Patents by Inventor Mark Huffman
Mark Huffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250136954Abstract: The present invention provides engineered nucleoside deoxyribosyltransferase (NDT) enzymes, polypeptides having NDT activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing NDT enzymes are also provided. The present invention further provides compositions comprising the NDT enzymes and methods of using the engineered NDT enzymes. The present invention finds particular use in the production of pharmaceutical compounds.Type: ApplicationFiled: August 10, 2022Publication date: May 1, 2025Inventors: Margie Tabuga Borra-Garske, Oscar Alvizo, Lillian Jasmine Miller, Aksiniya Lyubenova Petkova, Mark Huffman, Agustina Rodriguez-Granillo
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Publication number: 20240060064Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.Type: ApplicationFiled: September 14, 2023Publication date: February 22, 2024Inventors: Scott J. Novick, Xiang Yi, Nikki Dellas, Oscar Alvizo, Jovana Nazor, Da Duan, Vesna Mitchell, Jonathan Vroom, Santhosh Sivaramakrishnan, Nandhitha Subramanian, Jeffrey C. Moore, Mark Huffman, Agustina Rodriguez-Granillo, Deeptak Verma, Grant S. Murphy, Nicholas Marshall, Jay Russell, Keith A. Canada
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Patent number: 11795445Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.Type: GrantFiled: May 10, 2021Date of Patent: October 24, 2023Assignee: Codexis, Inc.Inventors: Scott J. Novick, Xiang Yi, Nikki Dellas, Oscar Alvizo, Jovana Nazor, Da Duan, Vesna Mitchell, Jonathan Vroom, Santhosh Sivaramakrishnan, Nandhitha Subramanian, Jeffrey C. Moore, Mark Huffman, Agustina Rodriguez-Granillo, Deeptak Verma, Grant S. Murphy, Nicholas Marshall, Jay Russell, Keith A. Canada
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Publication number: 20220201422Abstract: A method, apparatus and computer program product are provided controlling transmission of sensor data. First sensor is processed to identify an area of interest and generate a trigger signal to direct the transmission of additional sensor data pertaining to the area of interest. Transmission of sensor data may be identified and/or prioritized based on various factors such as proximity, angle, orientation, interest level, category, rating, sensor type, sensor data quality and/or the like. Certain transmission characteristics may be controlled, directed and/or varied such as quantity, quality, rate of transmission, transmission frequencies and intervals, and/or the like. As such, user experience may be improved, and the consumption and timing of certain computation resources may be improved.Type: ApplicationFiled: December 22, 2020Publication date: June 23, 2022Applicant: HERE GLOBAL B.V.Inventors: Justin Eylander, Landis Mark Huffman, Yao Li, Brian Bilicki, Joshua Finken, Amey Aroskar
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Patent number: 11162105Abstract: The present invention provides engineered purine nucleoside phosphorylase (PNP) enzymes, polypeptides having PNP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PNP enzymes are also provided. The present invention further provides compositions comprising the PNP enzymes and methods of using the engineered PNP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.Type: GrantFiled: July 2, 2019Date of Patent: November 2, 2021Assignee: Codexis, Inc.Inventors: Scott J. Novick, Nikki Dellas, Vesna Mitchell, Da Duan, Jovana Nazor, Oscar Alvizo, Auric Anthony Sowell-Kantz, Jeffrey C. Moore, Mark Huffman, Agustina Rodriguez-Granillo, Deeptak Verma, Nicholas M. Marshall, Jay Russell, Keith A. Canada
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Publication number: 20210261940Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.Type: ApplicationFiled: May 10, 2021Publication date: August 26, 2021Inventors: Scott J. Novick, Xiang Yi, Nikki Dellas, Oscar Alvizo, Jovana Nazor, Da Duan, Vesna Mitchell, Jonathan Vroom, Santhosh Sivaramakrishnan, Nandhitha Subramanian, Jeffrey C. Moore, Mark Huffman, Agustina Rodriguez-Granillo, Deeptak Verma, Grant S. Murphy, Nicholas Marshall, Jay Russell, Keith A. Canada
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Patent number: 11034948Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.Type: GrantFiled: July 2, 2019Date of Patent: June 15, 2021Assignee: Codexis, Inc.Inventors: Scott J. Novick, Xiang Yi, Nikki Dellas, Oscar Alvizo, Jovana Nazor, Da Duan, Vesna Mitchell, Jonathan Vroom, Santhosh Sivaramakrishnan, Nandhitha Subramanian, Jeffrey C. Moore, Mark Huffman, Agustina Rodriguez-Granillo, Deeptak Verma, Grant Murphy, Nicholas M. Marshall, Jay Russell, Keith A. Canada
