Abstract: A dental cleansing device includes an elongated hand grip member with an internal space that has a closed end and an open end, an elongated cover member with an insert end that can be connected detachably to the open end of the hand grip member, a holding end that is located opposite to the insert end, and a brush unit. The brush unit is provided on the holding end of the cover member and includes a brush seat which is fastened detachably to the holding end, a brush body integrally formed with the brush seat, and a plurality of hard and soft threads mixed together and wound along the brush body.