Patents by Inventor Mark Howell

Mark Howell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260041808
    Abstract: Methodology for increasing efficiency of a pathogen inactivation via enhancing UVC light absorption at such pathogen by multiple diffuse scattering of the light at a wall defining a substantially closed volume, thereby increasing a number of angles at which the pathogen is being irradiate as compared with a direct irradiation of the pathogen with a beam of such light.
    Type: Application
    Filed: October 20, 2025
    Publication date: February 12, 2026
    Inventors: Dmitri VORONIN, Shyam MOHAPATRA, Subhra MOHAPATRA, Sharad AMBARDAR, Mark HOWELL, Karthick MAYILSAMY
  • Patent number: 12447225
    Abstract: Method for increasing efficiency of a pathogen inactivation via enhancing UVC light absorption at such pathogen by multiple diffuse scattering of the light at a wall defining a substantially closed volume, thereby increasing a number of angles at which the pathogen is being irradiate as compared with a direct irradiation of the pathogen with a beam of such light.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: October 21, 2025
    Assignee: University of South Florida
    Inventors: Dmitri Voronin, Shyam Mohapatra, Subhra Mohapatra, Sharad Ambardar, Mark Howell, Karthick Mayilsamy
  • Publication number: 20240286967
    Abstract: The present disclosure relates generally to carbon-based products. More particularly, the present disclosure relates to acid-impregnated carbon-based products having at least one nitrogen-containing compound covalently bound to a porous carbon matrix, methods of making same, and uses of same in industry and agriculture.
    Type: Application
    Filed: February 28, 2024
    Publication date: August 29, 2024
    Inventors: Mitchel Flegel, Cristine Selirio, Prem Pokharel, Mark Howell, Robert Mackie
  • Publication number: 20220409765
    Abstract: Method for increasing efficiency of a pathogen inactivation via enhancing UVC light absorption at such pathogen by multiple diffuse scattering of the light at a wall defining a substantially closed volume, thereby increasing a number of angles at which the pathogen is being irradiate as compared with a direct irradiation of the pathogen with a beam of such light.
    Type: Application
    Filed: June 27, 2022
    Publication date: December 29, 2022
    Inventors: Dmitri VORONIN, Shyam MOHAPATRA, Subhra MOHAPATRA, Sharad AMBARDAR, Mark HOWELL, Karthick MAYILSAMY
  • Patent number: 11451186
    Abstract: A renewable-energy electrical generation and distribution system including a first container and a second container. Each of the first container and the second container includes a power source disposed within the container and deployable therefrom, and generating energy from a renewable resource. A first compartment is disposed within the container, and retains a battery in communication with the power source. A power distribution system is disposed within the container and in communication with the battery and with the power source. A communications system is disposed within the container and configured to communicate data via an ad-hoc mobile communications network formed by the first container and the second container and configured to operate independent of any communication network not part of the first container and the second container forming the ad-hoc mobile communications network.
    Type: Grant
    Filed: January 4, 2022
    Date of Patent: September 20, 2022
    Assignee: Amenergy, Inc.
    Inventors: Fredric L Milder, Peter Page, Mark Howell
  • Publication number: 20220131496
    Abstract: A renewable-energy electrical generation and distribution system including a first container and a second container. Each of the first container and the second container includes a power source disposed within the container and deployable therefrom, and generating energy from a renewable resource. A first compartment is disposed within the container, and retains a battery in communication with the power source. A power distribution system is disposed within the container and in communication with the battery and with the power source. A communications system is disposed within the container and configured to communicate data via an ad-hoc mobile communications network formed by the first container and the second container and configured to operate independent of any communication network not part of the first container and the second container forming the ad-hoc mobile communications network.
    Type: Application
    Filed: January 4, 2022
    Publication date: April 28, 2022
    Inventors: Fredric L MILDER, Peter PAGE, Mark HOWELL
  • Patent number: 11245351
    Abstract: A renewable-energy electrical generation and distribution system including a container. At least one power source is sized to be retained within the container and deployable therefrom, the at least one power source being configured to generate energy from renewable resources. A battery is disposed within the container and in communication with the at least one power source. A power distribution system is disposed within the container and in communication with the battery and the at least one power source, the power distribution system including: at least one switch and at least one interface connected to the at least one switch and disposed external to the container, the at least one switch configured selectively turn on and off power distribution to the at least one interface based on at least one predetermined parameter.
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: February 8, 2022
    Assignee: Amenergy, Inc.
