Abstract: Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an user of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser or high-intensity focused ultrasound probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

Abstract: Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an user of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser or high-intensity focused ultrasound probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

Abstract: In one aspect, recording instruments, probes, probe sheaths, and probe sleeves may include one or more recording elements, such as one or more ECG wires, EEG wires, and/or SEEG wires. A recording element may be used for lesion localization and assessment at the time of cryotherapy, thermal therapy, or temperature modulation therapy. A recording element may be used to provide positioning and monitoring during functional neurosurgery; to apply local tissue stimulation responsive to detection of an abnormal event to regulate cellular behaviors during treatment; to effect deep brain stimulation during a neurosurgical operation; to monitor internal electrical signals and identify abnormalities. Recording instruments may be deployed in vivo for hours or days while monitoring and analyzing signals. For signal analysis, leads disposed between recording element contact surfaces and along a shaft of the recording instrument may deliver recorded signals to a controller external to the patient for analysis.

Abstract: A variable length interstitial probe apparatus includes: a probe for effecting thermal therapy and/or cryotherapy to a tissue; a flexible umbilical sheath permanently affixed to the probe, including at least one interface for supplying energy, cooling fluid, cooling gas, heating fluid, and/or heating gas to the probe; and an adjustable depth stop configured to slide along a length of a shaft region of the probe, and lock to the shaft region at a selected position. The adjustable depth stop is configured to engage a probe driver and/or a skull mount apparatus to stabilize positioning of the probe and to control a depth of entry of the probe into a patient. The probe may be configured to effect temperature modulation therapy, where processing circuitry activates a modulation pattern of thermal therapy emission and cryogenic therapy emission for applying a thermal dose to the tissue.

Abstract: In one aspect, the present disclosure relates to a head fixation apparatus including a number of support posts, and a curved ring portion including a number of connectors configured to adjustably and releasably mount support posts on the lower ring portion, such that the support posts are selectively mounted to a subset of the connectors in a customized arrangement for a patient. The apparatus may include a ring mount configured for fixation to a platform, including a curved channel substantially matching a curvature of the curved ring portion, and a mount locking mechanism for locking the curved ring portion within the channel of the ring mount. The curved ring portion may be configured to rotate within the channel of the ring mount while the ring mount is fixed to the platform, an angular head position of the patient being selectably adjustable while the patient is laying on the platform.

Abstract: In some embodiments, the presentation manager is configured to provide an interface requesting information regarding a proposal from a digital device over a network and receive the information from the digital device. The business object manager is configured to instantiate a business object based on the received information and store the instantiated business object within a data structure residing in a computer readable medium. The business rule manager is configured to generate a business rule associated with the business object, the business rule comprising instructions to perform an operation, the instructions being conditional based on the instantiated business object.

Abstract: In some embodiments, the presentation manager is configured to provide an interface requesting information regarding a proposal from a digital device over a network and receive the information from the digital device. The business object manager is configured to instantiate a business object based on the received information and store the instantiated business object within a data structure residing in a computer readable medium. The business rule manager is configured to generate a business rule associated with the business object, the business rule comprising instructions to perform an operation, the instructions being conditional based on the instantiated business object.

Abstract: A tilt mechanism is configured for adjustment of a tension applied by a chair back. The tilt mechanism includes a base, a back bracket tiltably supported on the base, and a rocker coupled to the back bracket so as to be moveable relative to the back bracket. The rocker has a pivot axis and pivots about the pivot axis when the back bracket tilts relative to the base. An energy storage mechanism is coupled to the rocker to exert a force onto a portion of the rocker. An actuating mechanism is coupled to at least one of the rocker or the energy storage mechanism and is configured to alter a distance between the pivot axis and the portion of the rocker at which the force is exerted onto the rocker, thereby altering a length of a lever arm.

