Patents by Inventor Mark Heffernan

Mark Heffernan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of growth hormone receptor expression and insulin-like growth factor expression
    Publication number: 20050282761
    Abstract: Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides, targeted to nucleic acid encoding growth hormone receptor. Methods of using these compounds for modulation of growth hormone receptor expression and for diagnosis and treatment of disease associated with expression of growth hormone receptor and/or insulin-like growth factor-I are provided. Diagnostic methods and kits are also provided.
    Type: Application
    Filed: August 25, 2004
    Publication date: December 22, 2005
    Inventors: George Tachas, Kenneth Dobie, Ravi Jain, Christopher Belyea, Mark Heffernan
  • Modulation of growth hormone receptor expression and insulin-like growth factor expression
    Publication number: 20040253723
    Abstract: Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides, targeted to nucleic acid encoding growth hormone receptor. Methods of using these compounds for modulation of growth hormone receptor expression and for diagnosis and treatment of disease associated with expression of growth hormone receptor and/or insulin-like growth factor-I are provided. Diagnostic methods and kits are also provided.
    Type: Application
    Filed: February 26, 2004
    Publication date: December 16, 2004
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: George Tachas, Kenneth W. Dobie, Ravi Jain, Christopher Belyea, Mark A. Heffernan
  • Product and method for control of obesity
    Publication number: 20040014639
    Abstract: This invention relates to the prevention and treatment of obesity in mammals, especially humans. In particular, the invention relates to a method of treating obesity in a mammal, comprising the step of administering to the mammal a therapeutically-effective amount of an agent which increases the expression of beta-3 adrenergic receptors in the mammal, together with an agonist of the beta 3 adrenergic receptor.
    Type: Application
    Filed: August 14, 2003
    Publication date: January 22, 2004
    Inventors: Christopher Ian Belyea, Mark Heffernan, Roger Summers