Patents by Inventor Mark Hartell

Mark Hartell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artemisinins with improved stability and bioavailability for therapeutic drug development and application
    Publication number: 20060229279
    Abstract: A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, ?-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic decomposition rendering it stable in solution. Artelinic acid and cyclodextrin are placed into contact with one another to yield a 2:1 molecular species. Artesunic acid and cyclodextrin yield a 1:1 molecular species. The complexed cyclodextrin artemisinin formulation is effective for the treatment of malaria and is stable in solution for long periods of time.
    Type: Application
    Filed: June 9, 2006
    Publication date: October 12, 2006
    Inventors: Mark Hartell, Apurba Bhattacharjee, Rickey Hicks, John VanHamont, Wilbur Milhous
  • Artemisinins with improved stability and bioavailability for therapeutic drug development and application
    Publication number: 20050187189
    Abstract: A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, ?-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic decomposition rendering it stable in solution. Artelinic acid and cyclodextrin are placed into contact with one another to yield a 2:1 molecular species. Artesunic acid and cyclodextrin yield a 1:1 molecular species. The complexed cyclodextrin artemisinin formulation is effective for the treatment of malaria and is stable in solution for long periods of time.
    Type: Application
    Filed: April 25, 2005
    Publication date: August 25, 2005
    Inventors: Mark Hartell, Apurba Bhattacharjee, Rickey Hicks, John VanHamont, Wilbur Milhous