    Inventors: Fredric L Milder, Peter Page, Mark Howell
  • Patent number: 10813935
    Abstract: Disclosed herein are compositions and methods for treating cancer. Further provided herein are compositions and methods for reducing, inhibiting, or preventing resistance of cancer to tyrosine kinase inhibitors. The methods may include administering an anti-resistance agent such as a CYP51A1 inhibitor or an agonist of miRNA-764 (SEQ ID NO: 4) to a subject. A tyrosine kinase inhibitor may also be administered to the subject in addition to the anti-resistance agent.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: October 27, 2020
    Assignees: TRANSGENEX NANOBIOTECH, INC., University of South Florida
    Inventors: Subhra Mohapatra, Shyam S. Mohapatra, Mark Howell, Rajesh Nair
  • Publication number: 20200119683
    Abstract: A renewable-energy electrical generation and distribution system including a container. At least one power source is sized to be retained within the container and deployable therefrom, the at least one power source being configured to generate energy from renewable resources. A battery is disposed within the container and in communication with the at least one power source. A power distribution system is disposed within the container and in communication with the battery and the at least one power source, the power distribution system including: at least one switch and at least one interface connected to the at least one switch and disposed external to the container, the at least one switch configured selectively turn on and off power distribution to the at least one interface based on at least one predetermined parameter.
    Type: Application
    Filed: October 8, 2019
    Publication date: April 16, 2020
    Inventors: Fredric L. MILDER, Peter PAGE, Mark HOWELL
  • Patent number: 10587703
    Abstract: Technology for providing communication connectivity between network entities located in different isolated communication networks through a centralized cloud service. A cloud service connector in a source communication network receives an initial connection request from a source end point device in the source communication network, and determines a customer name and requested service associated with the port number indicated in the request. Mappings are established between the source end point device and a destination end point device that provides the requested service from within a destination communication network that is associated with the customer name.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: March 10, 2020
    Assignee: Citrix Systems, Inc.
    Inventors: Ricardo Fernando Feijoo, Kenneth Bell, Mark Howell, Manbir Chauhan
  • Publication number: 20190058768
    Abstract: Technology for providing communication connectivity between network entities located in different isolated communication networks through a centralized cloud service. A cloud service connector in a source communication network receives an initial connection request from a source end point device in the source communication network, and determines a customer name and requested service associated with the port number indicated in the request. Mappings are established between the source end point device and a destination end point device that provides the requested service from within a destination communication network that is associated with the customer name.
    Type: Application
    Filed: January 19, 2018
    Publication date: February 21, 2019
    Inventors: Ricardo Fernando Feijoo, Kenneth Bell, Mark Howell, Manbir Chauhan
  • Publication number: 20180256579
    Abstract: Disclosed herein are compositions and methods for treating cancer. Further provided herein are compositions and methods for reducing, inhibiting, or preventing resistance of cancer to tyrosine kinase inhibitors. The methods may include administering an anti-resistance agent such as a CYP51A1 inhibitor or an agonist of miRNA-764 (SEQ ID NO: 4) to a subject. A tyrosine kinase inhibitor may also be administered to the subject in addition to the anti-resistance agent.
    Type: Application
    Filed: February 23, 2018
    Publication date: September 13, 2018
    Inventors: Subhra Mohapatra, Shyam S. Mohapatra, Mark Howell, Rajesh Nair
  • Patent number: 9730691
    Abstract: A staple clip for providing an attachment function in a surgical procedure is described. A center hub has a center hub aperture. The center hub defines a lateral hub plane. A plurality of joining legs each has an inner leg end attached to the center hub and an outer foot defining a lateral foot plane. The inner leg end and outer foot are separated along the leg by an elongate leg body extending laterally outward and longitudinally downward from the center hub. A plurality of lobe pads are attached to the center hub and lie substantially within the lateral hub plane. The inner leg ends and lobe pads alternate with each other around a periphery of the center hub.
    Type: Grant
    Filed: February 12, 2014
    Date of Patent: August 15, 2017
    Assignee: The Cleveland Clinic Foundation
    Inventors: Eric E. Roselli, Ryan S. Klatte, Mark S. Lobosky, Mark Howell
  • Publication number: 20140224858
    Abstract: A staple clip for providing an attachment function in a surgical procedure is described. A center hub has a center hub aperture. The center hub defines a lateral hub plane. A plurality of joining legs each has an inner leg end attached to the center hub and an outer foot defining a lateral foot plane. The inner leg end and outer foot are separated along the leg by an elongate leg body extending laterally outward and longitudinally downward from the center hub. A plurality of lobe pads are attached to the center hub and lie substantially within the lateral hub plane. The inner leg ends and lobe pads alternate with each other around a periphery of the center hub.
