Abstract: A medicament dispenser comprising a canister and a drug dispensing valve, wherein one or more surfaces of said canister and/or valve has a fluorinated coating provided by a process comprising generating one or more fluorine-containing radical species and polymerising said radicals on said one or more surfaces, provided that the radicals are generated by a hot filament chemical vapour process, pyrolisation of fluoroparylene dimers, use of a photo initiator to create radicals from a fluoroacrylate or laser ablation of a fluoropolymer target. Also disclosed is a medicament dispenser comprising a canister and a drug-dispensing valve, wherein one or more surfaces of said canister and/or valve has a fluorinated coating provided by a process comprising incorporating a fluorine-containing species into a liquid or gas, depositing a fluorine-containing layer on said one or more surfaces, and thereafter optionally removing the liquid or gas.

Abstract: There is provided according to the invention a component or accessory for use in a metered dose inhaler for dispensing a medicament in a fluid propellant, the component or accessory having a medicament interface comprising a treated surface and an untreated surface. There are also provided processes for its preparation and its use in therapy.