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Publication number: 20200010823Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.Type: ApplicationFiled: July 2, 2019Publication date: January 9, 2020Inventors: Scott J. Novick, Xiang Yi, Nikki Dellas, Oscar Alvizo, Jovana Nazor, Da Duan, Vesna Mitchell, Jonathan Vroom, Santhosh Sivaramakrishnan, Nandhitha Subramanian, Jeffrey C. Moore, Mark Huffman, Agustina Rodriguez-Granillo, Deeptak Verma, Grant Murphy, Nicholas M. Marshall, Jay Russell, Keith A. Canada
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Publication number: 20200010868Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.Type: ApplicationFiled: July 2, 2019Publication date: January 9, 2020Inventors: Da Duan, Oscar Alvizo, Jovana Nazor, Harvinder Chagger Maniar, James Nicholas Riggins, Jonathan Vroom, Santhosh Sivaramakrishnan, Hao Yang, Anna Fryszkowska, Mark Huffman, Joshua Kolev, Iman Farasat, Agustina Rodriguez-Granillo, Deeptak Verma
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Publication number: 20200010834Abstract: The present invention provides engineered purine nucleoside phosphorylase (PNP) enzymes, polypeptides having PNP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PNP enzymes are also provided. The present invention further provides compositions comprising the PNP enzymes and methods of using the engineered PNP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.Type: ApplicationFiled: July 2, 2019Publication date: January 9, 2020Inventors: Scott J. Novick, Nikki Dellas, Vesna Mitchell, Da Duan, Jovana Nazor, Oscar Alvizo, Auric Anthony Sowell-Kantz, Jeffrey C. Moore, Mark Huffman, Agustina Rodriguez-Granillo, Deeptak Verma, Nicholas M. Marshall, Jay Russell, Keith A. Canada
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Patent number: 10250748Abstract: Systems and methods for unified calling are disclosed. According to one embodiment, the method may include (1) using a soft phone application executed by a computer processor, communicating, to a telephony server, an agent status indicating a readiness of the agent to manually make a telephone call; (2) receiving, on a computer terminal, an indication of a telephone number to call; and (3) manually dialing the telephone number using a telephone. The soft phone application emulates an analog connection with the telephony server.Type: GrantFiled: July 30, 2015Date of Patent: April 2, 2019Assignee: JPMorgan Chase Bank, N.A.Inventors: Mark Huffman, Robert O'Reilly
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Patent number: 9967512Abstract: A portable entertainment system may include a housing, a television and at least one table. The table may be adjustable between a first condition where it forms a portion of the housing and a second condition where table legs are used to support a tabletop onto a ground surface. The television may include a monitor that is adjustable between a first position within the housing interior and a second position outside the housing interior where it is operable for television viewing.Type: GrantFiled: August 28, 2015Date of Patent: May 8, 2018Inventors: Scott Huffman, Mark Huffman
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Publication number: 20160138883Abstract: A bore cleaner for a tank that literally crawls through the bore of the tank, and in the process of crawling through the bore, cleans the interior walls of the bore with very little user intervention or monitoring. The bore cleaner extends and retracts as it moves through the bore of the tank, and as it extends and retracts, brushes on the present invention rub against the inside of the bore of the tank and remove debris. When the bore cleaner reaches one end of the bore of the tank, slight user intervention is necessary to reverse the direction of the brushes on the bore cleaner.Type: ApplicationFiled: November 13, 2015Publication date: May 19, 2016Inventors: Scott Huffman, Mark Huffman
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Publication number: 20160065883Abstract: A portable entertainment system may include a housing, a television and at least one table. The table may be adjustable between a first condition where it forms a portion of the housing and a second condition where table legs are used to support a tabletop onto a ground surface. The television may include a monitor that is adjustable between a first position within the housing interior and a second position outside the housing interior where it is operable for television viewing.Type: ApplicationFiled: August 28, 2015Publication date: March 3, 2016Inventors: Scott Huffman, Mark Huffman