    Type: Application
    Filed: February 12, 2014
    Publication date: August 14, 2014
    Applicant: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Eric E. Roselli, Ryan S. Klatte, Mark S. Lobosky, Mark Howell
  • Patent number: 7992325
    Abstract: The subject invention improves traditional safety equipment intended to protect the lower leg, ankle, foot, and toes applicable in industrial and commercial as well as casual and athletic uses. The personal protective equipment (PPE) of the subject invention comprises a soleplate, a metatarsal component, a toe cap, and a tibia-fibula component; these components can be implemented alone or in combination within a shoe or boot providing for various levels of protection depending on the desired application. Further embodiments provide for both the implementation of the protective components within the footwear as well as components that can be worn in conjunction with pre-existing shoes or boots.
    Type: Grant
    Filed: November 5, 2007
    Date of Patent: August 9, 2011
    Assignee: Shew, Inc.
    Inventors: Van T. Walworth, David B. Hook, Thomas Leonard, Craig Whitaker, James F. Walworth, Brian Church, Dave Goldman, Mark Howell
  • Publication number: 20080115387
    Abstract: The subject invention improves traditional safety equipment intended to protect the lower leg, ankle, foot, and toes applicable in industrial and commercial as well as casual and athletic uses. The personal protective equipment (PPE) of the subject invention comprises a soleplate, a metatarsal component, a toe cap, and a tibia-fibula component; these components can be implemented alone or in combination within a shoe or boot providing for various levels of protection depending on the desired application. Further embodiments provide for both the implementation of the protective components within the footwear as well as components that can be worn in conjunction with pre-existing shoes or boots.
    Type: Application
    Filed: November 5, 2007
    Publication date: May 22, 2008
    Inventors: Van T. Walworth, David B. Hook, Thomas Leonard, Craig Whitaker, James F. Walworth, Brian Church, Dave Goldman, Mark Howell
  • Publication number: 20070250183
    Abstract: A system and method for reintegration of a redundant controller after occurrence of a fault is provided, comprising synchronizing outputs of a primary controller with outputs of secondary controllers. The controller is placed in a different mode of operation in which its output is not used in system control. A meta-controller is activated to drive the primary controller to the same states at which the secondary or redundant controllers operate. A voting mechanism is used to determine a fault in an output to a controlled device. Control of the device using the secondary outputs is effected. The primary controller recalculates the primary output, based upon the primary output; a feedback signal; and, the secondary outputs. Control using the primary output is permitted when the primary output is within an allowable range of the secondary outputs.
    Type: Application
    Filed: April 24, 2006
    Publication date: October 25, 2007
    Inventors: Mark Howell, Pradyumna Mishra
  • Publication number: 20070065514
    Abstract: The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors such as soluble TNF receptor from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) such as TNF? muteins capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as a TNF? mutein, capable of specifically binding to a targeted immune system inhibitor such as soluble TNF receptor.
    Type: Application
    Filed: September 22, 2005
    Publication date: March 22, 2007
    Inventor: Mark Howell
  • Publication number: 20070067078
    Abstract: A system and related method for monitoring the state of health of sensors in an integrated vehicle stability control system. In one embodiment, the system determines whether a yaw rate sensor, a lateral acceleration sensor or a hand-wheel angle sensor has failed. The system uses a plurality of models to generate estimates of the outputs of the sensors based on the actual sensor measurements. Residuals are generated as the difference between the measured value and each of the estimates for the particular sensor. The residuals are compared to a threshold to determine whether a fault flag will be set for each residual. The threshold for the hand-wheel angle sensor is an adaptive threshold because it does not have physical redundancy. If the fault flags for the residuals for each sensor have a particular pattern, then a fault is output for that sensor.
    Type: Application
    Filed: September 16, 2005
    Publication date: March 22, 2007
    Inventors: Mutasim Salman, Mark Howell
  • Publication number: 20070061126
    Abstract: The system and method of the present invention is directed to emulating and configuring any of a plurality of electronic input devices. A system in accordance with one embodiment of the present invention comprises an interface and an emulator. The interface is for selecting and configuring an electronic input device from a plurality of electronic input devices, and the emulator is for emulating the electronic input device. Preferably, the plurality of electronic input devices comprise any two or more of a scroll wheel, a mouse, a joy stick, a steering wheel, an analog button, and a touch bar. Also in a preferred embodiment, the interface is an Application Programming Interface (API) and the emulator comprises a finger swipe sensor for receiving user input.
    Type: Application
    Filed: September 1, 2005
    Publication date: March 15, 2007
    Inventors: Anthony Russo, Frank Chen, Mark Howell, Hung Ngo, Marcia Tsuchiya, David Weigand