame including a docking station, and an electronic connector including a first set of preconfigured application connection points. The application module adapted to be mounted to the docking station, and including an electronic device configured to perform a function, and a second set of preconfigured application connection points corresponding to at least some of the first set of preconfigured application connection points. The second set of preconfigured application connection points including at least two different sub-function connections used to support the function of the electronic device.

Abstract: A system for actuating fluid flow is disclosed. The system includes a fluid actuator, an electric motor for driving the fluid actuator, a motor controller for controlling the motor, a local energy storage device for powering the motor, a stability monitor that assesses instability of operation of the fluid actuator, and a mitigation control that mitigates instability of the fluid actuator via the motor controller based on the assessment of the stability monitor, wherein a response time of the mitigation is faster than changes in fluid flow in the system during fluid actuation.

Abstract: The present disclosure relates to compounds of formula (I), which are suitable as AhR modulators, in particular AhR inhibitors. The disclosure also relates to compositions comprising said compounds and use of said compounds or compositions in treatment, in particular in the treatment of cancer. The disclosure further relates to methods of preparing said compounds.

Abstract: A biopsy device includes a body, a needle, a cutter, and a cutter drive assembly. Body includes an outer housing. The needle extends distally from the body. The cutter is configured to rotate and translate relative to the needle. The cutter drive assembly includes a cutter overmold secured to a portion of the cutter. The cutter overmold includes a threaded portion and one or more channels. The threaded portion is configured to drive translation of the cutter. The one or more channels are configured to drive rotation of the cutter. The outer housing defines a resilient member extending inwardly from an inner surface of the outer housing. The resilient member is configured to engage the cutter overmold to apply either a proximally oriented force or a distally oriented force to the cutter overmold.

Abstract: An eyewear system including an eyewear frame and an application module. The eyewear frame including a docking station, and an electronic connector including a first set of preconfigured application connection points. The application module adapted to be mounted to the docking station, and including an electronic device configured to perform a function, and a second set of preconfigured application connection points corresponding to at least some of the first set of preconfigured application connection points. The second set of preconfigured application connection points including at least two different sub-function connections used to support the function of the electronic device.

Abstract: A control module for use in a magnetic resonance imaging (MRI) guided biopsy procedure using an MRI coil includes a body and a plurality of MRI compatibility features. The body includes one or more ports configured to couple the control module to a biopsy device. The body further includes a display configured to output one or more biopsy device status indicators. The MRI compatibility features are configured to reduce an electromagnetic footprint of the control module.

Abstract: A lid counterbalance assembly for a grill, the grill including a lid and a base, the lid counterbalance assembly including a pulley assembly including at least one pulley, the pulley assembly rotatably connected to the base, a spring connected to the pulley assembly via a first line, and a second line including a first end connected to the pulley assembly and a second end connected to the lid, wherein the second end is rotatable and translatable with respect to the lid.

Abstract: A portable projection turret deployment is provided with a media projection subsystem (MPS). The MPS has a display surface aligned in a vertical plane, as is conventional. At a first time, the MPS display surface is rotated to align in a first horizontal direction, as viewed from a plan (top-down) perspective. Alternatively stated, a horizontal direction is the direction that the MPS display screen faces, or the direction in which the MPS projects visual information. At a second time, the MPS display surface is rotated in a second horizontal direction. The first horizontal direction may be orthogonal to the second horizontal direction. In one aspect, the MPS display surface can be rotated in a plurality of horizontal directions. In another aspect, the MPS display surface can be rotated (spun) in a horizontal circle.

Abstract: An eyewear system including an eyewear frame and an application module. The eyewear frame including a docking station, and an electronic connector including a first set of preconfigured application connection points. The application module adapted to be mounted to the docking station, and including an electronic device configured to perform a function, and a second set of preconfigured application connection points corresponding to at least some of the first set of preconfigured application connection points. The second set of preconfigured application connection points including at least two different sub-function connections used to support the function of the electronic device.

Abstract: A lid counterbalance assembly for a grill, the grill including a lid and a base, the lid counterbalance assembly including a pulley assembly including at least one pulley, the pulley assembly rotatably connected to the base, a spring connected to the pulley assembly via a first line, and a second line including a first end connected to the pulley assembly and a second end connected to the lid, wherein the second end is rotatable and translatable with respect to the lid.

Abstract: A fire display fire pit for burning pelletized fuel and associated components and methods. The fire display pit can include a conveyor for moving pelletized fuel from a hopper to a burn chamber. The fire pit may be configured to produce flames in a vortex pattern, such as inside a flame tower.

Abstract: Eyewear including an optical functional member, control electronics, and a sealed electrical connective element connecting the electronics to the optical functional member. The connective element can directly connect the electronics to the optical functional member, or can connect through an intermediate contact, e.g., a plug-and-receptacle. The connective element can be routed from the electronics, around a rimlock of the eyewear to the optical functional member. The connective element can be a conductive compressible member, such as conductive rubber. In some embodiments, the connective element can be a multiconductor cable.

Abstract: The present disclosure relates to compounds of formula (I). Compounds of formula (II), Compounds of formula (III), Compounds of formula (IV), Compounds of formula (V), Compounds of formula (VI), Compounds of formula (VII), in particular inhibitors if AhR, pharmaceutical formulation comprising any one of the same, use of said compounds or compositions in treatment, in particular treatment of cancer.

Abstract: A biopsy device includes a body, a needle, a cutter, and a cutter drive mechanism. The needle extends distally from the body. The cutter is movable relative to the needle to sever a tissue sample. The cutter drive mechanism is driven by a rotary drive cable and is configured to both rotate and translate the cutter. The cutter drive mechanism is further configured to reverse the transition direction of the cutter wile the drive provided by the rotary drive cable is in a continuous rotary direction.

Abstract: An eyewear system including an eyewear frame and an application module. The eyewear frame including a docking station, and an electronic connector including a first set of preconfigured application connection points. The application module adapted to be mounted to the docking station, and including an electronic device configured to perform a function, and a second set of preconfigured application connection points corresponding to at least some of the first set of preconfigured application connection points. The second set of preconfigured application connection points including at least two different sub-function connections used to support the function of the electronic device.

Abstract: Eyewear including an optical functional member, control electronics, and a sealed electrical connective element connecting the electronics to the optical functional member. The connective element can directly connect the electronics to the optical functional member, or can connect through an intermediate contact, e.g., a plug-and-receptacle. The connective element can be muted from the electronics, around a rimlock of the eyewear to the optical functional member. The connective element can be a conductive compressible member, such as conductive rubber. In some embodiments, the connective element can be a multiconductor cable.

Abstract: A biopsy device includes a probe, a holster, and a probe lock. The probe includes a probe body and a needle extending distally from the probe body. The probe is releasably couplable to the holster. The probe lock includes a lock member configured to move laterally relative to a longitudinal axis defined by the needle to selectively lock the probe to the holster.

Abstract: Improving execution of application program instructions by receiving code having a security classification, determining that the code is untrusted according to the security classification and inserting instructions for a cache flush associated with executing the code.