Patents by Inventor Mark Hewko
Mark Hewko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150112192Abstract: Methods for assessing blood flow in vasculature in a portion of tissue in an animal may include administering a fluorescent dye to the animal such that the fluorescent dye enters the portion of tissue, exciting the fluorescent dye within the portion of tissue with a source of illumination such that the fluorescent dye emits radiation, capturing the radiation emitted by the fluorescent dye with a camera capable of capturing a series of angiographic images within the portion of tissue, and evaluating the series of angiographic images to assess blood flow in the vasculature in the tissue portion.Type: ApplicationFiled: November 17, 2014Publication date: April 23, 2015Inventors: John C. DOCHERTY, Mark HEWKO, Gurpreet MANGAT, Robert W. FLOWER, Seshadri M. CHARI
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Publication number: 20150112193Abstract: Methods for assessing perfusion in a portion of tissue in an animal may include administering a fluorescent dye to the animal such that the fluorescent dye enters the portion of tissue, exciting the fluorescent dye within the portion of tissue with a source of illumination such that the fluorescent dye emits radiation, capturing the radiation emitted by the fluorescent dye with a camera, and obtaining at least one image of the fluorescence radiation emitted from the portion of tissueType: ApplicationFiled: November 17, 2014Publication date: April 23, 2015Inventors: John C. DOCHERTY, Mark HEWKO, Gurpreet MANGAT, Robert W. FLOWER, Seshadri M. CHARI
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Publication number: 20130053690Abstract: Method for assessing the patency of a patient's blood vessel, advantageously during or after treatment of that vessel by an invasive procedure, comprising administering a fluorescent dye to the patient; obtaining at least one angiographic image of the vessel portion; and evaluating the at least one angiographic image to assess the patency of the vessel portion. Other related methods are contemplated, including methods for assessing perfusion in selected body tissue, methods for evaluating the potential of vessels for use in creation of AV fistulas, methods for determining the diameter of a vessel, and methods for locating a vessel located below the surface of a tissue.Type: ApplicationFiled: March 13, 2012Publication date: February 28, 2013Inventors: John C. DOCHERTY, Mark Hewko, Gurpreet Mangat, Robert W. Flower, Seshadri M. Chari
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Patent number: 7881777Abstract: Method for assessing the patency of a patient's blood vessel, advantageously during or after treatment of that vessel by an invasive procedure, comprising administering a fluorescent dye to the patient; obtaining at least one angiographic image of the vessel portion; and evaluating the at least one angiographic image to assess the patency of the vessel portion. Other related methods are contemplated, including methods for assessing perfusion in selected body tissue, methods for evaluating the potential of vessels for use in creation of AV fistulas, methods for determining the diameter of a vessel, and methods for locating a vessel located below the surface of a tissue.Type: GrantFiled: November 28, 2007Date of Patent: February 1, 2011Assignee: National Research Council of CanadaInventors: John C. Docherty, Mark Hewko, Gurpreet Mangat, Robert W. Flower, Seshadri M. Chari
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Patent number: 7860554Abstract: A non-invasive method of characterizing burn injuries using near infrared spectroscopy is described. In the method, a beam of light is emitted into the burnt tissue portion at two or more different tissue depths. The spectra are then compared using multivariate analysis to determine diagnostic regions of the spectra. This information is used to categorize the burn. In some cases, the diagnostic regions correspond to wavelengths related to the hemodynamics of the tissue portion. The spectra can also be repeated over time, thereby allowing trends and changes in the spectra to be measured. This data is in turn used to categorize the burn as either a superficial burn, partial thickness burn, deep partial burn or a full thickness burn. Once the burn has been categorized, the clinician can intervene as needed to treat the burn.Type: GrantFiled: January 26, 2001Date of Patent: December 28, 2010Assignee: National Research Council of CanadaInventors: Lorenzo Leonardi, Jerl Payette, Michael G. Sowa, Mark Hewko, Bernhard J. Schattka, Henry H. Mantsch
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Patent number: 7796243Abstract: Early dental caries detection is carried out by a method that combines optical coherence tomography (OCT) and Raman spectroscopy to provide morphological information and biochemical specificity for detecting and characterizing incipient carious lesions found in extracted human teeth. OCT imaging of tooth samples demonstrated increased light back-scattering intensity at sites of carious lesions as compared to the sound enamel. Raman microspectroscopy and fibre-optic based Raman spectroscopy are used to characterize the caries further by detecting demineralization-induced alterations of enamel crystallite morphology and/or orientation. OCT imaging is useful for screening carious sites and determining lesion depth, with Raman spectroscopy providing biochemical confirmation of caries. The combination is incorporated into a common probe operable without movement to scan the tooth surface and to provide an output for the dentist.Type: GrantFiled: June 9, 2005Date of Patent: September 14, 2010Assignees: National Research Council of Canada, Dalhousie University, University of ManitobaInventors: Lin-P'ing Choo-Smith, Alex C. T. Ko, Mark Hewko, Lorenzo Leonardi, Blaine Cleghorn, Cecilia Dong
