Patents by Inventor Mark I. Talan

Mark I. Talan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human soluble receptor for advanced glycation end products (sRAGE), methods of preparing human sRAGE, and treatment methods using sRAGE
    Patent number: 9175062
    Abstract: The present disclosure provides a method for recombinant production of human sRAGE in mammalian cells, as well as a human sRAGE having a mammalian post-translational modification and compositions thereof. The present disclosure also provides a method of treating a vascular disease, injury, or inflammation in a mammal by administering to a mammal with a vascular disease, injury, or inflammation a composition comprising human sRAGE having a mammalian post-translational modification, thereby treating the vascular disease, injury, or inflammation in the mammal.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: November 3, 2015
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Li Lin, Sungha Park, Wen Wei, Rui-Ping Xiao, Mark I. Talan, Edward G. Lakatta
  • HUMAN SOLUBLE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS (sRAGE), METHODS OF PREPARING HUMAN sRAGE, AND TREATMENT METHODS USING sRAGE
    Publication number: 20150051136
    Abstract: The present disclosure provides a method for recombinant production of human sRAGE in mammalian cells, as well as a human sRAGE having a mammalian post-translational modification and compositions thereof. The present disclosure also provides a method of treating a vascular disease, injury, or inflammation in a mammal by administering to a mammal with a vascular disease, injury, or inflammation a composition comprising human sRAGE having a mammalian post-translational modification, thereby treating the vascular disease, injury, or inflammation in the mammal.
    Type: Application
    Filed: January 3, 2013
    Publication date: February 19, 2015
    Inventors: Li Lin, Sungha Park, Wen Wei, Rui-Ping Xiao, Mark I. Talan, Edward G. Lakatta