Abstract: Provided herein is technology relating to sequencing nucleic acids and particularly, but not exclusively, to devices, methods, and systems for sequencing-by-synthesis using changes in pH to monitor base addition.

Abstract: Provided herein is technology relating to sequencing nucleic acids and particularly, but not exclusively, to devices, methods, and systems for sequencing-by-synthesis using changes in pH to monitor base addition. In some embodiments the electrochemical hydrogen ion sensor is a microfabricated mixed metal oxide electrode and in some embodiments the electrochemical hydrogen ion sensor is a membrane electrode. Moreover, in some embodiments the device further comprises a reference electrode. Performing the sequencing reaction involves moving solutions and other fluids (e.g., samples, nucleotide solutions, wash solutions) into and out of the reaction vessel. Thus, in some embodiments, the device further comprises a tube or other transport mechanism or pathway attached to the reaction vessel.

Abstract: Provided herein is technology relating to sequencing nucleic acids and particularly, but not exclusively, to devices, methods, and systems for sequencing-by-synthesis using changes in pH to monitor base addition. In some embodiments the electrochemical hydrogen ion sensor is a microfabricated mixed metal oxide electrode and in some embodiments the electrochemical hydrogen ion sensor is a membrane electrode. Moreover, in some embodiments the device further comprises a reference electrode. Performing the sequencing reaction involves moving solutions and other fluids (e.g., samples, nucleotide solutions, wash solutions) into and out of the reaction vessel. Thus, in some embodiments, the device further comprises a tube or other transport mechanism or pathway attached to the reaction vessel.

Abstract: The present invention provides a lacrosse stick (220) comprising a unibody head and shaft construction that increases lacrosse throwing accuracy and power.

Abstract: A distributed network storage system provides capability to send and receive storage information from multiple network storage servers in a storage area network using iSCSI commands. A storage server system comprising at least two data storage servers stores one or more logical volumes of data. A host computer receives a storage command from a host application, and determines one or more data storage servers has information to complete the storage command. The host computer generates one or more iSCSI network commands to carry out the storage command, and transmits the iSCSI network commands directly to each data storage server having necessary information. The storage servers receive iSCSI network commands, and return a response to the host. The host and storage servers verify the configuration of the storage network and are capable of correcting or updating the configuration as required.

Abstract: A data storage system including a primary data storage device and a backup data storage device stores data with enhanced performance. The primary data storage device has a primary data storage device memory for holding data, and the backup data storage device has a backup volatile memory, a backup non-volatile memory, and a processor. The backup storage device processor causes a copy of data provided to the primary data storage device to be provided to the backup data storage device volatile memory, and in the event of a power interruption moves the data from the backup volatile memory to the backup non-volatile memory. In such a manner, data stored at the backup data storage device is not lost in the event of a power interruption.

Abstract: A method for copying data and a data storage system including a primary data storage system and a remote data storage system stores data and copies data between the primary and remote systems with enhanced performance. The primary data storage system includes a primary data storage volume, and primary snapshots comprising data stored at the primary volume since a previous primary snapshot. The remote system includes a remote volume comprising a pointer to one or more remote snapshots, the remote snapshots corresponding to the primary snapshots. In the event of a failure at the primary system, the remote volume is made into a new primary volume and data from the remote snapshots is used for read and write operations in place of the primary volume. When the primary volume recovers from the failure, the new primary volume may be resynchronized with the primary volume.

Abstract: The present invention provides a lacrosse stick comprising a unibody head and shaft construction.

Abstract: The present invention provides a lacrosse stick comprising a unibody head and shaft construction that increases lacrosse throwing accuracy and power.

Abstract: The present invention provides an improved lacrosse shaft head connection. In particular, the present invention provides a lacrosse head with a male plug to fit in a female socket of a lacrosse shaft. Further, the lacrosse head of the present invention may be strategically designed with sidewall placements to guide a lacrosse ball to a desired location.

Abstract: The present invention provides a lacrosse shaft. The lacrosse shaft has an integral or interlocked end stop to inhibit stoppage.

Abstract: The present invention provides an athletic glove. The athletic glove has an improved padding construction to allow for increased flexibility of the glove. The improved padding construction includes a crescent shaped pad aligned with the middle and index finger. The glove also provides improved palm constructions to improve moisture management and grip. The improved construction includes using moisture or temperature management fabric in strategic locations on the palm or an open palm construction to allow direct contact between a player's palm and the shaft of an athletic stick.

Abstract: A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS193 and transcribed from GI tract tissue, are described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS193-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS193 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.

Abstract: A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS141 and transcribed from GI tract tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS141-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS141 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.

Abstract: Abstract of the Disclosure The present invention is directed to a data storage system for use in achieving distributed data storage over a computer network. One embodiment of the data storage system comprises a storage server system that is comprised of one or more storage servers that each provide data storage, a management server system that is comprised of one or more management servers that each provide management functionality relating to the storage server system, and a driver that is capable of being associated each of the application clients that are to utilize the data storage system. A data storage configuration identifier structure whose value is updated when there is a change to the composition of the storage system or storage allocation within the storage system is used to manage data transfers between the storage system and application clients.

Abstract: The present invention relates to an improved sports shaft. The improved shaft is comprised of a synthetic material designed to minimize weight and provide other desirable characteristics. The shaft may include a unique outwardly expanded portion that dramatically improves the shaft's performance. The outwardly expanded portion expands lengthwise and widthwise to create a wider portion that accommodates a player's hand position. The outer surface of the shaft may be coated with a gripable material to improve the overall grip and feel characteristics of the shaft.

Abstract: The present invention relates to an improved sports shaft. The improved shaft is comprised of a synthetic material designed to minimize weight and provide a desirable amount of flex. The shaft may include a unique tapered grip portion that dramatically improves the shaft's flex and feel characteristics. The tapered grip portion is tapered lengthwise and widthwise to create a narrower portion that accommodates a player's hand position. The outer surface of the shaft is coated with a gripable material to improve the overall grip and feel characteristics of the shaft. The gripable material comprises a low coefficient of thermal surface conductivity. In addition, the outer coating creates an aesthetically pleasing appearance in comparison with an uncoated aluminum shaft.

Abstract: A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS197 and transcribed from GI tract tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS197-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS197 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.

Abstract: The present invention is directed to a data storage system for use in achieving distributed data storage over a computer network. One embodiment of the data storage system comprises a storage server system that is comprised of one or more storage servers that each provide data storage, a management server system that is comprised of one or more management servers that each provide management functionality relating to the storage server system, and a driver that is capable of being associated each of the application clients that are to utilize the data storage system. A data storage configuration identifier structure whose value is updated when there is a change to the composition of the storage system or storage allocation within the storage system is used to manage data transfers between the storage system and application clients.

Abstract: A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS 197 and transcribed from GI tract tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS 197-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS 197 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.