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Patent number: 9124700Abstract: Systems and methods for unified calling are disclosed. According to one embodiment, the method may include (1) using a soft phone application executed by a computer processor, communicating, to a telephony server, an agent status indicating a readiness of the agent to manually make a telephone call; (2) receiving, on a computer terminal, an indication of a telephone number to call; and (3) manually dialing the telephone number using a telephone. The soft phone application emulates an analog connection with the telephony server.Type: GrantFiled: April 13, 2012Date of Patent: September 1, 2015Assignee: JPMORGAN CHASE BANK, N.A.Inventors: Mark Huffman, Robert O'Reilly
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Patent number: 8545256Abstract: To attach a cable to a NATO slave receptacle, a wire from the cable may be passed through an opening in a cable receiving member and connected to a tab formed on a NATO plug. The cable receiving member may then be attached to the NATO plug. The NATO plug may then be engaged to a NATO slave receptacle to create an electrical connection between the NATO slave receptacle and the cable. If desired, the NATO plug and receiving member can be easily detached from the cable and used with another cable.Type: GrantFiled: December 28, 2010Date of Patent: October 1, 2013Assignee: Graywacke Engineering, Inc.Inventors: Scott Huffman, Mark Huffman
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Publication number: 20120164891Abstract: To attach a cable to a NATO slave receptacle, a wire from the cable may be passed through an opening in a cable receiving member and connected to a tab formed on a NATO plug. The cable receiving member may then be attached to the NATO plug. The NATO plug may then be engaged to a NATO slave receptacle to create an electrical connection between the NATO slave receptacle and the cable. If desired, the NATO plug and receiving member can be easily detached from the cable and used with another cable.Type: ApplicationFiled: December 28, 2010Publication date: June 28, 2012Inventors: Scott Huffman, Mark Huffman
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Patent number: 7847095Abstract: The present invention is concerned with a novel process for the preparation of the compound 5-[[2(R)-[1(R)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4 -tria-zol-3-one. This compound is useful as a substance P (neurokinin-1) receptor antagonist. In particular, the compound is useful e.g., in the treatment of psychiatric disorders, inflammatory diseases and emesis.Type: GrantFiled: April 17, 2003Date of Patent: December 7, 2010Assignee: Merck Sharp & Dohme Corp.Inventors: David Hands, Mark Huffman, Mahmoud S. Kaba, Joseph F. Payack
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Publication number: 20090277474Abstract: A bore cleaner for a tank that literally crawls through the bore of the tank, and in the process of crawling through the bore, cleans the interior walls of the bore with very little user intervention or monitoring. The bore cleaner extends and retracts as it moves through the bore of the tank, and as it extends and retracts, brushes on the present invention rub against the inside of the bore of the tank and remove debris. When the bore cleaner reaches one end of the bore of the tank, slight user intervention is necessary to reverse the direction of the brushes on the bore cleaner.Type: ApplicationFiled: July 17, 2006Publication date: November 12, 2009Inventors: Doug Minnear, Scott Boyd Huffman, Mark Huffman
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Patent number: 7364469Abstract: A NATO slave connector may include a 2-conductor cable designed to permit a maximum current draw of about 35 amperes. The connector may also include: a connection end adapted to connect to a military vehicle's 24 volt battery NATO slave receptacle; a cable end adapted to be electrically wired to a device; and, a protective covering on the outer surface of the connector.Type: GrantFiled: September 29, 2006Date of Patent: April 29, 2008Assignee: Graywacke Engineering, Inc.Inventors: Scott Huffman, Mark Huffman