Patents by Inventor Mark Guzman

Mark Guzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphic and amorphous forms of 2-{3-[(E)-2-(4,6-dimethyl-pyridin-2-yl)-vinyl]-1H-indazol-6-ylamino}-N-(4-hydroxy-but-2-ynyl)benzamide
    Publication number: 20060160863
    Abstract: This invention provides several crystalline polymorphic forms, amorphous forms, and mixtures thereof of the compound of Formula I: and pharmaceutical compositions made therewith, and to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions, to treat ophthalmic diseases, such as age related macular degeneration and other diseases associated with unwanted ocular angiogenesis.
    Type: Application
    Filed: December 14, 2005
    Publication date: July 20, 2006
    Inventors: Tim Edward Alcacio, Winnie Hoyan Chan, Mark Guzman, Asayuki Kamatani, Cynthia Palmer, Nabil Saeed, Jill Melissa Scott, Jayaram Kasturi Srirangam
  • Method for preparing indan-1,3-dicarboxylic acid
    Publication number: 20050240057
    Abstract: A method for preparing indan-1,3-dicarboxylic acid compounds which are useful intermediates in the syntheses of aryl fused azapolycyclic compounds as agents for the treatment of neurological and psychological disorders.
    Type: Application
    Filed: November 12, 2003
    Publication date: October 27, 2005
    Inventors: Timothy Watson, Mark Guzman, Patrice Arpin
  • Pyrrolinone-based peptidomimetics
    Patent number: 5770732
    Abstract: Novel pyrrolinone-based compounds mimic or inhibit the biological and/or chemical activity of peptides, including peptide .beta.-strand conformations. Certain compounds contain functionalized pyrrolinone units in place of one or more amino acids of a target peptide.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: June 23, 1998
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Ralph F. Hirschmann, Amos B. Smith, III, Paul Sprengeler, Ryan C. Holcomb, Terence Keenan, John L. Wood, Mark Guzman, Alexander Pasternak
  • Pyrrolinone-based compounds
    Patent number: 5489692
    Abstract: Novel pyrrolinone-based compounds mimic or inhibit the biological and/or chemical activity of peptides, including peptide .beta.-strand conformations. Certain compounds contain functionalized pyrrolinone units in place of one or more amino acids of a target peptide.
    Type: Grant
    Filed: February 17, 1993
    Date of Patent: February 6, 1996
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Ralph Hirschmann, Amos B. Smith, III, Paul Sprengeler, Ryan C. Holcomb, Terence Keenan, John L. Wood, Mark Guzman