Abstract: A tilt mechanism (10) for a chair comprises a base (11), a first support (12) configured to support a chair seat and a second support (13) configured to support a chair back. The second support (13) is pivotably coupled to the base (11). A first coupling mechanism (41) couples the first support (12) with the base (11) and includes a first pin (40) slideably supported in a first linear guide slot (20). A second coupling mechanism (42) couples the second support (13) with the first support (12) and includes a second pin (44) slideably supported in a second linear guide slot (36). When the second support (13) pivots relative to the base (11), the first pin (40) is caused to be displaced along the first linear guide slot (20) and the second pin (44) is caused to be displaced along the second linear guide slot (36).

Abstract: A tilt mechanism for a chair comprises a base, a first support configured to support a chair seat and a second support configured to support a chair back, the second support is pivotably coupled to the base. A coupling mechanism couples the second support to both the base and the first support. The coupling mechanism comprises a pin attached to the first support, a first linear guide slot provided on the base, and a second linear guide slot provided on the second support. The pin is slideably received in both the first linear guide slot and the second linear guide slot. The second linear guide slot slopes upwardly in a forward direction of the tilt mechanism when the tilt mechanism is in a zero-tilt position.

Abstract: A chair back height adjustment mechanism comprises a guide having an abutment surface at a lateral side of the guide which extends along an adjustment direction. The chair back height adjustment mechanism comprises an adjusting device supported on the guide so as to be displaceable along the adjustment direction. The adjusting device comprises a carrier, a coupling member which is moveably supported on the carrier, and a bias mechanism. The coupling member has a contact face shaped to abut on the abutment surface of the guide and a slanted face. The bias mechanism is operative to apply a force onto the slanted face to urge the contact face of the coupling member against the abutment surface of the guide.

Abstract: Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an user of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser or high-intensity focused ultrasound probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

Abstract: Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an operator of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser or high-intensity focused ultrasound probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

Abstract: Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an operator of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser or high-intensity focused ultrasound probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

Abstract: In one aspect, the present disclosure relates to a head fixation apparatus including a number of support posts, and a curved ring portion including a number of connectors configured to adjustably and releasably mount support posts on the lower ring portion, such that the support posts are selectively mounted to a subset of the connectors in a customized arrangement for a patient. The apparatus may include a ring mount configured for fixation to a platform, including a curved channel substantially matching a curvature of the curved ring portion, and a mount locking mechanism for locking the curved ring portion within the channel of the ring mount. The curved ring portion may be configured to rotate within the channel of the ring mount while the ring mount is fixed to the platform, an angular head position of the patient being selectably adjustable while the patient is laying on the platform.

Abstract: Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an user of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser or high-intensity focused ultrasound probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

Abstract: Thermal monitoring of tissue during a thermal therapy may include identifying an imaging plane bisection axis lying along at least one of a longitudinal axis of a thermal therapy instrument and a vector through a region of interest. The method may include identifying multiple thermal monitoring planes used in monitoring thermal therapy of the volume, where each thermal monitoring plane intersects the region of interest, where a first thermal monitoring plane intersects a second thermal monitoring plane at the imaging plane bisection axis, and the first thermal monitoring plane is offset from the second thermal monitoring plane by an angle of intersection. The method may include and performing thermal monitoring of the thermal therapy by obtaining magnetic resonance (MR) images obtained from the first monitoring plane and the second monitoring plane, and calculating, based on the images, temperature data of the volume.

Abstract: Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an operator of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

Abstract: In some embodiments, the presentation manager is configured to provide an interface requesting information regarding a proposal from a digital device over a network and receive the information from the digital device. The business object manager is configured to instantiate a business object based on the received information and store the instantiated business object within a data structure residing in a computer readable medium. The business rule manager is configured to generate a business rule associated with the business object, the business rule comprising instructions to perform an operation, the instructions being conditional based on the instantiated business object.

Abstract: In some embodiments, the presentation manager is configured to provide an interface requesting information regarding a proposal from a digital device over a network and receive the information from the digital device. The business object manager is configured to instantiate a business object based on the received information and store the instantiated business object within a data structure residing in a computer readable medium. The business rule manager is configured to generate a business rule associated with the business object, the business rule comprising instructions to perform an operation, the instructions being conditional based on the instantiated business object.