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Publication number: 20080071176Abstract: Method for assessing the patency of a patient's blood vessel, advantageously during or after treatment of that vessel by an invasive procedure, comprising administering a fluorescent dye to the patient; obtaining at least one angiographic image of the vessel portion; and evaluating the at least one angiographic image to assess the patency of the vessel portion. Other related methods are contemplated, including methods for assessing perfusion in selected body tissue, methods for evaluating the potential of vessels for use in creation of AV fistulas, methods for determining the diameter of a vessel, and methods for locating a vessel located below the surface of a tissue.Type: ApplicationFiled: November 28, 2007Publication date: March 20, 2008Applicant: National Research Council of CanadaInventors: John Docherty, Mark Hewko, Gurpreet Mangat, Robert Flower, Seshadri Chari
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Publication number: 20060155193Abstract: A non-invasive method of characterizing burn injuries using near infrared spectroscopy is described. In the method, a beam of light is emitted into the burnt tissue portion at two or more different tissue depths. The spectra are then compared using multivariate analysis to determine diagnostic regions of the spectra. This information is used to categorize the burn. In some cases, the diagnostic regions correspond to wavelengths related to the hemodynamics of the tissue portion. The spectra can also be repeated over time, thereby allowing trends and changes in the spectra to be measured. This data is in turn used to categorize the burn as either a superficial burn, partial thickness burn, deep partial burn or a full thickness burn. Once the burn has been categorized, the clinician can intervene as needed to treat the burn.Type: ApplicationFiled: January 26, 2001Publication date: July 13, 2006Applicant: National Research Center of CanadaInventors: Lorenzo Leonardi, Jerl Payette, Michael Sowa, Mark Hewko, Bernhard Schattka, Henry Mantsch
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Publication number: 20050283058Abstract: Early dental caries detection is carried out by a method that combines optical coherence tomography (OCT) and Raman spectroscopy to provide morphological information and biochemical specificity for detecting and characterizing incipient carious lesions found in extracted human teeth. OCT imaging of tooth samples demonstrated increased light back-scattering intensity at sites of carious lesions as compared to the sound enamel. Raman microspectroscopy and fibre-optic based Raman spectroscopy are used to characterize the caries further by detecting demineralization-induced alterations of enamel crystallite morphology and/or orientation. OCT imaging is useful for screening carious sites and determining lesion depth, with Raman spectroscopy providing biochemical confirmation of caries. The combination is incorporated into a common probe operable without movement to scan the tooth surface and to provide an output for the dentist.Type: ApplicationFiled: June 9, 2005Publication date: December 22, 2005Inventors: Lin-P'ing Choo-Smith, Alex Ko, Mark Hewko, Lorenzo Leonardi, Blaine Cleghorn, Cecilia Dong
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Publication number: 20050182434Abstract: Method for assessing the patency of a patient's blood vessel, advantageously during or after treatment of that vessel by an invasive procedure, comprising administering a fluorescent dye to the patient; obtaining at least one angiographic image of the vessel portion; and evaluating the at least one angiographic image to assess the patency of the vessel portion. Other related methods are contemplated, including methods for assessing perfusion in selected body tissue, methods for evaluating the potential of vessels for use in creation of AV fistulas, methods for determining the diameter of a vessel, and methods for locating a vessel located below the surface of a tissue.Type: ApplicationFiled: April 14, 2005Publication date: August 18, 2005Applicant: National Research Council of CanadaInventors: John Docherty, Mark Hewko, Gurpreet Mangat, Robert Flower, Seshadri Chari
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Patent number: 6915154Abstract: Method for assessing the patency of a patient's blood vessel, advantageously during or after treatment of that vessel by an invasive procedure, comprising administering a fluorescent dye to the patient; obtaining at least one angiographic image of the vessel portion; and evaluating the at least one angiographic image to assess the patency of the vessel portion. Other related methods are contemplated, including methods for assessing perfusion in selected body tissue, methods for evaluating the potential of vessels for use in creation of AV fistulas, methods for determining the diameter of a vessel, and methods for locating a vessel located below the surface of a tissue.Type: GrantFiled: August 11, 2000Date of Patent: July 5, 2005Assignee: National Research Council of CanadaInventors: John C. Docherty, Mark Hewko, Gurpreet Mangat, Robert W. Flower, Seshadri M. Chari