Abstract: An ingestible device includes a cylindrical capsule having a central axis defined therethrough, a proximal end portion, and an atraumatically shaped distal end portion. A propulsion unit is disposed at the proximal end portion of the capsule for effecting movement of the capsule within an in vivo environment.

Abstract: An implantable device is disclosed, comprising: a tube having a first internal lumen comprising one or more microparticles surrounded by a first liquid; a liquid reservoir comprising a flexible cover, in fluid connection with a first end of the first internal lumen, for providing a second liquid to the first internal lumen; a gas reservoir in fluid connection with a second end of the first internal lumen; wherein the microparticles comprise a material configured to be detected by an external device. In some embodiments, the first liquid and the second liquid are the same liquid. In some embodiments, wherein the first liquid and the second liquid are unmixable. In some embodiments, each microparticle has a diameter between 0.5 to 0.9 of the first internal lumen's hydraulic diameter and comprises a material allowing detection of a movement of each microparticle separately by an external device.

Abstract: An ingestible device includes a cylindrical capsule having a central axis defined therethrough, a proximal end portion, and an atraumatically shaped distal end portion. A propulsion unit is disposed at the proximal end portion of the capsule for effecting movement of the capsule within an in vivo environment.